A5001515709- Meningioma and schwannoma management
- Vascular Malformations Diagnosis and Treatment
- Pituitary Gland Disorders and Treatments
- Neurofibromatosis and Schwannoma Cases
- Glioma Diagnosis and Treatment
- Adrenal and Paraganglionic Tumors
- Growth Hormone and Insulin-like Growth Factors
- Neuroendocrine Tumor Research Advances
- Cancer Genomics and Diagnostics
- CRISPR and Genetic Engineering
- Advanced Neuroimaging Techniques and Applications
- Vestibular and auditory disorders
- Brain Metastases and Treatment
- RNA modifications and cancer
Beijing Tian Tan Hospital
2019-2024
Capital Medical University
2019-2024
BACKGROUND AND OBJECTIVES: Lineage-based classification has critical clinical implications in pituitary neuroendocrine tumor (PitNET). As the most prevalent subtype of multilineage PitNET, PitNET originating from both pituitary-specific positive transcription factor 1 (Pit1) and steroidogenic factor-1 (SF1) lineages (Pit1/SF1-adenoma) is expected to exhibit rich varied behaviors. A comprehensive understanding pathological characteristics Pit1/SF1-adenoma will provide mechanistic insight...
There are few published data concerning pituitary adenomas (PAs) derived from multiple lineages. In this study the authors aimed to determine clinicopathological characteristics and prognostic profiles of PAs with cell lineage combinations (PAwMCs).The reviewed on 723 patients who had undergone surgery between 2018 2021 identified 93 cases (12.9%) PAwMC. They collected detailed these cases, including clinical information, pathological features, prognosis. From among 589 only one (PAwOCs),...
Cognitive dysfunction accompanied by neurofibromatosis type 1 is one of the significant characteristics this neurocutaneous disorder and has a serious impact on patients' quality life. Although studies cognitive function in children with have revealed that attentional impairment key deficit these patients, few examined their neuropsychological profile, especially whether also abnormal specific adult patients 1. In study, we used revised attention network test to examine three...
Background: Cognitive dysfunction is one of the main symptoms neurofibromatosis type 1 (NF1). As an important cognitive function, working memory (WM) has rarely been systematically analyzed in NF1 by isolating particular domain WM, and existing data involving WM adult patients with are insufficient. This study aimed to investigate characteristics different types from perspective population. Method: We comprehensively both verbal visuospatial domains using N-back task (including task) 31...
Despite pituitary neuroendocrine tumor (PitNET) being extra-axial tumors without direct damage to brain tissue, patients with PitNET exhibit neuropsychological impairments. However, it remains unclear whether there are differences between and intra-axial that directly destroy the parenchyma. This prospective study aims clarify this distinction inform decision-making for intracranial of diverse origins.
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Background: Neurofibromatosis type 2 (NF2) is a rare genetic syndrome that predisposes individuals to develop bilateral vestibular schwannomas (VSs) causing high risk of life-threatening neurological complications. Traditional treatment options for NF2-associated VS usually cause damage, and date, there are no FDA-approved pharmacotherapies NF2. The aim this study was evaluate the antitumor efficacy Qu-Du-San-Jie (QDSJ) decoction, traditional Chinese medicine formula, on investigate...
Abstract Purpose Cognitive dysfunction is one of the main symptoms neurofibromatosis type 1 (NF1). As an important advanced cognitive function, working memory (WM) has rarely been systematically analyzed in NF1 by isolating particular domain WM, and existing data involving WM adults with are controversial. This study aimed to clarify characteristics from perspective adult population. Methods We comprehensively both verbal visuospatial domains using N-back task (including task) 31 34 healthy...