A5080071993- Cardiac Imaging and Diagnostics
- Advanced MRI Techniques and Applications
- Cardiovascular Function and Risk Factors
- Cerebrovascular and Carotid Artery Diseases
- Pulmonary Hypertension Research and Treatments
- Cardiomyopathy and Myosin Studies
- Cardiac Structural Anomalies and Repair
- Coronary Interventions and Diagnostics
- Acute Ischemic Stroke Management
- Cardiovascular Disease and Adiposity
- Sarcoidosis and Beryllium Toxicity Research
- Intracranial Aneurysms: Treatment and Complications
- Cardiac Arrhythmias and Treatments
- Viral Infections and Immunology Research
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Atrial Fibrillation Management and Outcomes
- Advanced X-ray and CT Imaging
- Cardiac electrophysiology and arrhythmias
- Aortic aneurysm repair treatments
- Cardiovascular Effects of Exercise
- Cardiovascular Health and Disease Prevention
- Cardiac pacing and defibrillation studies
- Congenital Heart Disease Studies
- Intracerebral and Subarachnoid Hemorrhage Research
- Pericarditis and Cardiac Tamponade
National Cerebral and Cardiovascular Center
2016-2025
John Wiley & Sons (United States)
2024
Hudson Institute
2024
Tohoku University Hospital
2017-2024
Tohoku University
2007-2022
National Institutes for Quantum Science and Technology
2022
Siemens Healthcare (United States)
2022
Okayama Medical Center
2022
National Hospital Organization
2022
Policlinico S.Orsola-Malpighi
2022
Balloon pulmonary angioplasty (BPA) has been reported to improve haemodynamics and functional capacity, with an acceptable risk, in patients chronic thromboembolic hypertension (CTEPH) who are not candidates for endarterectomy. However, right ventricular (RV) function, important predictor CTEPH, remains be elucidated. We aimed examine the impact of BPA on RV remodelling dysfunction relative haemodynamic improvements inoperable CTEPH. 20 consecutive CTEPH underwent cardiovascular magnetic...
<h3>Background</h3> Gadolinium-enhanced cardiovascular magnetic resonance is an emerging tool for the diagnosis of cardiac sarcoidosis (CS); however, correlations between extent late gadolinium enhancement (LGE) and efficacy steroid therapy adverse outcomes in patients with CS remain unclear. <h3>Objective</h3> We aimed to clarify prognostic impact LGE CS. <h3>Methods</h3> Before start therapy, 43 consecutive LGE-positive were divided into two groups based on by a median value: small-extent...
We aimed to use contrast-enhanced cardiac magnetic resonance (CE-CMR) imaging elucidate the prevalence of left ventricular (LV) thrombus in patients suspected embolic stroke undetermined source (ESUS) with previous myocardial infarction or LV dysfunction (LV ejection fraction [LVEF] <50%).We prospectively investigated 797 consecutive who presented our hospital acute ischemic between 2014 and 2015. Patients LVEF<50% underwent CE-CMR imaging. ESUS was diagnosed according proposal criteria...
Intracerebral hemorrhage (ICH) and cerebral microbleeds (CMB) in autosomal dominant arteriopathy with subcortical infarcts leukoencephalopathy are more common East Asian populations than people of white European ancestry. We hypothesized that the ethnic difference is explained by Asian-specific NOTCH3 p.R75P mutation.
To preoperatively evaluate anatomic variations of the bronchial arteries by obtaining three-dimensional (3D) simulations with multidetector computed tomography (CT).This study was approved institutional review board, and written informed consent obtained from all participants. Seventy-three consecutive patients esophageal cancer underwent dynamic CT. The data were used to generate 3D thoracic cavity. These images then bilateral mediastinal course in relation esophagus trachea-bronchi....
Early detection of hemorrhagic transformation after reperfusion therapy is crucial in acute stroke treatment. Here, we evaluated the relationship between and post-reperfusion hyperperfusion using pulsed arterial spin labeling (ASL) perfusion MRI 123 I-iodoamphetamine single-photon emission-computed tomography. Patients who developed showed significantly higher cerebral blood flow affected lesion thrombolysis and/or endovascular intervention. Focal (ipsilateral to contralateral ratio >1.5)...
<h3>Objective</h3> To determine safety and efficacy of cardiac rehabilitation (CR) initiated immediately following balloon pulmonary angioplasty (BPA) in patients with inoperable chronic thromboembolic hypertension (CTEPH) who presented continuing exercise intolerance symptoms on effort even after a course BPA; 2–8 sessions/patient. <h3>Methods</h3> Forty-one consecutive CTEPH underwent their final BPA improved resting mean arterial pressure 24.7±5.5 mm Hg suffered remaining were...
Background: The aim of this study was to investigate whether the combination QRS duration ≥120 ms (wide [wQRS]) and late gadolinium enhancement (LGE) is a precise prognostic indicator for dilated cardiomyopathy. Methods Results: We investigated association between LGE plus wQRS primary end point (all-cause death) composite sudden cardiac death (SCD) or aborted SCD in 531 patients with also analyzed these points among class I indication implantable cardioverter defibrillator implantation....
Basal thinning of the interventricular septum (IVS) is an important diagnostic feature cardiac sarcoidosis (CS), but its long-term prognostic significance remains unclear.We examined 74 consecutive patients who were diagnosed with CS. IVS thickness at a point located 10 mm from aortic annulus was measured. left ventricular minor axis level also measured according to recommended procedure American Society Echocardiography. Patients divided into 2 groups based on presence or absence basal...
Abstract Aims To investigate the clinical impact of T1 mapping for detecting myocardial impairment in takotsubo cardiomyopathy (TTC) over time. Methods and results In 23 patients with apical ballooning type TTC, following 3T magnetic resonance (MR) examinations were performed at baseline 3 months after TTC onset: T2-weighted imaging, T2 mapping, native extracellular volume fraction (ECV), late gadolinium enhancement. Eight healthy controls underwent same MR examinations. Serial...
Background To improve myocardial delayed enhancement (MDE) CT, a deep learning (DL)-based post hoc denoising method supervised with averaged MDE CT data was developed. Purpose assess the image quality of denoised images and evaluate their diagnostic performance by using late gadolinium (LGE) MRI as reference. Materials methods obtained averaging three acquisitions single breath hold 5 minutes after contrast material injection in patients from July 2020 to October 2021 were retrospectively...
Introduction: Oral carriage of Streptococcus mutans (the main pathogen dental caries), positive for cnm that encodes the collagen-binding protein Cnm, is associated with development hypertensive intracerebral hemorrhage and increase cerebral microbleeds (CMBs) in our retrospective observational studies. Herein, we prospectively investigated a relationship between Cnm-expressing S. CMBs longitudinal multicenter cohort study. Methods: We initiated multicenter, prospective study (RAMESSES: R...
Background: Pulmonary vein isolation (PVI) is a cornerstone of catheter ablation in patients with paroxysmal atrial fibrillation, and balloon-based has been recently performed worldwide. The second-generation cryoballoon (CB2) proven to be highly effective achieving freedom from fibrillation. However, there are some debatable questions, including the ideal number freeze cycles. Methods: AD-Balloon study (Multicenter Study Validity Additional Freeze Cycles for Cryoballoon Ablation) was...
Abstract Aims Myocardial fibrosis of the left ventricle (LV) is a prognostic factor in dilated cardiomyopathy (DCM). This study aims to evaluate whether right ventricular (RV) endomyocardial biopsy (EMB) can predict degree LV beforehand DCM. Methods and results Fibrosis extent 70 RV‐EMB specimens DCM diagnosis was compared with that whole cross‐sectional excised hearts same patients (52 explanted for transplant 18 autopsied hearts). The median interval between excision 4.1 (0.13–19.3) years....
Convexity subarachnoid hemorrhage (cSAH), defined as intrasulcal bleeding restricted to hemispheric convexities, has several etiologies: reversible cerebral vasoconstriction syndrome, amyloid angiopathy, and internal carotid artery (ICA) stenosis or occlusion. However, it remains unknown whether dissection causes cSAH.We retrospectively investigated patients admitted our hospital between 2005 2013 with ischemic stroke transient attack caused by dissection. Cerebral was diagnosed cervical...
Coronary high-intensity plaques (HIPs) with a high plaque-to-myocardial signal intensity ratio (PMR) on non-contrast T1-weighted imaging in patients stable coronary artery disease (CAD) are associated future events. To characterize the morphological substrate of HIP, we performed correlative optical coherence tomography (OCT) study.We examined 137 lesions 105 angina pectoris or silent myocardial ischaemia scheduled for percutaneous intervention (PCI) using 3 T magnetic resonance scanner....