- Advanced Photocatalysis Techniques
- Advanced oxidation water treatment
- Sirtuins and Resveratrol in Medicine
- Microbial Fuel Cells and Bioremediation
- vaccines and immunoinformatics approaches
- RNA modifications and cancer
- Ubiquitin and proteasome pathways
- Single-cell and spatial transcriptomics
- Computational Drug Discovery Methods
- Pancreatic and Hepatic Oncology Research
- Protein Degradation and Inhibitors
- Photoreceptor and optogenetics research
- CAR-T cell therapy research
- Advanced Nanomaterials in Catalysis
- Neuroblastoma Research and Treatments
- Arsenic contamination and mitigation
- SARS-CoV-2 and COVID-19 Research
- Cancer, Lipids, and Metabolism
- Photosynthetic Processes and Mechanisms
Peking University
2014-2024
Jinan University
2024
This review summarizes the key roles of various vacancy defects in PS-AOPs and provides insights into understanding defect persulfate activation to promote development water treatments.
Neuroblastoma is the most common pediatric extracranial solid tumor with a broad spectrum of clinical behavior and poor prognosis. Despite intensive multimodal therapy, ongoing trials, basic science investigations, neuroblastoma remains complex medical challenge long-term survival rate less than 40%. In our study, we found that resveratrol (3, 5, 4′-trihydroxystilbene, RSV), naturally occurring phytoalexin, possesses an anticancer activity through blocking cell growth inducing apoptosis in...
We explore how microfluidic-based high-throughput single-cell RNA sequencing facilitates neutralizing monoclonal antibody development against SARS-CoV-2, and the potential improvement of therapeutic discovery strategies.
The search for pharmaceutical treatment COVID-19 has been progressive. Currently approved medicines include therapeutic antibodies and antiviral drugs. However, the effectiveness of current drugs is far from satisfactory, which suggests necessity improvement. In this research, we selected non-structural protein complex Nsp16-Nsp10, responsible methylating SARS-CoV-2’s RNA, as a drug target. With computer-aided development technology, screened two potential either by inhibiting SAM catalytic...
Colorectal cancer (CRC) is a leading cause of deaths worldwide. Nevertheless, the exact mechanism CRC occurrence remains unclear, and it lack biomarkers for early detection. In this study, we employed TMT-based quantitative proteomic approach to analyze changes in sera collected from early-staged colorectal patient healthy volunteers. Among 282 proteins identified, total 76 were found differentially expressed patients. Bioinformatics analysis revealed that related focal adhesion p53...