A5086512872- Legume Nitrogen Fixing Symbiosis
- Genomics and Phylogenetic Studies
- Plant Disease Resistance and Genetics
- Soybean genetics and cultivation
- Chromosomal and Genetic Variations
- Plant responses to water stress
- Plant Pathogens and Resistance
- Microbial Community Ecology and Physiology
- Genomics and Chromatin Dynamics
- CRISPR and Genetic Engineering
- Parasites and Host Interactions
- Helminth infection and control
- Plant tissue culture and regeneration
- Plant Gene Expression Analysis
- Plant pathogens and resistance mechanisms
- Plant Pathogens and Fungal Diseases
- Plant Molecular Biology Research
- Microbial Metabolic Engineering and Bioproduction
- RNA and protein synthesis mechanisms
- Agronomic Practices and Intercropping Systems
- Plant Physiology and Cultivation Studies
- Genetic and Environmental Crop Studies
- Pasture and Agricultural Systems
- Lipid metabolism and biosynthesis
- Plant-Microbe Interactions and Immunity
The University of Western Australia
2016-2025
Punjabi University
2023
The Kids Research Institute Australia
2017-2018
Commonwealth Scientific and Industrial Research Organisation
2016
Indian Institute of Technology Jodhpur
2014
Gian Sagar Medical College and Hospital
2012
We investigated genome folding across the eukaryotic tree of life. find two types three-dimensional (3D) architectures at chromosome scale. Each type appears and disappears repeatedly during evolution. The architecture that an organism exhibits correlates with absence condensin II subunits. Moreover, depletion converts human to a state resembling seen in organisms such as fungi or mosquitoes. In this state, centromeres cluster together nucleoli, heterochromatin domains merge. propose...
Significance Genomes of birds and reptiles, but not mammals, consist a few large chromosomes many tiny microchromosomes. Microchromosomes are gene-rich highly conserved among reptiles share homology with one or more the an invertebrate that diverged from vertebrate lineage 684 Ma. interact strongly crowd together at center cells, suggesting functional coherence. Many microchromosomes have been lost independently in turtles, snakes, lizards as they fused each other larger chromosomes. In...
Respiratory viral infections, particularly those caused by rhinovirus, exacerbate chronic respiratory inflammatory diseases such as asthma and obstructive pulmonary disease (COPD). Airway epithelial cells are the primary site of rhinovirus replication responsible initiating host immune response to infection. Numerous studies have reported that anti-viral innate (including type I III interferon) in is less effective or deficient leading conclusion immunity a key determinant severity during...
Abstract Fouling of maritime infrastructure is pervasive due to abundant biological and chemical activity within the oceanic environment. Marine biofilms their successional growths are prevalent issues in biofouling, but current industrial research-based analyses often do not provide a holistic view fouling biodiversity. Cathodic protection longstanding system safeguarding from corrosive marine environment, limited studies on interactions between growth cathodic have been conducted context...
Early detection of SARS-CoV-2 infection is key to managing the current global pandemic, as evidence shows virus most contagious on or before symptom onset. Here, we introduce a low-cost, high-throughput method for diagnosing and studying infection. Dubbed Pathogen-Oriented Low-Cost Assembly & Re-Sequencing (POLAR), this amplifies entirety genome. This contrasts with typical RT-PCR-based diagnostic tests, which amplify only few loci. To achieve goal, combine enrichment developed by ARTIC...
Abstract Constructed wetlands (CWs) are engineered environments designed to utilise natural processes treat urban or industrial wastewater, with the core driver of bioremediation process provided by microorganisms present within. This study isolated 32 bacterial strains from sediment across Sardar Bherry CW find candidates remediation properties and understand how physiochemical gradient wastewater input influences functional bacteria present. Bacterial isolates recovered closer effluence...
Analyses of ancient DNA typically involve sequencing the surviving short oligonucleotides and aligning to genome assemblies from related, modern species. Here, we report that skin a female woolly mammoth (†Mammuthus primigenius) died 52,000 years ago retained its architecture. We use PaleoHi-C map chromatin contacts assemble genome, yielding 28 chromosome-length scaffolds. Chromosome territories, compartments, loops, Barr bodies, inactive X chromosome (Xi) superdomains persist. The active...
Subterranean clover (Trifolium subterraneum L.) is the most widely sown annual pasture legume species in southern Australia, valued livestock and grains industries as a source of high-quality forage for its ability to fix atmospheric nitrogen. From initial accidental introduction into Australia 19th Century subsequent commercialisation early 1900s, 45 cultivars have been registered Australia. These consist 32 ssp. subterraneum, eight yanninicum, five brachycalycinum range flowering time from...
Diverse signaling pathways are activated by perturbation of mitochondrial function under different growth conditions.Mitochondria have emerged as an important organelle for sensing and coping with stress in addition to being the sites metabolic pathways. Here, responses moderate light drought were examined Arabidopsis (Arabidopsis thaliana) mutant plants lacking a functional alternative oxidase (alternative oxidase1a [aox1a]), those reduced cytochrome electron transport chain capacity (T3/T7...
Phenotypic variation among species is a product of evolutionary changes to developmental programs
Abstract Early detection of infection with SARS-CoV-2 is key to managing the current global pandemic, as evidence shows virus most contagious on or before symptom onset. Here, we introduce a low-cost, high-throughput method for diagnosing and studying infection. Dubbed Pathogen-Oriented Low-Cost Assembly & Re-Sequencing (POLAR), this amplifies entirety genome. This contrasts typical RT-PCR-based diagnostic tests, which amplify only few loci. To achieve goal, combine enrichment developed...
The fungal species belonging to the genus Trichoderma has been globally recognized as a potential candidate of biofertilizer and biocontrol agent prevent devastating soil-borne pathogens enhance growth productivity agricultural crops. antagonistic activity pathogenic fungi is attributed several mechanisms including antibiosis enzymatic hydrolysis, which are largely associated with wide range metabolites secreted by species. Besides suppressing target pathogens, produced may act against...
Urogenital schistosomiasis is caused by the blood fluke Schistosoma haematobium and one of most neglected tropical diseases worldwide, afflicting > 100 million people. It characterised granulomata, fibrosis calcification in urogenital tissues, can lead to increased susceptibility HIV/AIDS squamous cell carcinoma bladder. To complement available treatment programs break transmission disease, sound knowledge understanding biology ecology S. required. Hybridisation/introgression events...
Narrow-leafed lupin (NLL; Lupinus angustifolius) is a key rotational crop for sustainable farming systems, whose grain high in protein content. It gluten-free, non-genetically modified, alternative source to soybean (Glycine max) and as such has gained interest human food ingredient. Here, we present chromosome-length reference genome the species pan-genome assembly comprising 55 NLL lines, including Australian European cultivars, breeding lines wild accessions. We core variable genes report...
Abstract Background The Australian black swan ( Cygnus atratus ) is an iconic species with contrasting plumage to that of the closely related northern hemisphere white swans. relative geographic isolation may have resulted in a limited immune repertoire and increased susceptibility infectious diseases, notably diseases from which Australia has been largely shielded. Unlike mallard ducks mute olor ), extremely sensitive highly pathogenic avian influenza. Understanding this impaired by absence...
Biofloc technology aims to maximize fish farming productivity by effectively breaking down ammonia and nitrite, promoting healthy flocculation, enhancing the growth immunity of cultured animals. However, a major limitation in this field is suitable starter microbial culture narrow number species that have been tested with biofloc system. Here, we investigated various inoculum containing beneficial microbes probiotics, immunostimulatory flocs development bioremediation properties would lead...
Freshwater ecosystems and their biota are under increasing pressure from anthropogenic stressors. In response to declining fish stocks, hatchery stocking programmes widely implemented as core components of restoration management strategies, with positive outcomes for some wild populations. Despite this, remains contentious due potential genetic ecological risks Monitoring evaluation critical ensuring the long-term sustainability populations, but identification stocked individuals...
Significant improvements in sequencing technologies have allowed the development of more contiguous genome assemblies many plant species. The pea is characterized by its richness repeated elements and long complex centromeres. This makes assembly challenging. In this paper, we present an improved version sequence French cultivar Cameor. was obtained combining Nanopore PacBio long-read sequencing, Hi-C contact maps Bionano maps. centromeres refined using a combination FISH ultra-long read...
Rhizoctonia solaniis an important root infecting pathogen of a range food staples worldwide including wheat, rice, maize, soybean, potato and others. Conventional resistance breeding strategies are hindered by the absence tractable genetic in any crop host. Understanding biology pathogenicity mechanisms this fungus is for addressing these disease issues, however, little known about howR. solanicauses disease. This study capitalizes on recent genomic studies applying mass spectrometry based...