A5114223661- Systemic Lupus Erythematosus Research
- Cutaneous lymphoproliferative disorders research
- Ocular Diseases and Behçet’s Syndrome
- Lymphoma Diagnosis and Treatment
- Cell Adhesion Molecules Research
- Retinal and Optic Conditions
- Eosinophilic Disorders and Syndromes
- Extracellular vesicles in disease
- Bartonella species infections research
- Cancer and Skin Lesions
- Vascular Tumors and Angiosarcomas
- Reconstructive Facial Surgery Techniques
- Biomedical Ethics and Regulation
- Bioactive Compounds and Antitumor Agents
- Vasculitis and related conditions
- Diabetes and associated disorders
- ATP Synthase and ATPases Research
- Nail Diseases and Treatments
- Skin Diseases and Diabetes
- Cutaneous Melanoma Detection and Management
- Reconstructive Surgery and Microvascular Techniques
- Nonmelanoma Skin Cancer Studies
- Autoimmune Bullous Skin Diseases
- Mast cells and histamine
- Nanoparticle-Based Drug Delivery
Memorial Sloan Kettering Cancer Center
2024
Memorial Ankara Hospital
2024
Helios Klinikum Krefeld
2013-2019
Innsbruck Medical University
2006-2013
Universität Innsbruck
2003
Abstract Objective Behçet's disease ( BD ) is a chronic, relapsing, inflammatory vascular with no pathognomonic test. Low sensitivity of the currently applied International Study Group ISG clinical diagnostic criteria led to their reassessment. Methods An Team for Revision Criteria (from 27 countries) submitted data from 2556 clinically diagnosed patients and 1163 controls ‐mimicking diseases or presenting at least one major sign. These were randomly divided into training validation sets....
Pleomorphic dermal sarcomas (PDS) are frequent UV-induced of the skin intermediate grade malignant potential. Despite fact that PDS have a noteworthy potential to recur (up 28%) as well metastasize 20%), there no specific clinical guidelines with respect follow-up these patients. Moreover, little is known about clinical, histological or molecular prognostic factors in PDS.The aim present study was identify risk predict relapse large multicentre sample cohort which could aid optimize...
Metallothioneins (MT) are ubiquitous, intracellular small proteins with high affinity for heavy metal ions. In the last decades, it was shown that MT overexpression in a variety of cancers is associated resistance to anticancer drugs and combined poor prognosis. this prospective study, we examined role melanoma patients as prognostic factor progression survival. Between 1993 2004, 3386 primary cutaneous were investigated by using monoclonal antibody against on routinely fixed,...
Aims: Necrobiosis lipoidica (NL) is a chronic inflammatory skin disease with unknown aetiology. The aim was to determine the presence of spirochaetal microorganisms in NL. Methods and results: Focus‐floating microscopy (FFM) modified immunohistochemical technique that developed detect borrelial spirochaetes within tissue sections. It has proven be more sensitive for detection than polymerase chain reaction (PCR). Fifty‐six cases NL as well 44 negative 33 positive controls were investigated...
Hepatitis C virus (HCV) infection causes not only acute and chronic liver disease, but also extrahepatic symptoms. To our knowledge, this is the first case report of a patient who developed simultaneously subacute cutaneous lupus erythematosus small CD20+ B-cell clone because HCV relapse after standard care therapy (pegylated interferon plus ribavirin). Treatment with rituximab, chimeric anti-CD20 monoclonal antibody, was successful.
Currently there are no laboratory markers that correlate well with the clinical findings in BD. Therefore assessment of disease activity has to be based on history features. There have been several attempts develop measurements: (1) scheme use by H Yazici (1984; evaluation depends features found day patient attends clinic); (2) Iranian Behcet's Dynamic Measure (IBDDAM; F Davatchi 1991; accurate symptoms up 12 months prior date assessment); and (3) European (1991; initially developed UK...
Background/Aims: Tumor response to radiation is thought depend on the direct killing of tumor cells. Our laboratory has called this into question. Firstly, we showed that biology host, specifically endothelial expression acid sphingomyelinase (ASMase), was critical in determining radiocurability. Secondly, have shown immune system can enhance by allowing a complete control hemi-irradiated tumors. In paper, focus integration these two findings. Methods: We used Lewis Lung Carcinoma (LLC)...
An 80-year-old man presented with a 2-month history of asymptomatic livid brown nodules on his right thigh, where two previous hip operations were done for replacement. Histopathological examination revealed an intensive hyperplasia lymphatic vessels mixed dermal infiltrate composed mainly lymphocytes, histiocytes and plasma cells. We describe rare case intralymphatic histiocytosis, which is benign process chronic course.
Primär kutane B-Zell-Lymphome (primary cutaneous B-cell lymphomas: PCBCL) stellen extranodale Non-Hodgkin-Lymphome reifer B-Lymphozyten dar, die Haut als Zielorgan haben und dort proliferieren. Sie zeigen eine große Bandbreite klinischer histologischer Erscheinungsformen. Ca. 22 % der kutanen Lymphome (cutaneous CL) entfallen auf CBCL), 73 T-Zell-Lymphome T-cell CTCL) < 10 werden seltenen Formen von CL zugeordnet. Die Inzidenz ist weiterhin zunehmend wird basierend den Daten aus USA...
We describe a case of neutrophil rich variant primary cutaneous anaplastic large cell lymphoma (PCALCL) and the clinicopathological features cases reported in literature. In all male to female ratio is 1.4 : 1. The age at presentation ranges between 12 82 years with mean 50.73 years. Various clinical lesions including nodules (47.8 %), tumormasses (34.8 plaques (21.7 %) unusual variants (13.4 are noted. 47.8 % associated ulceration. Multifocal seen about 18.4 cases. Lesions located...
Es stellte sich uns ein 63-jähriger Patient mit seit Wochen bestehenden juckenden Hautveränderungen vor. Da er des Weiteren Dysphagien sowie Erosionen im Rachenbereich zu beklagen hatte, wurde hausärztlich eine antibiotische Therapie eingeleitet, die jedoch keiner Befundbesserung führte. Wir entnahmen stationär einige Probebiopsien und konnten in den Präparaten zahlreiche Plasmazellen entdecken. Zur Sicherheit Labordiagnostik um Lues- Borrelienserologie erweitert. Hierbei ließ floride...
Die histologische Untersuchung von Hautveränderungen spielt eine Schlüsselrolle in der Diagnostik des kutanen Lupus erythematodes (LE). LE zeigt ein breites Spektrum histopathologischer Kriterien, das vom Stadium Läsionen abhängt. hauptsächlichen Subtypen werden beschrieben und die bedeutendsten Differenzialdiagnosen diskutiert.