A5042039600- Reproductive Biology and Fertility
- Sperm and Testicular Function
- Effects and risks of endocrine disrupting chemicals
- Ovarian function and disorders
- Mesenchymal stem cell research
- Reproductive System and Pregnancy
- Selenium in Biological Systems
- Immunotoxicology and immune responses
- RNA Interference and Gene Delivery
- Retinoids in leukemia and cellular processes
- Nigella sativa pharmacological applications
- Bone Tissue Engineering Materials
- Pluripotent Stem Cells Research
- Reproductive Health and Technologies
- Pesticide Exposure and Toxicity
- Neurogenesis and neuroplasticity mechanisms
- Electrospun Nanofibers in Biomedical Applications
- Toxic Organic Pollutants Impact
- Carcinogens and Genotoxicity Assessment
- Arsenic contamination and mitigation
- Heavy Metal Exposure and Toxicity
- Ginkgo biloba and Cashew Applications
- Curcumin's Biomedical Applications
- Natural Antidiabetic Agents Studies
- Endometriosis Research and Treatment
Arak University
2016-2025
GTx (United States)
2019
Royan Institute
2014
Academic Center for Education, Culture and Research
2014
Arak University of Medical Sciences
2010
Ovarian tissue transplantation is performed to preserve fertility in patients undergoing chemotherapy and radiotherapy. However, ischemia/reperfusion (IR) injury free radical production occurring during the revascularization of transplanted are major limitations this procedure. The aim study was investigate effect erythropoietin (EPO) as an antioxidant on oxidative stress ovary survival following transplantation. Naval Medical Research Institute (NMRI) mice (4-5 weeks old) were divided into...
This experiment investigated the impact of serum from patients with type 2 diabetes mellitus on angiogenic behavior human mesenchymal stem cells in vitro. Changes level Ang-1, Ang-2, cell migration, and trans-differentiation into pericytes endothelial lineage were monitored after 7 days. The interaction evaluated using surface plasmon resonance technique. Paracrine restorative effect diabetic was tested pancreatic β cells. Compared to data FBS normal serum, reduced survival chemotaxis toward...
Polycystic ovary syndrome (PCOS) is associated with low-quality oocytes. The aim of the present study was to investigate effects metformin (MET), N-acetylcysteine (NAC) and their combination on follicular fluid parameters, oocytes embryo quality in PCOS patients. A prospective randomised placebo-controlled pilot 60 Iranian women (aged 25–35 years) undergoing intracytoplasmic sperm injection (ICSI) designed. Women were divided into four groups (n = 15 each): (1) an MET, administered 1500 mg...
Background: Dexamethasone (DEX) is a common medicine that capable of causing malformation in the male reproductive system. The aim this study was to investigate effect vitamin C (Vit-C) on spermatogenesis indexes and daily sperm production (DSP) adult mice treated with DEX. Methods: Male Naval Medical Research Institute (NMRI) were divided into four groups: Control, DEX (7 mg/kg/day), Vit-C (100 +Vit-C for 7 days intraperitoneal injection. Results: A significant increase mean levels serum...
This study was organized to see whether vitamin E, as a strong antioxidant, could affect the abnormalities of testis structure caused by para-nonylphenol (p-NP) during its development.A total 32 female Wistar rats after mating were divided into four groups (n = 8): control, E (100 mg kg -1 per day), p-NP (250 day) and + E. The treated from seventh day pregnancy till twenty-first day.After weaning, male pups same orally for 90 days.Finally, right fixed, processed, stained studied using...
Polycystic ovary syndrome (PCOS) is related to low levels of serum l-carnitine, which has antioxidant, anti-inflammatory and antiapoptotic properties. The aim this study was investigate the effect l-carnitine on folliculogenesis in mice following induction PCOS. PCOS induced by daily injections testosterone enanthate (1mg per 100g, s.c., for 35 days). NMRI (21 days old) were divided into four groups (n=6 group): Control, Control+l-carnitine, PCOS+l-carnitine. Mice treated with 500mgkg-1,...
Paranonylphenol (p-NP) is an environmental pollutant that causes oxidative stress. The purpose of this study was to evaluate the protective effect N-acetylcysteine (NAC) as antioxidant on sperm parameters and testis in mice after treatment with p-NP. Adult were randomly divided into four groups (n = 6, each group) including 1-control, 2- p-NP (250 mg kg-1 day-1 ), 3- NAC (150 ) 4- + NAC. After 35 days oral treatment, mean spermatogenic index (p < 0.02), count 0.01), daily production tail...
Bisphenol A (BPA), an environmental pollutant, can generate free radicals which damages the reproductive system. Vitamin C is antioxidant may prevent adverse effects of radicals.The aim was to investigate effect vitamin on ovary tissue in rats treated with BPA.In this experimental study, 24 female Wistar (200±20 gr) were randomly divided into 4 groups (n=6): control, BPA (60 µg/Kg/day), (150 mg/Kg/day) and + orally for 20 days. The left ovaries taken out, fixed processing studied using...
Cannabis Sativa is a multiuse herb in traditional medicine, its hydroalcoholic extract (10, 50, and 100 mg/kg) administered interaperitoneally for 14 consequent days to Wistar male rats resulted significant decrease progressive motility of sperm.Sperm count seminiferous tubules diameter decreased significantly comparison with control group.Also animal body weight doses 50 mg/kg was observed.Changes testes serum testosterone were not significant.Cannabis sativa has negative effect on sperm...
Background: Fluoxetine (FLX), a selective serotonin reuptake inhibitor, is widely used in the treatment of neurological disorders. However, its application carries risk adverse reactions, including reproductive toxicities. Grape seed highly regarded for pharmacological activities, specifically antioxidant properties. Objectives: This study was designed to evaluate whether hydroalcoholic grape extract (GSE) could ameliorate FLX-evoked oxidative injuries mouse testis. Materials and Methods:...
The study has aimed to investigate the effect of Quercetin, as a potent antioxidant, on preventing negative effects freezing process sperm quality patients with Asthenospermia. Semen sample from 25 was randomly divided into three groups; fresh, control and Quercetin (50 μM). Seven days after freezing, samples were thawed at ambient temperature. Total motility, progressive normal morphology, viability DNA integrity evaluated according WHO criteria, Papanicolaou, eosin- nigrosine acridine...