A5037162204- Pain Mechanisms and Treatments
- Peripheral Neuropathies and Disorders
- Transplantation: Methods and Outcomes
- Glycogen Storage Diseases and Myoclonus
- Adenosine and Purinergic Signaling
- Balance, Gait, and Falls Prevention
- Musculoskeletal pain and rehabilitation
- Phytochemistry and Bioactivity Studies
- Epigenetics and DNA Methylation
- Nephrotoxicity and Medicinal Plants
- Hedgehog Signaling Pathway Studies
- Renal Transplantation Outcomes and Treatments
- Silymarin and Mushroom Poisoning
- Vagus Nerve Stimulation Research
- Glioma Diagnosis and Treatment
- Oral and gingival health research
- Neurological disorders and treatments
- Botulinum Toxin and Related Neurological Disorders
- Effects of Vibration on Health
University Medical Center Groningen
2020-2024
University of Groningen
2020-2024
Ludwig-Maximilians-Universität München
2013
First Pavlov State Medical University of St. Petersburg
2013
Emory University
2013
Cook Children's Medical Center
2013
McMaster University
2011
Background/Objectives: Tacrolimus dosing traditionally relies on therapeutic drug monitoring in whole blood, while assessment plasma may better reflect its effect and reveal overdosing impacting health-related quality of life (HRQoL). Methods: In this cross-sectional study, 898 kidney transplant recipients (KTRs) who were at least 12 months post-transplantation included. Plasma blood tacrolimus concentrations compared using Passing–Bablok regression analyses Bland–Altman plots. Furthermore,...
Solid organ transplant recipients (SOTR) frequently report tremor. Data concerning tremor-related impairment and its potential impact on health-related quality of life (HRQoL) are lacking. This cross-sectional study assesses tremor activities daily living HRQoL using validated questionnaires among SOTR enrolled in the TransplantLines Biobank Cohort Study. We included 689 (38.5% female, mean [±SD] age 58 [±14] years) at median [interquartile range] 3 [1–9] years after transplantation, which...
Abstract Background and purpose Tremor is a frequent complaint of solid organ transplant recipients. We report on the largest population investigated with clinical neurophysiological methods. Our aim to objectively establish tremor prevalence syndrome in Methods was measured heart, kidney, liver, lung recipients, using accelerometers during rest, postural, weight‐loaded conditions. The 95th percentile healthy kidney donors' amplitude used as cutoff determine presence frequency, frequency...
Measuring vibration perception threshold (VPT) accurately classifies and quantifies the severity of loss perception. A biothesiometer (Bio-thesiometer®; Bio Medical Instrument Co, Ohio, USA) appears to be most suitable tool determine VPT due its low inter-rater variability occurence adaption sensation. Different values for a have been described, however, specification on age, height different measurement locations is currently lacking. The objective our study was identify determinants in...
Introduction: Even after successful transplantation, solid organ transplant recipients (SOTR) have reduced health-related quality of life (HRQoL) compared to the general population. A main cause is occurrence side effects immunosuppressive therapy, generally including calcineurin inhibitors (CNI). One these side-effects tremor, which can be very debilitating in daily life. Currently, large studies assessing burden tremor among SOTR are lacking. We therefore aimed investigate prevalence and...