- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Atrial Fibrillation Management and Outcomes
- Cardiac Structural Anomalies and Repair
- Sarcoidosis and Beryllium Toxicity Research
- Neurological disorders and treatments
- Cardiomyopathy and Myosin Studies
- ECG Monitoring and Analysis
- Cardiovascular Syncope and Autonomic Disorders
- Cardiovascular Effects of Exercise
- Viral Infections and Immunology Research
- Pulmonary Hypertension Research and Treatments
- Ion channel regulation and function
- Congenital Heart Disease Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Nuclear Structure and Function
- Health Systems, Economic Evaluations, Quality of Life
- Heart Failure Treatment and Management
- Infective Endocarditis Diagnosis and Management
- RNA Research and Splicing
- Neuroscience and Neural Engineering
- Muscle activation and electromyography studies
- Cerebrovascular and Carotid Artery Diseases
- Vascular anomalies and interventions
National Cerebral and Cardiovascular Center
2015-2025
RELX Group (United States)
2024
RELX Group (United Kingdom)
2024
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2021-2022
Vita-Salute San Raffaele University
2021-2022
Kumamoto University
2018-2021
San Raffaele University of Rome
2021
Tokyo Medical University Hachioji Medical Center
2006
General Hospital of Drama
1995
Mutations in LMNA (lamin A/C), which encodes lamin A and C, typically cause age-dependent cardiac phenotypes, including dilated cardiomyopathy, conduction disturbance, atrial fibrillation, malignant ventricular arrhythmias. Although the type of mutations have been reported to be associated with susceptibility arrhythmias, gene-based risk stratification for complications remains unexplored.The multicenter cohort included 77 mutation carriers from 45 families; disorders were retrospectively...
Epicardial unipolar mapping has not been thoroughly investigated in Brugada syndrome (BrS). To examine the characteristics of epicardial potentials BrS and investigate differences from overt cardiomyopathy. was performed 8 patients with 6 We J-wave amplitudes using recordings at delayed potential (DP) sites via bipolar recordings. The repolarization time (RT) around DP recording measured, maximum dispersion RT divided by distance defined as index (RTDI). baseline revealed significantly...
Diagnosis of cardiac sarcoidosis (CS) is sometimes difficult due to a low positive rate epithelioid granulomas by endomyocardial biopsy (EMB). Accordingly, Japanese guidelines can allow the CS diagnosis using clinical data alone without EMB results (clinical CS) since 2006. However, little known about prognosis and outcome CS.Purpose this study was analyze prognosis, outcomes, response corticosteroid large-scale cohort survey.Overall, 422 patients (mean age 60 ± 13 years, 68% female, median...
Background: Pulmonary vein isolation (PVI) is a cornerstone of catheter ablation in patients with paroxysmal atrial fibrillation, and balloon-based has been recently performed worldwide. The second-generation cryoballoon (CB2) proven to be highly effective achieving freedom from fibrillation. However, there are some debatable questions, including the ideal number freeze cycles. Methods: AD-Balloon study (Multicenter Study Validity Additional Freeze Cycles for Cryoballoon Ablation) was...
Background Aging is one of the major concerns and determinants indications for catheter ablation (CA) atrial fibrillation. This study aimed to assess safety CA in older patients with fibrillation undergoing CA. Methods Results The JROAD-DPC (Japanese Registry All Cardiac Vascular Diseases-Diagnosis Procedure Combination) a nationwide claims database using data from Japanese Diagnosis Combination/Per Diem Payment System. Among 6 632 484 records found between April 2012 March 2018 1058...
Background: The effect of paced-QRS (p-QRS) duration on long-term outcomes is unclear, so we assessed the association between p-QRS and cardiac events.
Background Ventricular parasystole is strongly associated with ventricular fibrillation (VF) in patients non-ischaemic cardiomyopathy. However, the relationship between and cardiac sarcoidosis (CS) remains unclear. The purpose of this study was to examine prevalence CS. Methods This a retrospective observational 214 consecutive diagnosed CS (mean age: 69±12 years, 104 males, median follow-up period: 6.8 years (IQR: 3.2–10.7) our centre. We investigated who developed arrhythmia (VA) using...
Mutation in the lamin A/C gene (LMNA) is associated with several cardiac phenotypes, such as conduction disorders (CCD), atrial arrhythmia (AA), malignant ventricular (MVA) and left dysfunction (LVD), leading to sudden death (SCD) and/or end-stage heart failure. We investigated how these phenotypes are each other which of them most important for total mortality. Methods Results: A multicenter registry included 110 LMNA mutation carriers (age, 43±15 years, male: 62%) from 60 families. After...
The prognosis and later fatal arrhythmia in cardiac sarcoidosis (CS) with relatively preserved function were unclear.This study aimed to evaluate the arrhythmic events patients CS mildly impaired function.Data collected from a nationwide Japanese cohort survey conducted 57 hospitals (n = 420); 322 left ventricular ejection fraction (LVEF) >35% investigated.Ventricular tachycardia (VT) manifestation was present 50 (16%) absent 272 (84%), of whom 36 (72%) 46 (17%), respectively, had an...
Abstract Introduction Infection is one of the most important complications associated with cardiac implantable electronic device (CIED) therapy. The number reports comparing outcomes transvenous lead extraction (TLE), surgical extraction, and conservative treatment for CIED infections using a real‐world database limited. This study investigated association between strategies their outcomes. Methods We performed retrospective analysis 3605 patients admitted to 681 hospitals nationwide...