A5065096839- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gallbladder and Bile Duct Disorders
- Pancreatic and Hepatic Oncology Research
- Coronary Interventions and Diagnostics
- Gastric Cancer Management and Outcomes
- Pediatric Hepatobiliary Diseases and Treatments
- Esophageal Cancer Research and Treatment
- Esophageal and GI Pathology
- Cardiac Valve Diseases and Treatments
- Liver physiology and pathology
- Antiplatelet Therapy and Cardiovascular Diseases
- Neuroblastoma Research and Treatments
- Oral and Maxillofacial Pathology
- Acute Myocardial Infarction Research
- Lipoproteins and Cardiovascular Health
- Lung Cancer Diagnosis and Treatment
- Gastrointestinal Tumor Research and Treatment
- Learning Styles and Cognitive Differences
- Peripheral Artery Disease Management
- Cardiac Imaging and Diagnostics
- Cardiac, Anesthesia and Surgical Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Anorectal Disease Treatments and Outcomes
- Evaluation of Teaching Practices
- Aortic Disease and Treatment Approaches
University of Liverpool
2015-2025
Norfolk and Norwich University Hospital
2009-2025
The University of Western Australia
2024
Royal Perth Hospital
2024
Aintree University Hospitals NHS Foundation Trust
2020-2024
Royal Liverpool University Hospital
2016-2024
University of Michigan
2023
Aintree University Hospital
2016-2022
University of East Anglia
2022
Queen Elizabeth Hospital Birmingham
2021-2022
Peptide receptor radionuclide therapy (PRRT) is an established treatment for patients with metastatic neuroendocrine tumours (NETs), although which factors are associated improved overall survival (OS) remains unclear. The primary aim of this study to determine what extent a radiological response (90)Y-DOTATOC/(90)Y-DOTATATE PRRT OS. association biochemical and clinical OS were assessed as secondary outcome measures.A retrospective analysis was conducted on 57 patients: classified using...
Perianal abscess is common. Traditionally, postoperative perianal cavities are managed with internal wound packing, a practice not supported by evidence. The aim of this randomized clinical trial (RCT) was to assess if non-packing less painful and it associated adverse outcomes.The Postoperative Packing Abscess Cavities (PPAC2) multicentre, RCT (two-group parallel design) adult participants admitted an NHS hospital for incision drainage primary abscess. Participants were 1:1 (via online...
Journal Article Validity of Self-Reported Smoking Status: Comparison Patients Admitted to Hospital with Acute Coronary Syndrome and the General Population Get access Jill P. Pell, Pell BHF Glasgow Cardiovascular Research Centre, University GlasgowGlasgow Correspondence: Room C214, Glasgow, G12 8TA, UK. Tel: +44 (0) 141 330 3473; Fax: 6955; E-mail: j.pell@clinmed.gla.ac.uk Search for other works by this author on: Oxford Academic PubMed Google Scholar Stuart M. Cobbe, Cobbe Sally J. Haw, Haw...
Abstract Objectives We aimed to investigate long-term survival of paclitaxel DCB for percutaneous coronary intervention (PCI). Background Safety concerns have been raised over the use devices peripheral artery disease recently, following a meta-analysis suggesting increased late mortality. With regard drug-coated balloon (DCB) angioplasty however, there is limited data date regarding possible mortality relating paclitaxel. Methods compared all-cause patients treated with those non-paclitaxel...
We aimed to investigate the safety of drug-coated balloon (DCB)-only angioplasty compared drug-eluting stent (DES), as part routine clinical practice.
ABSTRACT Background and Aims A randomized trial has previously demonstrated that neointimal modification with a scoring balloon improves the anti‐restenotic effect of drug‐coated (DCB) in patients drug‐eluting stent restenosis. There are very limited data about safety efficacy using balloons as part lesion preparation STEMI, especially de novo disease treated DCB‐only angioplasty. Methods We undertook an analysis SPARTAN Norwich Registry to address this question. compared composite endpoint...
Background: There are no data regarding the outcomes of patients with stent thrombosis (ST) being treated drug-coated balloon (DCB) angioplasty. Our aim was to compare ST DCB vs. a drug eluting (DES). Methods: In this registry analysis, we identified all for in our institution from June 2011 until November 2019. We excluded who died cath lab, uncrossable lesions, and thrombectomy only. Patient were obtained Hospital Episodes Statistics NHS England. The primary endpoint study composite...
Background and study aims:Adequate preoperative biliary drainage (PBD) is recommended in most patients with resectable perihilar cholangiocarcinoma (pCCA).Most expert centers use endoscopic plastic stents rather than selfexpanding metal (SEMS).In the palliative setting, however, of SEMS has shown longer patency superior survival.The aim this retrospective was to compare stent dysfunction versus for PBD pCCA patients. Patients methods:In retrospective, multicenter, international cohort study,...
There is limited published evidence on duodenal carcinoma due to its rarity. This study aimed evaluate gastric outlet obstruction and obstructive jaundice along with pathological variables as survival factors in patients adenocarcinoma following resection. Survival factor analysis was undertaken undergoing cancer surgery from 1997 2015 a single centre. were 57 of whom 18 had 14 jaundice. Fifty-three partial pancreatoduodenectomy four palliative bypass. Perioperative mortality morbidity 4%...
Abstract Peri-hilar cholangiocarcinoma (pCCA) is chemorefractory and limited genomic analyses have been undertaken in Western idiopathic disease. We undertook comprehensive of a U.K. pCCA cohort to characterize its mutational profile identify new targets. Whole exome targeted DNA sequencing was performed on forty-two resected tumors normal bile ducts, with Gene Set Enrichment Analysis (GSEA) using one-tailed testing generate false discovery rates (FDR). 60% patients harbored one...
Background: Ascites is common in cirrhosis but uncommon after liver transplant. We aimed to characterize the incidence, natural history, and current management strategies of post-transplant ascites. Methods: performed a retrospective cohort study patients who underwent transplantation at 2 centers. included deceased donor whole graft transplants between 2002 2019. Chart review identified with ascites, requiring paracentesis 1 6-month post-transplants. Detailed chart clinical transplant...
Journal Article Variation in treatment of intrahepatic cholangiocarcinoma: a nationwide multicentre study Get access Jane McClements, McClements Department HPB Surgery, Nottingham University Hospitals NHS Trust, Nottingham, UK Search for other works by this author on: Oxford Academic Google Scholar Juan W Valle, Valle Oncology, Christie Foundation Manchester, https://orcid.org/0000-0002-1999-0863 Lauren Blackburn, Blackburn Adam Brooks, Brooks Andreas Prachalias, Prachalias Surgery and...