A5027281614- Dementia and Cognitive Impairment Research
- Suicide and Self-Harm Studies
- Functional Brain Connectivity Studies
- Heart Rate Variability and Autonomic Control
- Mental Health Research Topics
- Cardiovascular and exercise physiology
- Cardiac Health and Mental Health
- Psychosomatic Disorders and Their Treatments
- Traumatic Brain Injury Research
- Physical Activity and Health
- Sleep and related disorders
- Schizophrenia research and treatment
- Sleep and Wakefulness Research
- Eating Disorders and Behaviors
- Health and Well-being Studies
- Transcranial Magnetic Stimulation Studies
- Treatment of Major Depression
- Diet and metabolism studies
- Blood Pressure and Hypertension Studies
- Frailty in Older Adults
- Cancer-related cognitive impairment studies
- Older Adults Driving Studies
- Menopause: Health Impacts and Treatments
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Aging and Gerontology Research
University of Pittsburgh
2014-2025
University of Illinois Urbana-Champaign
2017-2025
Cornell University
2025
McLean Hospital
2025
Mayo Clinic in Florida
2025
The University of Texas Health Science Center at San Antonio
2025
University of Illinois Chicago
2025
University of Pittsburgh Medical Center
2022-2024
GTx (United States)
2022
VA Pittsburgh Healthcare System
2019-2021
Evidence regarding the nature and prevalence of 24-hour activity pattern phenotypes in older adults, especially those related to depression symptoms cognition, is needed guide development targeted mechanism research behavioral interventions.To identify subgroups adults with similar rhythm characteristics characterize associated cognitive performance.From January March 2022, a cross-sectional analysis 2011-2014 National Health Nutrition Examination Survey (NHANES) accelerometer study was...
Introduction Disruptions in estrogen exposure (i.e., surgically induced menopause) have been linked to poorer cognitive aging and dementia risk. Hormone therapy use (e.g., birth control, menopausal hormone therapy) has shown mixed associations with performance, possibly due limited test batteries. To address previous inconsistencies, we investigated baseline data from Investigating Gains Neurocognition an Intervention Trial of Exercise (IGNITE). We hypothesized that (1) oophorectomy prior...
Abstract Background Consumer wearable devices could, in theory, provide sufficient accelerometer data for measuring the 24-hour sleep/wake risk factors dementia that have been identified prior research. To our knowledge, no study older adults has demonstrated feasibility and acceptability of accessing consumer to compute rhythm measures. Objective We aimed establish characterizing measures using gathered from Apple Watch with without mild cognitive impairment (MCI), examine correlations...
Abstract Introduction Sleep disturbances are linked to suicidal ideation and depression in older adults. Depression is also contemplation of suicide behavior. While there complex, bi-directional relationships between sleep, depression, risk, these have yet be measured well-defined risk groups late life. This study explored the association sleep using actigraphy digital diaries via a 3-week ecological momentary assessment protocol. Methods Participants included 72 adults (M±SD=65.3± 6.5...
Objective Cognitive impairment has been associated with late‐life suicidal behavior. Without longitudinal data it is unclear whether these are transient features of a depressive state or stable impairments. We examined longitudinally the course cognitive in older adults depression and history suicide attempt. Methods investigated persistence over time 198 depressed (age >60); 91 attempters, 39 individuals ideation (ideators), 68 non‐suicidal assessed 2‐year period at four points. used...
(1) Examine the role of exercise intensity on mental health symptoms in a community-based sample older adults. (2) Explore moderating genetic variation brain-derived neurotrophic factor (BDNF) and apolipoprotein E (APOE) effects symptoms. This study is secondary analysis three-arm randomized controlled trial, comparing 6 months high-intensity aerobic training vs. moderate-intensity no-contact control group assessed using Depression, Anxiety, Stress Scale (DASS). The BDNF Val66Met...
Abstract Technology-assisted cognitive-behavioral therapy (CBT) interventions have been conducted for symptoms including depression, pain, and fatigue in patients with chronic illnesses but not end-stage renal disease (ESRD). The purpose of this study was to pilot the feasibility acceptability a technology-assisted CBT intervention ESRD on hemodialysis (HD), share design implementation lessons learned, provide preliminary results changes select patient-reported symptoms. This single-center...
Physical activity (PA) is important for maintaining health throughout the lifespan. However, adherence to PA regimens poor with approximately 50% of older adults terminating intervention programs within 6 months. In this study, we tested whether gray matter volume and white microstructural integrity before initiation a predicts adherence.One hundred fifty-nine aged 60 80 years were randomly assigned moderate-intensity aerobic walking condition or nonaerobic stretching toning condition....
The aim of this study was to identify factors associated with acceptability and efficacy yoga training (YT) for improving cognitive dysfunction in individuals schizophrenia (SZ).We analysed data from two published clinical trials YT among Indians SZ: (1) a 21-day randomised controlled trial (RCT, N = 286), 3 6 months follow-up (2) open (n 62). Multivariate analyses were conducted examine the association baseline characteristics (age, sex, socio-economic status, educational duration, severity...
The increasing proportion of older adults in the population is expected to lead an increased prevalence age-related diseases, including cognitive decline and impairment. It imperative find affordable effective methods for improving brain function throughout life span. Research reviewed this article suggests that physical activity exercise have potential taking advantage capacity plasticity late adulthood. Promising evidence from studies examining effect on health indicates need further research area.
An inaugural workshop supported by "The Leo and Anne Albert Charitable Trust," was held October 4-7, 2019 in Scottsdale, Arizona, to focus on the effects of exercise brain discuss how physical activity may prevent or delay onset aging-related neurodegenerative conditions. The Scientific Program Committee (led Dr. Jeff Burns) assembled translational, clinical, basic scientists who research various aspects body brain, with overall goal gaining a better understanding as diseases. In particular,...