Afraa Mohammad

ORCID: 0000-0003-4765-6501
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About
Contact & Profiles
Research Areas
  • HIV Research and Treatment
  • Neuroinflammation and Neurodegeneration Mechanisms
  • HIV-related health complications and treatments
  • COVID-19 epidemiological studies
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Trypanosoma species research and implications
  • Research on Leishmaniasis Studies
  • Software-Defined Networks and 5G
  • CAR-T cell therapy research
  • Alzheimer's disease research and treatments
  • S100 Proteins and Annexins
  • Advanced Computing and Algorithms
  • HIV/AIDS Research and Interventions
  • Biosimilars and Bioanalytical Methods
  • Cytokine Signaling Pathways and Interactions
  • IoT and Edge/Fog Computing
  • Brain Tumor Detection and Classification
  • Antimicrobial Peptides and Activities
  • HIV/AIDS drug development and treatment
  • Endometriosis Research and Treatment
  • Biomedical Ethics and Regulation

Shiraz University
2025

National Research Center for Hematology Russian Academy of Medical Sciences
2024

Health Research and Educational Trust
2023

Moscow Institute of Physics and Technology
2021-2022

Kazan Federal University
2022

Kazan State Medical Academy
2022

Physico-Technical Institute
2022

University of Cincinnati
2018-2020

University of Cincinnati Medical Center
2018-2020

Cincinnati Children's Hospital Medical Center
2020

HIV associated neurocognitive disorders cause significant morbidity and mortality despite the advent of highly active antiretroviral therapy. A deeper understanding fundamental mechanisms underlying infection pathogenesis in central nervous system is warranted. Microglia are resident myeloid cells brain that readily infected by may constitute a CNS reservoir. We evaluated two microglial model cell lines (C20, HMC3) sources primary cell-derived microglia (monocyte-derived [MMG] induced...

10.1186/s12977-020-00544-y article EN cc-by Retrovirology 2020-11-19

During the ongoing coronavirus disease 2019 (COVID-19) pandemic, many individuals were infected with and have cleared virus, developing virus-specific antibodies effector/memory T cells. An important unanswered question is what levels of T-cell antibody responses are sufficient to protect from infection.

10.1093/cid/ciac278 article EN cc-by-nc-nd Clinical Infectious Diseases 2022-04-12

Summary Rapid spread of COVID-19 pandemic made a substantial share the world population immunised by SARS-CoV-2 antigens. Infection induces development virus-specific antibodies and T cells. Ample evidence on antibody-mediated protection is contrasted elusive role cells in preventing infection. To explore impact to quantify protective levels immune responses we conducted large prospective study: 5,340 Moscow residents were evaluated for antibody cellular monitored up 300 days. The tightly...

10.1101/2021.08.19.21262278 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2021-08-22

Abstract Background: HIV associated neurocognitive disorders cause significant morbidity and mortality despite the advent of highly active antiretroviral therapy. A deeper understanding fundamental mechanisms underlying infection pathogenesis in central nervous system is warranted. Microglia are resident myeloid cells brain that readily infected by may constitute a CNS reservoir. We evaluated two microglial model cell lines (C20, HMC3) sources primary cell-derived microglia (monocyte-derived...

10.21203/rs.3.rs-41442/v2 preprint EN cc-by Research Square (Research Square) 2020-10-15

Abstract Background: HIV associated neurocognitive disorders cause significant morbidity and mortality despite the advent of highly active antiretroviral therapy. A deeper understanding fundamental mechanisms underlying infection pathogenesis in central nervous system is warranted. Microglia are resident myeloid cells brain that readily infected by may constitute a CNS reservoir. We evaluated two microglial model cell lines (C20, HMC3) sources primary cell-derived microglia (monocyte-derived...

10.21203/rs.3.rs-41442/v1 preprint EN cc-by Research Square (Research Square) 2020-07-17

Introduction: Endometriosis is a prevalent, benign, estrogen-dependent, chronic gynecological disorder associated with pelvic pain and infertility. Despite its prevalence impact on reproductive health, the underlying molecular mechanisms differential protein expression patterns different disease severity levels remain poorly understood. Key components such as extracellular matrix (ECM) (laminins, fibronectins), adhesion molecules, cytokines, growth factors have been shown to contribute...

10.33425/2639-9342.1236 article EN Gynecology & Reproductive Health 2023-10-31

Formyl peptide receptors (FPRs) are an important part of innate immunity involved in antimicrobial phagocyte functions such as chemotaxis, secretory degranulation, and respiratory burst. These responses observed both acute systemic chronic inflammation. Abundant or constant release pro-inflammatory ligands leads to the pre-activation phagocytes when subsequent stimulation induces more intense cellular response. Binding formyl receptor with its agonist activates production reactive oxygen...

10.15789/1563-0625-eaf-2503 article EN cc-by Medical Immunology (Russia) 2022-12-08
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