A5067952267- Pulmonary Hypertension Research and Treatments
- Advanced Radiotherapy Techniques
- Advances in Oncology and Radiotherapy
- Vascular Anomalies and Treatments
- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Venous Thromboembolism Diagnosis and Management
- Radiomics and Machine Learning in Medical Imaging
- Cervical Cancer and HPV Research
- Radiation Dose and Imaging
- Cardiovascular Issues in Pregnancy
- Endometrial and Cervical Cancer Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Soft tissue tumor case studies
- Blood Coagulation and Thrombosis Mechanisms
- Ovarian cancer diagnosis and treatment
- Head and Neck Cancer Studies
- Cardiovascular Function and Risk Factors
- Ocular Diseases and Behçet’s Syndrome
- Retinal and Optic Conditions
- Amoebic Infections and Treatments
- Lung Cancer Treatments and Mutations
- Sarcoma Diagnosis and Treatment
- Nonmelanoma Skin Cancer Studies
- Lung Cancer Diagnosis and Treatment
Pontifícia Universidade Católica de Minas Gerais
2025
Hospital de Santo António
2008-2024
Instituto Português de Oncologia Francisco Gentil
1995-2024
IPO Porto
1995-2023
Centro Hospitalar do Porto
2009-2022
Radiation Oncology Associates
2020
Universidad Fernando Pessoa Canarias
2020
Universidade Nova de Lisboa
2019
Rede de Química e Tecnologia
2019
Universidade Estadual de Campinas (UNICAMP)
2018-2019
Abstract Objective Behçet's disease ( BD ) is a chronic, relapsing, inflammatory vascular with no pathognomonic test. Low sensitivity of the currently applied International Study Group ISG clinical diagnostic criteria led to their reassessment. Methods An Team for Revision Criteria (from 27 countries) submitted data from 2556 clinically diagnosed patients and 1163 controls ‐mimicking diseases or presenting at least one major sign. These were randomly divided into training validation sets....
INTRODUÇÃO: A hemorragia pós parto (HPP) é definida como a perda sanguínea anormal, sendo acima de 500 ml em normal e 1.000 cesário, ou uma capaz gerar instabilidade hemodinâmica. OBJETIVO: O objetivo do presente trabalho analisar comparar o perfil epidemiológico qualitativo das internações causadas por HPP no período 10 anos na população fértil Brasília São Paulo. METODOLOGIA: estudo trata-se um ecológico, descritivo, transversal retrospectivo. Os dados foram coletados respeito dos casos...
A comprehensive literature review was conducted to summarise existing evidence and the latest therapeutic advancements in feline HCM. The disease phenotype is characterised by development of concentric hypertrophy, which variable but often asymmetric, primarily affecting left ventricle. HCM marked diastolic dysfunction, resulting a reduced intracavitary internal diameter due disordered alignment cardiomyocytes excessive collagen deposition, thickens myocardial tissue impairs relaxation....
Health-related quality of life (HRQoL) impairment is common in pulmonary hypertension (PH), but its clinical predictors are not well established. This study aims to characterize the HRQoL patients with arterial (PAH) and other precapillary forms PH (pcPH) explore correlates.
Abstract Venous thromboembolism (VTE) is a leading cause of death among cancer patients. Khorana score (KS) the most studied tool to predict cancer-related VTE, however, it exerts poor sensitivity. Several single-nucleotide polymorphisms (SNPs) have been associated with VTE risk in general population, but whether they are predictors matter discussion. Compared other solid tumours, little known about setting cervical (CC) and thrombogenesis-related could be valuable biomarkers patients this...
The impact of Behçet's disease on higher cognitive functions is still poorly understood. We proposed (1) to characterize the neuropsychological profile patients with (Neuro‐BD) and without (BD) neurological manifestations; (2) identify which clinical, psychopathological, genetic variables are related performance; (3) explore association between functioning neuroimaging findings in BD patients. Fifteen Neuro‐BD 35 nonactive phase their illness underwent a examination, performed comprehensive...
Unlike acute pulmonary embolism (PE), the resolution of thrombi is ineffective in chronic thromboembolic hypertension (CTEPH), leading to reorganisation and fibrotic changes within arteries. The authors report case a man his 60s with polycythemia vera, under warfarin, following an PE. He was admitted year later right heart failure haemodynamic instability. Acute over PE caused this severe presentation, confirmed by catheterisation scintigraphy. challenging diagnosis management involved...
This study aims to assess the long-term survival of pulmonary arterial hypertension (PAH) and chronic thromboembolic (CTEPH) patients followed in a Portuguese (PH) referral center. We studied PAH CTEPH diagnosed between January 2005 December 2016. Cumulative was estimated using Kaplan-Meier method. Survival trends were compared over two periods (2005-2010 vs. 2011-2016). Of 142 PH (age 54±18 years; 31% male), 47 had 95 group 1 PH. Most with idiopathic/heritable (I/HPAH) NYHA III-IV at...
Patients with pulmonary arterial hypertension (PAH) and other forms of precapillary (PH) have impaired quality life (QoL). The Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR) is a PH-specific patient-reported outcome measure that assesses symptoms, activity limitations QoL. It was originally developed in UK-English. main objective this study to create an adaptation the CAMPHOR suitable for Portuguese-speaking population. A multi-step approach followed: bilingual lay panel...
Pulmonary hypertension (PH) is a heterogeneous, debilitating condition with highly relevant impact on functional capacity, quality of life, and life-expectancy. This study aims to provide long-term data the Portuguese PH population, by characterising clinical presentation, evolution, outcomes patients in specialised referral centre. Retrospective analysis cohort 101 pre-capillary (pcPH) referenced an expert tertiary care centre northern Portugal from 2002 2013. Diagnosis was confirmed right...
To evaluate the effects of complete denture (CD) quality and user satisfaction on use CDs provided by primary care services at 1 5 years postinsertion.A random sample 233 individuals were evaluated regarding maxillary and/or mandibular after insertion; both time points, quality, integrity, measured. The covariates included age, gender, marital status, education, family income, past CD, since teeth loss, ridge height, frequency return visits to dentist receiving prostheses. effect variables...
Although previously reported, the existence of a neurofibromatosis (NF)-associated diffuse lung disease (DLD) still lacks solid evidence. We report case 68-year-old non-smoking female with NF1, pre-capillary pulmonary hypertension (PH) and an interstitial pattern. Initial findings included progressive dyspnea, hypoxemia sparse centrilobular ground-glass micronodules on high-resolution computed tomography (HRCT). Further study demonstrated severe defect in diffusing capacity for carbon...
Abstract Purpose To perform a clinical audit to assess adherence standard practice for the diagnosis, treatment, and follow-up of patients undergoing radiotherapy rectal cancer treatment in four European countries. Materials methods Multi-institutional, retrospective cohort study 221 treated 2015 at six centres. Clinical indicators applicable general processes were evaluated. All data obtained from electronic medical records. Results The audits performed year 2017. We found substantial...
Introducao: Os abcessos hepaticos constituem uma entidade clinica que coloca desafios no diagnostico e tratamento, sendo em muito casos necessario um elevado indice de suspeicao. A maioria dos piogenicos sao polimicrobianos. agentes entericos facultativos anaerobios os mais comuns. Na literatura revista, a Staphylococcus aureus cerca 7% piogenicos. Esta infeccao habitualmente resulta disseminacao hematogenea microrganismos isolados infeccoes distância. Nao existem series publicadas sobre...
Intravenous (i.v.) prostacyclin is the cornerstone treatment in high-risk pulmonary arterial hypertension (PAH) patients. Selexipag an orally available receptor agonist. Limited data are regarding feasibility of transitioning from i.v. epoprostenol to selexipag. A 50-year-old woman with idiopathic PAH was diagnosed a World Health Organization (WHO) Functional Class (FC) IV. She improved upfront triple combination therapy, including epoprostenol. Over 2 years follow-up, patient remained at...
To assess adherence to standard clinical practice for the diagnosis and treatment of patients undergoing prostate cancer (PCa) radiotherapy in four European countries using audits as part international IROCA project. Multi-institutional, retrospective cohort study 240 randomly-selected treated PCa (n = 40/centre) year 2015 at six hospitals. Clinical indicators applicable general PCa-specific processes were evaluated. All data obtained directly from medical records. The performed 2017....
Limited data are available on physical activity (PhA) levels in chronic thromboembolic pulmonary hypertension (CTEPH) patients, as well the clinical utility of PhA measurements using questionnaires and accelerometers. We aimed to study CTEPH patients their correlates, compare measured by International Physical Activity Questionnaire (IPAQ) with measures from This is a cross-sectional (n = 50). were accelerometers (IPAQ). Clinical parameters evaluated walked distance 6-min-walking test...