- Neonatal and fetal brain pathology
- Heart Rate Variability and Autonomic Control
- Neuroscience of respiration and sleep
- Ovarian cancer diagnosis and treatment
- Pregnancy and preeclampsia studies
- Non-Invasive Vital Sign Monitoring
- Pelvic floor disorders treatments
- Preterm Birth and Chorioamnionitis
- Gestational Diabetes Research and Management
- Systemic Lupus Erythematosus Research
- Endometrial and Cervical Cancer Treatments
- Gut microbiota and health
- Uterine Myomas and Treatments
- Phonocardiography and Auscultation Techniques
- Ureteral procedures and complications
- Urinary Bladder and Prostate Research
- Blood properties and coagulation
- Renin-Angiotensin System Studies
- Estrogen and related hormone effects
- Erythrocyte Function and Pathophysiology
- Prenatal Screening and Diagnostics
- ECG Monitoring and Analysis
- Pregnancy-related medical research
- Maternal and fetal healthcare
- Urological Disorders and Treatments
Hanyang University
2013-2025
Hanyang University Seoul Hospital
2011-2023
University of California, Irvine
2009-2010
Hanyang University Medical Center
2010
Wonkwang University
2007
Wonkwang University Medical Center
2006
High-risk infants are usually treated with empirical antibiotics after birth, regardless of the evidence infection; however, their gut microbiome and metabolome have seldom been studied. This study investigated influence antibiotic exposure on associated metabolic pathways in term preterm infants. Thirty-six within 10 days birth who were admitted to a neonatal intensive care unit/newborn nursery unit divided into four groups based maturity (gestational age) use antibiotics. Genomic DNA was...
This study aimed to evaluate the difference in gut microbiomes between preterm and term infants using third-generation long-read sequencing (Oxford Nanopore Technologies, ONT) compared with an established gold standard, Illumina (second-generation short-read sequencing). A total of 69 fecal samples from 51 (T) (P) were collected at 7 28 days life. Gut colonization profiling was performed by 16S rRNA gene ONT. We used validate compare patterns 13 neonates. Using bioinformatic analysis, we...
Background and Objective:We conducted this study to evaluate the feasibility efficacy of immediate laparoscopic nontransvesical repair without omental interposition for vesicovaginal fistula (VVF) developing after total abdominal hysterectomy (TAH), which causes not only social economic misery patient but also considerable stress physicians who perform surgery.Methods:We performed a retrospective review 5 women underwent VVFs, TAH from October 2007 March 2009. In terms procedure, cystoscopy...
Accurate measurement of bladder volume is an important tool for evaluating function. In this study, we propose a wearable scanner system that can continuously measure in daily life urinary patients who need urodynamic studies. The consisted 2-D array, which included integrated forward-looking piezoelectric transducers with thin substrates. This study aims to estimate the using small number transducers. A least-squares method was implemented optimize ellipsoid quadratic surface equation...
Covalent adduction of a nitrosyl group to cysteines [S-nitrosylation (S-NO)] is emerging as key route for nitric oxide (NO) directly modulate protein functions. Here, we studied the effects estrogens on endothelial S-NO and analyzed nitrosyl-proteomes by biotin/CyDye switch technique combined with two-dimensional fluorescence difference gel electrophoresis identified nitrosoproteins matrix-assisted laser desorption/ionization-time flight mass spectrometry. Estradiol-17beta (E2) rapidly...
There is little follow-up data in preterm infants from mothers with systemic lupus erythematosus (SLE). The aim of this study was to determine maternal outcomes and compare neonatal term born SLE.This a prospective tertiary medical care center clinical research for rheumatoid arthritis. Demographic data, features, laboratory findings, treatment complications 77 pregnant SLE patients were prospectively evaluated 2007 2013.Ninety-two (44 males 48 females including four sets twins) enrolled....
Background: In Korea, the breastfeeding (BF) rate of infants aged 6 months or more is drastically decreasing, and this phenomenon particularly worrisome for future health population.The present study aimed to identify an antenatal strategy initiation continuation human BF, how Baby-Friendly Hospitals (BFHs) may positively influence intention breastfeed.Methods: A total 414 pregnant Korean women were surveyed using questionnaires determine current knowledge benefits breast milk, whether they...
Abstract The objectives of this study were to provide new parameters better understand labor curves, and a model predict the time full cervical dilation (CD). We studied curves using retrospective records 594 nulliparas, including at term, spontaneous onset, singleton vertex deliveries normal birth weight infants. redefined Friedman's curve, applied three‐parameter curve with logistic genetic algorithm Newton–Raphson method necessary reach CD. is more effective than for modeling progress, as...
Aims: We studied how linear and nonlinear heart rate dynamics differ between normal fetuses (n=135) uncomplicated small-for-gestational age (SGA) (n=65), aged 32–40 weeks' gestation.
Directed methods for differentiating human embryonic stem cells (hESCs) into dopaminergic (DA) precursor using stromal co-culture systems are already well established. However, not all of the hESCs differentiate DA precursors these methods. HSF6, H1, H7, and H9 precursors, but CHA13 CHA15 hardly differentiate. To overcome this problem, we modified differentiation system to include a co-culturing step that exposes noggin early in process. This was done γ-irradiated noggin-overexpressing...
Abstract Aim: The purpose of the present study was to compare and analyze differences in antepartal fetal heart rate (FHR) parameters during pregnancy outcomes normal fetuses with nuchal cord (NC). Material Methods: We surveyed all non‐stress test (NST) data acquired using a computerized FHR analysis system at Hanyang University Hospital between 2005 2008, selected 150 cases that had NC. NSTs were performed 37 42 weeks gestation. Subjects divided into three groups by number NCs: no NC ( n =...
To examine how complex and irregular fetal heart rate (FHR) dynamics differ between fetuses of normal pregnancies those complicated by maternal anemia (MA), to place this in the context high-risk pregnancies.Our study population consisted 97 pregnant women affected MA, 118 pregnancy-induced hypertension (PIH), 88 gestational diabetes mellitus (GDM), 53 with preterm premature rupture membranes (pPROM), 356 as controls. We calculated approximate entropy (ApEn), sample (SampEn), correlation...
(1) Background: Non-invasive uroflowmetry is used in clinical practice for diagnosing lower urinary tract symptoms (LUTS) and the health status of a patient. To establish smart system measuring flowrate during urination without any temporospatial constraints patients with disorder, acoustic signatures from uroflow being treated LUTS at tertiary hospital were utilized. (2) Methods: Uroflowmetry data collected construction verification long short-term memory (LSTM) deep-learning algorithm. The...
A growing body of evidence suggests an association between a higher maternal pre-pregnancy mass index (BMI) and adverse long-term neurodevelopmental outcomes for their offspring. Despite recent attention to the effects obesity on fetal neonatal brain development, changes in microstructure preterm infants born mothers with are still not well understood. This study aimed detect obese offspring as using diffusion tensor imaging (DTI).A total 32 (born 16 normal BMI high BMI) at <32 weeks...
This study was conducted to assess the relative significance of amplitude versus duration accelerations in non-stress test (NST) analysis. A total 3055 normal fetal heart rate (FHR) tracings at 30–42 weeks' gestation were analyzed by automated FHR analyzing software. Accelerations classified as one four combinations and duration: 15 bpm–15 seconds (Acc15–15), bpm–10 (Acc15–10), 10 (Acc10–15) (Acc10–10). We estimated correlation among acceleration using analysis based on linear regression...
A 29-year-old woman presented with secondary amenorrhea, primary infertility, and virilization, which had developed over the past 2 years was suspected to have a virilizing tumor at her left ovary. Her serum testosterone level markedly elevated (380 ng/dL). Left salpingoophorectomy performed, histopathological examination revealed thecoma of The postoperative returned 65 ng/dL. patient did not regression virilism soon. However, normal menstruation 29 days after surgery gave birth baby 13...