A5004948530- Asymmetric Hydrogenation and Catalysis
- Catalytic C–H Functionalization Methods
- Carbon dioxide utilization in catalysis
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Catalytic Cross-Coupling Reactions
- Organoboron and organosilicon chemistry
- Molecular Sensors and Ion Detection
- CO2 Reduction Techniques and Catalysts
- Gamma-ray bursts and supernovae
- Organometallic Complex Synthesis and Catalysis
- Electrocatalysts for Energy Conversion
- Metal-Organic Frameworks: Synthesis and Applications
- Sulfur Compounds in Biology
- Cyclopropane Reaction Mechanisms
- Advanced Photocatalysis Techniques
- Catalytic Processes in Materials Science
- Lanthanide and Transition Metal Complexes
- Crystallography and molecular interactions
- Catalytic Alkyne Reactions
- Nanomaterials for catalytic reactions
- Magnetism in coordination complexes
- Solid State Laser Technologies
- Luminescence and Fluorescent Materials
- Photorefractive and Nonlinear Optics
Shandong Normal University
2016-2025
South China Normal University
2024
Guangxi University
2024
Fudan University
2024
State Key Laboratory of Medical Neurobiology
2024
Purdue University West Lafayette
2024
Affiliated Hospital of Southwest Medical University
2023
First Affiliated Hospital of Sichuan Medical University
2023
National Research Council Canada
2018-2023
Zhejiang Sci-Tech University
2020-2022
Changes in adenosine triphosphate (ATP) and peroxynitrite (ONOO–) concentrations have been correlated a number of diseases including ischemia-reperfusion injury drug-induced liver injury. Herein, we report the development fluorescent probe ATP-LW, which enables simultaneous detection ONOO– ATP. selectively oxidizes boronate pinacol ester ATP-LW to afford 4-hydroxy-1,8-naphthalimide product NA-OH (λex = 450 nm, λem 562 nm or λex 488 568 nm). In contrast, binding ATP induces spirolactam ring...
A single-atom Ce-modified α-Fe2O3 catalyst (Fe0.93Ce0.07Ox with 7% atomic percentage of Ce) was synthesized by a citric acid-assisted sol-gel method, which exhibited excellent performance for selective catalytic reduction NOx NH3 (NH3-SCR) over wide operating temperature window. Remarkably, it maintained ∼93% NO conversion efficiency 168 h in the presence 200 ppm SO2 and 5 vol % H2O at 250 °C. The structural characterizations suggested that introduction Ce leads to generation local Fe-O-Ce...
The effectiveness of surface synergetic oxygen vacancy (SSOV) on a catalyst has been proposed in the selective reduction NO to N2 by CO. In this work, we prepared fresh CuMn2O4 spinel using freeze-assisted sol–gel method, and then engineered SSOVs through CO pretreatment (CO–CuMn2O4) at 250 °C. catalytic performance CO–CuMn2O4 showed significant improvement, attributed presence SSOVs, comparison that sample. Additionally, our findings elucidated limited reactivity vacancies (SOVs) single...
A density functional theory study at the M05-2X(IEFPCM, THF)/6-311+G**//M05-2X/6-31G* level has been conducted to gain insight into catalytic mechanism of first metal-free N-heterocyclic carbene (NHC)-catalyzed conversion carbon dioxide methanol. Among various examined reaction pathways, we found that most favorable leads experimentally detected intermediates, including formoxysilane (FOS), bis(silyl)acetal (BSA), silylmethoxide (SMO), and disiloxane (DSO). However, our also revealed...
The mechanistic details of nickel-catalyzed reduction CO(2) with catecholborane (HBcat) have been studied by DFT calculations. nickel pincer hydride complex ({2,6-C(6)H(3)(OP(t)Bu(2))(2)}NiH = [Ni]H) has shown to catalyze the sequential from HCOOBcat, then CH(2)O, and finally CH(3)OBcat. Each process is accomplished a two-step sequence at center: insertion C═O bond into [Ni]H, followed reaction product HBcat. Calculations predicted difficulties observing possible intermediates such as...
Density functional theory calculations have been performed to investigate the mechanism of reactions amines with primary alcohols produce amides, catalyzed by pincer complex Ru(II)-PNN (PNN = 2-(di-tert-butylphosphinomethyl)-6-diethylaminomethyl)pyridine). The results lead us propose a catalytic cycle that includes four stages: (stage I) alcohol dehydrogenation aldehyde, II) coupling aldehyde amine form hemiaminal, III) hemiaminal amide, and IV) catalyst regeneration via H2 elimination trans...
Here we report the synthesis and screening of Cy-3-NO2 that showed simultaneous fluorescence sensing ability towards glutathione cysteine under single excitation, its application in living cell imaging.
We demonstrate a new small molecule fluorescent probe, possessing near-infrared (NIR) emission and an unusually large Stokes shift. It can be readily taken up by live cells mitochondria, track subtle pH changes with effectively reduced biological background fluorescence improved measurement accuracy.
Hydrogen peroxide (H2O2) as a reactive oxygen species (ROS) plays crucial role in oxidative stress and signal transduction of organisms. Currently, fluorescence probe has proven to be powerful tool for the H2O2 analysis. However, common problem is slow response, causing difficulty tracking situ. Herein, we describe novel aggregation-induced emission (AIE) based on increased polarity C-B bonds that well suited monitoring rapidly selectively. Importantly, was successfully applied visualize...
(S)-2-(2-Chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetonitrile ((S)-CIK) is a key intermediate in the synthesis of (S)-clopidogrel, which one most saleable worldwide antiplatelet and antithrombotic drugs. We show herein facile method for direct (S)-CIK via Strecker reaction using homochiral covalent framework catalyst heterogeneous way. The asymmetric involves photothermal-conversion-triggered, thermally driven affords 98% yield with 94% enantiomeric excess under...
Abstract Eukaryotic five-methylcytosine (m 5 C) is an important regulator of viral RNA splicing, stability, and translation. However, its role in HBV replication remains largely unknown. In this study, functional m C sites are identified hepatitis B virus (HBV) mRNA. The modification at nt 1291 not only indispensable for Aly/REF export factor (ALYREF) recognition to promote mRNA HBx translation but also the inhibition RIG-I binding suppress interferon-β (IFN-β) production. Moreover, NOP2/Sun...
Development of efficient dehydrogenation/hydrogenation is critical to the realization organic hydride hydrogen storage. Using B3LYP DFT calculations, we have investigated catalytic mechanisms reversible 3qu4h/4qu (3qu4h = tetrahydroquinoline and 4qu quinoline) catalyzed by Ir-complex 2cat (Cp*IrPYD′, Cp* η5-C5Me5 PYD′ CF3-substituted 2-pyridonate), reported Yamaguchi Fujita et al. Two reactive species (7bif 12hcl) are identified play important roles in system. The (7bif) with bifunctional...
A series of 2-(1-arylimino)ethyl-9-arylimino-5,6,7,8-tetrahydrocycloheptapyridine derivatives was synthesized and fully characterized, thereafter reacted with iron dichloride to form their corresponding iron(II) complexes. The single crystals representative organic complex compounds were obtained analyzed by the X-ray diffraction analysis, indicating distorted bipyramidal geometry around core. Moreover, DFT calculations performed on selected species determine structural features. On...
A novel approach for the synthesis of a variety polysubstituted trans-2,3-dihydropyrroles from wide range chalcones and β-enamine ketones (esters) via iodine-promoted tandem Michael/cyclization sequence has been developed, affording desired products in moderate to excellent yields. This methodology is highly efficient, convenient way access functionalized 2,3-dihydropyrroles readily accessible substrates under mild reaction conditions.
The 9-aryliminocycloheptapyridyl nickel chlorides, activated by Et<sub>3</sub>Al<sub>2</sub>Cl<sub>3</sub> or MAO, exhibited high activities toward ethylene polymerization and produced highly branched PE in narrow polydispersity.
A series of 2-(1-aryliminoethyl)-9-arylimino-5,6,7,8-tetrahydrocycloheptapyridylcobalt chlorides were synthesized and characterized using FT-IR elemental analysis, the molecular structures complexes , confirmed to present a pseudo-square-pyramidal or trigonal-bipyramidal geometry around cobalt center single-crystal X-ray diffraction. Upon activation with either methylaluminoxane (MAO) modified (MMAO), all precatalysts gave high activities up level 10(7) gPE mol(-1) (Co) h(-1) toward ethylene...
Abstract The availability of a range excited states has endowed low dimensional quantum nanostructures with interesting luminescence properties. However, the origin photoluminescence emission is still not fully understood, which limited its practical application. Here we judiciously manipulate delicate surface ligand interactions at nanoscale interface single metal nanocluster, superlattice, and mesoporous materials. resulting interplay various noncovalent leads to precise modulation colors...
Abstract Atherosclerosis is a lipoprotein‐driven disease, and there no effective therapy to reverse atherosclerosis or existing plaques. Therefore, it urgently necessary create noninvasive reliable approach for early detection prevent initial plaque formation. intimately associated with inflammation, which accompanied by an excess of reactive oxygen species (ROS), leading cells requiring more glutathione (GSH) resist severe oxidative stress. the GSH‐hydrolyzed protein γ ‐glutamyl...
Electrochemical carbon dioxide reduction (ECO2RR) shows great potential to create high-value carbon-based chemicals, while designing advanced catalysts at the atomic level remains challenging. The ECO2RR performance is largely dependent on catalyst microelectronic structure that can be effectively modulated through surface defect engineering. Here, we provide an atmosphere-assisted low-temperature calcination strategy prepare a series of single-atomic Cu/ceria with varied oxygen vacancy...
There has been an increasing interest in developing efficient AAD (acceptorless alcohol dehydrogenation) catalysts, because of their potential applications atom economic synthesis, H2 production from biomass or its fermentation products (mainly alcohols), and the development organic hydride hydrogen storage systems. Using B3LYP DFT calculations with solvation effects accounted by SMD solvent model, we have investigated catalytic mechanism a novel Ir catalyst (2cat) dehydrogenation...
Density functional theory computations have been applied to gain insight into the CO2 reduction CH4 with Et3SiH, catalyzed by ammonium hydridoborate 1 ([TMPH](+)[HB(C6F5)3](-), where TMP = 2,2,6,6-tetramethylpiperidine) and B(C6F5)3. The study shows that is activated through concerted transfer of H(δ+) H(δ-) CO2, giving a complex (IM2) well-formed HCOOH entity, followed breaking O-H bond entity return TMP, resulting in an intermediate 2 ([TMPH](+)[HC(═O)OB(C6F5)3)](-)), being inserted B-H 1....
In order to investigate the Na<sub>2</sub>SeO<sub>3</sub>anticancer mechanism in HepG2 cells, a novel selenol fluorescence probe has been designed and used image selenocysteine (Sec) living cells and<italic>in vivo.</italic>
Finely tuned cobalt complexes, upon activation with either MAO or MMAO, exhibited high activities up to 80 °C and produced highly linear vinyl-polyethylenes.