A5073074653- Genetic factors in colorectal cancer
- Colorectal Cancer Screening and Detection
- Bone Metabolism and Diseases
- TGF-β signaling in diseases
- Gastric Cancer Management and Outcomes
- Sarcoma Diagnosis and Treatment
- Spinal Fractures and Fixation Techniques
- Medical Imaging and Analysis
- Multiple and Secondary Primary Cancers
- Healthcare cost, quality, practices
- Colorectal Cancer Surgical Treatments
- Spine and Intervertebral Disc Pathology
- Reproductive Health and Contraception
- Endometrial and Cervical Cancer Treatments
- Cancer Cells and Metastasis
- Vascular Tumors and Angiosarcomas
- Radiopharmaceutical Chemistry and Applications
- Metastasis and carcinoma case studies
- Clinical practice guidelines implementation
- Anatomy and Medical Technology
- Bone Tumor Diagnosis and Treatments
- Cancer Research and Treatments
- Caveolin-1 and cellular processes
- Lung Cancer Treatments and Mutations
- Bone health and treatments
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Energy Storage Systems (United States)
2022
Wind Power Engineering (Japan)
2022
Zhejiang Chinese Medical University
2021
Second Affiliated Hospital of Zhejiang University
2021
Bioscience (China)
2019-2020
Sixth Affiliated Hospital of Sun Yat-sen University
2017
Sun Yat-sen University
2017
First Hospital of Jilin University
2017
Jilin University
2017
Abstract Background: Although the incidence of colorectal cancer is steadily increasing, screening for with conventional approaches not routinely performed in China. Noninvasive methods are attractive options to resolve this issue. Syndecan-2 (SDC2) frequently methylated cancer. However, value a stool test SDC2 detection unknown. Methods: Methylation status was tested cell lines and 398 tissue samples further evaluated 497 samples, including 196 from patients, 122 adenoma 179 normal...
Abstract Background and Aims Stool DNA testing is an emerging attractive option for colorectal cancer (CRC) screening. We previously evaluated the feasibility of a stool (sDNA) test methylated SDC2 CRC detection. The aim this study was to assess its performance in multicenter clinical trial setting. Methods Each participant required undergo sDNA reference colonoscopy. consists quantitative assessment methylation status promoter. Results real-time methylation-specific PCR were dichotomized as...
Abstract Background BMP3 gene is often found hypermethylated and hence inactivated in several types of cancers including colorectal cancer (CRC), indicating that it has a suppressor role carcinogenesis. Though reliable biomarker for screening CRC, the molecular mechanism carcinogenesis remains largely unknown. Methods The expression level was examined by immunohistochemistry staining western blot. Methylation-specific PCR (MSP) real-time quantitative MSP were used to test hypermethylation...
Objective: To investigate the clinicopathological characteristics, MSI and K-ras mutation of double primary malignancies (DPM) associated with colorectal cancer (CRC). Methods: From January 2015 to December 2016, data CRC patients treated by surgery in Affiliated Drum Tower Hospital Nanjing University Medical School were collected, clinical was analyzed. Multiplex real-time fluorescence quantitative PCR amplification refractory performed identify gene mutations. Results: Of all CRC, 5.2%...
Bone metastasis from endometrial cancer (EC) is rare and poorly described. The purpose of the present study was to investigate correlation between clinically accessible factors survival time among EC patients with bone metastasis.We retrospectively identified reviewed 2010 2016, based on Surveillance, Epidemiology End Results (SEER) database. Univariable multivariable Cox regressions were applied evaluate effects clinical variables survival. Kaplan-Meier plots used visually demonstrate...
To investigate the distribution of CD44(+)/CD24(-) cells in breast cancers relation to tumor size before and after administration neoadjuvant chemotherapy.CD44(+)/CD24(-) obtained from cancer specimens were characterized vivo vitro using formation assays mammosphere generation assays, respectively. The CD44+/CD24- 78 following chemotherapy was also evaluated immunofluorescence this compared with extent invasion predicted by Response Evaluation Criteria Solid Tumours (RECIST).In 27/78 cases,...
Objective To design the disease transfer table of standardized communication between maternity ward and operating room, explore application effect based on situation (S)-background (B) -assessment (A) -recommendation (R) in cesarean delivery maternal. Methods 570 pregnant women 30 medical staff from two wards were selected as research object, first was control group, second observation group. The group used traditional way transfer, SBAR transition for compared incidence adverse...
1571 Background: While older studies suggest that certain contraceptive medications can increase the risk of breast and cervical cancers protect against ovarian endometrial cancer, little is known about cancer risks associated with new generation combined hormone contraception (CHCs) drugs. The CHCs utilize same types hormones (estrogen progestin), but contain lower levels estrogen at 15-35 mcg/day compared to 150 in CHCs. objective this study was examine association specific (OrthoEvra,...
Abstract Study purpose: Previously, we had a pilot study to evaluate the feasibility of stool DNA test methylated Syndycan-2 (SDC2) for colorectal cancer (CRC) detection. The purpose this continuing investigation was assess performance in multicenter hospital-based setting. Methods: Each participant required undergo both and reference colonoscopy. assesses methylation status single target SDC2 gene. Results real-time methylation-specific PCR were dichotomized as positive negative by...
Research on wall transition control of double-body negative pressure wall-climbing
Purpose: Given the poor prognosis and relative rarity of patients diagnosed with limb rhabdomyosarcoma (LRMS) metastasis at diagnosis, we performed this study to reveal distinctive clinical features evaluated prognostic factors special population in order provide appropriate treatment. Patients Methods: We carried out retrospective research LRMS from 1975 2016 using Surveillance, Epidemiology, End Results (SEER) program database. Survival curves were generated by applying Kaplan-Meier...