A5024966393- Facial Trauma and Fracture Management
- Reconstructive Facial Surgery Techniques
- Periodontal Regeneration and Treatments
- Dental Radiography and Imaging
- Dental Implant Techniques and Outcomes
- Organ and Tissue Transplantation Research
- Reconstructive Surgery and Microvascular Techniques
- Oral and Maxillofacial Pathology
- Facial Nerve Paralysis Treatment and Research
- Pain Management and Treatment
- Sarcoma Diagnosis and Treatment
- Craniofacial Disorders and Treatments
- Cancer Diagnosis and Treatment
- Mesenchymal stem cell research
- Cancer Cells and Metastasis
- Digital Imaging in Medicine
- Bone Tissue Engineering Materials
- Cancer Genomics and Diagnostics
- Spinal Fractures and Fixation Techniques
- Bone Tumor Diagnosis and Treatments
- Research in Social Sciences
- Ocular Disorders and Treatments
- Zebrafish Biomedical Research Applications
- Manufacturing Process and Optimization
- Vascular Tumors and Angiosarcomas
University of Helsinki
2013-2024
Helsinki University Hospital
2014-2024
Purpose The purpose of this paper is to develop a workflow for 3D modeling and additive manufacturing (AM) patient‐specific medical implants. comprehensive consists four steps: imaging; modelling; manufacturing; clinical application. Implants are used reconstruct bone damage or defects caused by trauma disease. Traditionally, implants have been manually bent shaped, either preoperatively intraoperatively, with the help anatomic solid models. proposed obviates manual procedure may result in...
Currently, in vivo model for personalised cancer drug testing is challenging. A zebrafish larvae xenograft has been applied recent years to research, particularly purposes, showing promising results against patient-derived tumour xenografts. these models apply imaging techniques measure efficacy. However, this method carries several limitations, including timely imaging, thereby reducing the available number of tested fish and drugs. Here, we propose a PCR-based fast assay evaluate efficacy...
Study Design: Retrospective cohort study. Objective: In orthopedic surgery, the use of antibiotic-impregnated spacers is a well-established method for treating periprosthetic joint infections with excellent outcomes. However, their application in head and neck surgery remains poorly documented, despite high susceptibility these patients to persistent infections. The objective this study was evaluate 10-year outcomes antibiotic treatment mandibular unresponsive conventional methods, prior...
The use of rapid prototyping (RP) models in medicine to construct bony is increasing.The aim the study was evaluate retrospectively indication for RP oral and maxillofacial surgery at Helsinki University Central Hospital during 2009-2010. Also, used computed tomography (CT) examination - multislice CT (MSCT) or cone beam (CBCT) method evaluated.In total 114 were fabricated 102 patients. mean age patients time production model 50.4 years. indications modelling included malignant lesions...
Renal cell carcinomas (RCCs) have a tendency to metastasize at an early stage, therefore, the patients frequently exhibit metastatic disease time of diagnosis. Common locations for metastases are adjacent organs and abdominal lymph nodes; however, occasionally metastasis peripheral may be initial clinical symptom. The 71‑year‑old male patient in current case suffered from radioresistant aggressively behaving RCC mandible lower lip, which was successfully managed by surgical resection. facial...
A major challenge with extensive craniomaxillofacial bone reconstruction is the limited donor-site availability to reconstruct defects predictably and accurately according anatomical shape of patient. Here, patient-specific composite bioimplants, consisting cross-linked poly(trimethylene carbonate) (PTMC) networks β-tricalcium phosphate (β-TCP), are tested in vivo twelve Göttingen minipigs a large mandibular continuity defect model. The 25 mm supported by titanium plates receive either...
Abstract Objectives The primary aim of the present study was to compare head and neck cancer treatment modality surgery with radiotherapy or chemoradiotherapy alone for dental implant (DI) survival. second evaluate prevalence mucosal overgrowth around DI after without grafts. Materials methods An observational retrospective consisted 59 patients malignant tumors that received between 2015 2019. Treatment modalities together information on oral rehabilitation DI, overgrowth, precursor lesions...
•Patient selection is crucial in avoiding post face transplantation complications•To avoid complications, donors' oral health should be examined•We were able to successfully place dental implants transplanted jaws•To ensure function of parotid glands, papilla position must noted during surgery•Preventive measures are key due dry mouth and the related risk for diseases ObjectivesOral balanced occlusion important aspects a well-functioning transplant. This study describes status, management,...
Carotid interposition graft (CIG) surgery in the setting of head & neck cancer (HNC) is a rare procedure with limited number cases described literature.To assess outcomes at Helsinki University Hospital.Patients who underwent CIG and tumor were retrospectively analyzed over 15 years. Overall-survival (OS) was calculated until 1 May 2020. The primary-outcome to measure 30-day OS, postoperative stroke rate, other complications. secondary-outcome 1-, 2-, 5-year OS.Thirteen patients identified,...
Tumors of the oral cavity often require extensive resections leading to significant hard and soft tissue defects. Microvascular free flaps, consisting both tissue, are required in reconstructions. Hybrid composed two different joint offer potential alternatives for head neck reconstruction. This report presents our results with a modified hybrid ALT/DCIA, that is, minihybrid flap (MH-flap) anterolateral thigh (ALT) partial inner lamina iliac crest only (partial DCIA) reconstruction...