A5077263123- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Chromosomal and Genetic Variations
- Genetic diversity and population structure
- Animal Behavior and Reproduction
- Animal Genetics and Reproduction
- Fish Biology and Ecology Studies
- Genomics and Phylogenetic Studies
- Amphibian and Reptile Biology
- Sperm and Testicular Function
- Reproductive biology and impacts on aquatic species
- Fish biology, ecology, and behavior
- Sexual Differentiation and Disorders
- Fish Ecology and Management Studies
- Turtle Biology and Conservation
- Peroxisome Proliferator-Activated Receptors
- Identification and Quantification in Food
- Genomics and Chromatin Dynamics
- Genetic Mapping and Diversity in Plants and Animals
- Aquaculture Nutrition and Growth
- Demographic Trends and Gender Preferences
- Evolution and Genetic Dynamics
- Adipose Tissue and Metabolism
- Physiological and biochemical adaptations
- Genomic variations and chromosomal abnormalities
- Genetic and phenotypic traits in livestock
University of Canberra
2016-2025
ACT Government
2014-2024
Hiroshima University
2021-2022
Kasetsart University
2016
La Trobe University
2016
Australian National University
2004-2015
Oeko Institut
2009
Harvard University
2008
University of Stirling
2002-2007
Sex chromosomes have evolved many times in animals and studying these replicate evolutionary "experiments" can help broaden our understanding of the general forces driving origin evolution sex chromosomes. However this plan study has been hindered by inability to identify chromosome systems large number species with cryptic, homomorphic Restriction site-associated DNA sequencing (RAD-seq) is a critical enabling technology that where traditional cytogenetic methods failed. Using newly...
Significance Genomes of birds and reptiles, but not mammals, consist a few large chromosomes many tiny microchromosomes. Microchromosomes are gene-rich highly conserved among reptiles share homology with one or more the an invertebrate that diverged from vertebrate lineage 684 Ma. interact strongly crowd together at center cells, suggesting functional coherence. Many microchromosomes have been lost independently in turtles, snakes, lizards as they fused each other larger chromosomes. In...
Sex in reptiles is determined by genes on sex chromosomes or incubation temperature. Previously these two modes were thought to be distinct, yet we show that high temperatures reverse genotypic males (ZZ) phenotypic females a lizard with ZZ and ZW chromosomes. Thus, the W chromosome not necessary for female differentiation. determination probably via dosage-sensitive male-determining gene Z inactivated extreme temperatures. Our data invite novel hypothesis evolution of temperature-dependent...
The cloning and characterization of cDNAs genes encoding three peroxisome proliferator-activated receptor (PPAR) isotypes from two species marine fish, the plaice (Pleuronectes platessa) gilthead sea bream (Sparus aurata), are reported for first time. Although differences in genomic organization fish PPAR compared with their mammalian counterparts evident, sequence alignments phylogenetic comparisons show to be homologs PPARalpha, PPARbeta/delta, PPARgamma. Like homologs, PPARs bind a...
Sex in many organisms is a dichotomous phenotype--individuals are either male or female. The molecular pathways underlying sex determination governed by the genetic contribution of parents to zygote, environment which zygote develops interaction two, depending on species. Systems multiple interacting influences continuously varying influence (such as temperature) determines outcome have at least one threshold. We show that when viewed threshold trait, evolution can permit novel transitions...
Abstract Most of snakes exhibit a ZZ/ZW sex chromosome system, with different stages degeneration. However, undifferentiated chromosomes and unique Y sex-linked markers, suggest that an XY system has also evolved in ancestral lineages. Comparative cytogenetic mappings revealed several genes share ancestry among X, Z chromosomes, implying ZW may have undergone transitions during serpent’s evolution. In this study, we performed comparative analysis to identify homologies across (Henophidia)...
The diversity of sex chromosomes among amniotes is the product independent evolution different systems in lineages, defined by novel sex-determining genes. Convergent very common, suggesting that some genes are particularly adept at taking on a role. Comparative gene mapping, and more recently whole genome sequencing, have now turned up other surprising relationships; regions amniote become determining taxa seem to share synteny, or sequence, others. Is this, after all, evidence these were...
The extent to which sex reversal is associated with transitions in determining systems (XX-XY, ZZ-ZW, etc.) or abnormal sexual differentiation predominantly unexplored amphibians. This large part because most amphibian taxa have homomorphic chromosomes, has traditionally made it challenging identify discordance between phenotypic and genetic amphibians, despite all amphibians having a component determination. Recent advances molecular techniques such as genome complexity reduction high...
Transitions between sex determination systems have occurred in many lineages of squamates and it follows that novel chromosomes will also arisen multiple times. The formation may be reinforced by inhibition recombination the accumulation repetitive DNA sequences. karyotypes monitor lizards are known to highly conserved yet this family not been fully investigated. Here, we compare male female three Australian lizards, Varanus acanthurus, V. gouldii rosenbergi, from two different clades....
Sex determination systems are exceptionally diverse and have undergone multiple independent evolutionary transitions among species, particularly reptiles. However, the mechanisms underlying these not been established. Here, we tested for differences in sex-linked markers only known reptile that is polymorphic sex system, spotted snow skink, Niveoscincus ocellatus, to quantify genomic accompanied this transition. In a highland population, determined genetically, whereas lowland offspring...
<title>Abstract</title> Varanids are known for conserved sex chromosomes, but there differences in the size of W chromosome among species representing varying stages evolution. We tested homology ZW system with varanids four from two lineages Australia, Odatria and Gouldii. found that while DNA sequences chromosomes we tested, also identified a homologous region on an enlarged autosomal microchromosome shares some isolated populations <italic>V. acanthurus</italic> citrinus</italic> lineage....