A5101901366- Acute Lymphoblastic Leukemia research
- Coronary Interventions and Diagnostics
- Cardiovascular Disease and Adiposity
- Acute Myocardial Infarction Research
- Cardiovascular Effects of Exercise
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Genetically Modified Organisms Research
- Cancer-related molecular mechanisms research
- Lung Cancer Treatments and Mutations
- Cancer, Hypoxia, and Metabolism
- Sulfur-Based Synthesis Techniques
- Atrial Fibrillation Management and Outcomes
- Asymmetric Synthesis and Catalysis
- Acute Myeloid Leukemia Research
- Transgenic Plants and Applications
- Sirtuins and Resveratrol in Medicine
- Radio Frequency Integrated Circuit Design
- Glutathione Transferases and Polymorphisms
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Organic and Inorganic Chemical Reactions
- Synthesis of Indole Derivatives
- MicroRNA in disease regulation
- Ubiquitin and proteasome pathways
- Pharmacovigilance and Adverse Drug Reactions
Xuzhou Medical College
2023-2025
Dali University
2024
Affiliated Hospital of Xuzhou Medical College
2024
Hebei University of Engineering
2024
Xingtai People's Hospital
2020-2021
Hebei Medical University
2020-2021
Hospital of Hebei Province
2020
Tianjin University
2018-2019
Shandong Normal University
2016-2017
Peking University
2003-2014
Neuroblastoma is the most common pediatric extracranial solid tumor with a broad spectrum of clinical behavior and poor prognosis. Despite intensive multimodal therapy, ongoing trials, basic science investigations, neuroblastoma remains complex medical challenge long-term survival rate less than 40%. In our study, we found that resveratrol (3, 5, 4′-trihydroxystilbene, RSV), naturally occurring phytoalexin, possesses an anticancer activity through blocking cell growth inducing apoptosis in...
MicroRNAs (miRNAs) and reactive oxygen species (ROS) are concurrently implicated in heart ischemia-reperfusion (IR) injury. There may exist mutual cross-talk between miRNAs ROS cardiac IR injury process. In this study, we developed a novel crown-like silica@polydopamine-DNA-CeO2 nanocomposite by assembly of silica@polydopamine-DNA1 nanoparticles decorated with satellite CeO2-DNA2 for detecting imaging microRNA-21 (miR-21) hydrogen peroxide (H2O2) simulated living cells vivo. The miRNA-21 was...
Abstract Background Spectral processing and post-experimental data analysis are the major tasks in NMR-based metabonomics studies. While there commercial free licensed software tools available to assist these tasks, researchers usually have use multiple packages for their studies because generally focus on specific tasks. It would be beneficial a highly integrated platform, which can completed within one package. Moreover, with open source architecture, newly proposed algorithms or methods...
Abstract The application of asymmetric phase‐transfer catalysis to the Strecker reaction ketimines was realized utilizing bifunctional thiourea‐phosphonium salts. aldimines also quaternary ammonium salts derived from amino acids. magnified image
1,2,4-Triazolines and 1,2,4-triazoles can be synthesized under visible light in one step without additional operations, which also scaled up to a gram-level.
Background Current research suggests that microvascular obstruction (MVO) following the first percutaneous coronary intervention (PCI) in myocardial infarction patients is closely related to inflammatory responses. The lymphocyte-to-C-reactive protein (CRP) ratio (LCR), as a novel marker, associated with prognosis of ST-segment elevation (STEMI). However, relationship between LCR and MVO remains unclear. This study aims investigate correlation STEMI undergoing PCI. Methods was single-center...
Abstract A remote cross Rauhut−Currier reaction utilizing vinyl ketones and para ‐quinone methides derived from isatins was realized, which successfully catalyzed using bifunctional phosphines, furnishing chiral 3,3‐disubstituted oxindoles in excellent enantioselectivities high yields. The mechanistic studies demonstrated the key role of alkyl hydrogen ketones, conceivably interacted with methide carbonyl group via bond, offering a new insight for design novel asymmetric reactions. magnified image
Chlorocuprate(<sc>i</sc>) ionic liquids can be well-stabilized, low-cost, efficient and green non-mercury catalysts for hydrochlorination of acetylene.
Microvascular obstruction (MVO) develops in approximately 50% of patients with ST-segment elevation myocardial infarction (STEMI) after undergoing percutaneous coronary intervention (PCI). MVO is strongly linked to inflammation, fibrosis, and adverse clinical outcomes. Soluble suppression tumorigenicity 2 (sST2) serves as a biomarker for inflammation fibrosis. Yet, the correlation between sST2 STEMI has not been fully elucidated. This study attempts evaluate association levels following...
Objective: To analyze the pregnancy outcome, influencing factors and recurrence of fertility-preserving therapy for women with atypical endometrial hyperplasia (AEH) or carcinoma (EC). Methods: The multi-center retrospective study included 107 AEH EC in 10 hospitals from January 1st, 2009 to December 31st, 2018. clinical rate, live birth rate 66 patients urgent child-bearing requirements after treatment were analyzed. Results: (1) Among child bearing requirements, 24 chose spontaneous...
The purpose of this study was to evaluate the correlation long non-coding RNA maternally expressed gene 3 (Lnc-MEG3) with disease features, treatment response, and survival in pediatric acute myeloid leukemia (AML) patients.Among 92 de novo AML patients (before after 1 course induction) 40 controls, bone marrow mononuclear cells were obtained. Then, Lnc-MEG3 expression determined by reverse transcription quantitative polymerase chain reaction. After standard induction therapy patients,...
<title>Abstract</title> Background Microvascular obstruction (MVO) develops in approximately 50% of patients with ST-segment elevation myocardial infarction (STEMI) after undergoing percutaneous coronary intervention (PCI). MVO is strongly linked to inflammation, fibrosis, and adverse clinical outcomes. Soluble suppression tumorigenicity 2 (sST2) serves as a biomarker for inflammation fibrosis. Yet, the correlation between sST2 STEMI has not been fully elucidated. This study attempts...