A5038324795- Sports injuries and prevention
- Total Knee Arthroplasty Outcomes
- Knee injuries and reconstruction techniques
- Traumatic Brain Injury Research
- Tendon Structure and Treatment
- Shoulder Injury and Treatment
- Lower Extremity Biomechanics and Pathologies
- Foot and Ankle Surgery
- Orthopedic Surgery and Rehabilitation
- Osteoarthritis Treatment and Mechanisms
- Orthopaedic implants and arthroplasty
- Injury Epidemiology and Prevention
- Traumatic Brain Injury and Neurovascular Disturbances
- Trauma and Emergency Care Studies
- Cardiovascular Effects of Exercise
- Health and Medical Studies
- Cardiac Valve Diseases and Treatments
- Hip disorders and treatments
- Antifungal resistance and susceptibility
- Sociology and Education Studies
- Bone fractures and treatments
- Orthopedic Infections and Treatments
- Trauma Management and Diagnosis
- Periodontal Regeneration and Treatments
- Fungal Infections and Studies
University Hospital Regensburg
2016-2025
Philipps University of Marburg
2025
Klinikum Fulda
2025
Medical University of Vienna
2017-2024
Paderborn University
2022
Friedrich-Alexander-Universität Erlangen-Nürnberg
2016-2019
Heinrich Heine University Düsseldorf
2017
University of Regensburg
2016
National Center for Emerging and Zoonotic Infectious Diseases
2016
Centers for Disease Control and Prevention
2016
Hemophagocytic lymphohistiocytosis (HLH) causes multiple organ dysfunction frequently leading to intensive care unit (ICU) referral and/or death. We report on a series of critically ill adult patients treated with non-etoposide-based regimen including interleukin 1 antagonist anakinra, intravenous immunoglobulin (IVIG), corticosteroids (CS) for HLH.Eight (≥18 years) ICU having received treatment anakinra ± IVIG CS HLH between March 2014 and 2016 at large tertiary university hospital (Medical...
Transcatheter aortic valve implantation (TAVI) was developed as a promising new therapy for inoperable and surgical high-risk patients an alternative to traditional replacement. After successful procedure, prognosis may mainly be determined by comorbidities. However, no appropriate risk score predict long-term outcome following TAVI is currently available. The aim of this study identify predictors adverse short- outcomes. This two-centre registry including total 426 procedures (274...
Treatment of meniscus tears within the avascular region represents a significant challenge, particularly in situation early osteoarthritis. Cell-based tissue engineering approaches have shown promising results. However, studies not found consensus on appropriate autologous cell source clinical situation, specifically challenging degenerative environment. The present study sought to evaluate for meniscal repair demanding setting osteoarthritis.A rabbit model was used test repair. Bone marrow...
Background/Objectives: Patellar fractures are rare but clinically significant due to their impact on knee function. These injuries vary from simple transverse complex comminuted patterns. Computed tomography (CT) offers superior visualization compared radiographs, enabling accurate classification and surgical planning. This study utilized CT-based fracture mapping analyze patterns evaluate the of age, trauma-center level, AO/OTA classification. Methods: retrospective included 237 patients...
Avascular meniscus tears show poor intrinsic regenerative potential. Thus, lesions within this area predispose the patient to developing knee osteoarthritis. Current research focuses on approaches using growth factors or mesenchymal stem cells (MSCs) enhance healing capacity avascular zone. The use of MSCs especially as progenitor and a source has shown promising results. However, present studies bone-marrow-derived BMSCs in two-step procedure, which is limiting transfer clinical praxis. So,...
Abstract Introduction Intracapsular femoral neck fractures are one of the most common in Germany. Nevertheless, epidemiology and treatment modalities not described comprehensively. For this reason, study highlights different age groups summarizes strategies within period from 2009 to 2019 based on nationwide data. Materials methods In retrospective cohort all cases intracapsular (ICD-10: S72.0) between Germany were analyzed with regard epidemiology, incidence treatment. Operation procedure...
Objectives The diagnosis of invasive Candida infection remains challenging due to tests with slow turnaround times or mediocre performance. T2MR is a new diagnostic tool. We investigated the accuracy T2Candida® panel (T2) in comparison blood culture (BC) and SeptiFast® (SF) for detection five different species among high-risk ICU patients suspected candidemia. Methods analysed samples collected from candidemia (177 138 patients) August 2018 April 2020. Blood were concurrently by BC, SF...
Injury data of professional soccer players obtained from media reports are frequently used in scientific research, but the accuracy such is still unclear.Injuries German first and second league were documented by continuously screening over one season (2015-2016). After season, validity media-reported injuries was anonymously analyzed team physicians 8 different clubs.A total 255 240 teams had been published online, which 146 confirmed doctors as correct, yielding a rate 57.3% injuries. In...
Subtrochanteric femur fractures (SFF) are uncommon, but have a high complication rate concerning non-union and mechanical complications. There is ongoing discussion about risk factors for delayed fracture healing after SFF. The purpose of this study was to evaluate potential SFF.This retrospective radio-morphometric case control compares 61 patients SFF in two groups (uncomplicated within 6 months postoperatively vs. union) radiographical properties. were analyzed the following parameter:...
Introduction: Pediatric polytrauma is a complex condition with unique characteristics and requirements for early clinical care. This study aimed to analyze the injury patterns, care, outcomes of pediatric patients in Level I trauma center. The focus was on evaluation between different age groups recognition injuries as potential factors influencing outcomes. Methods: A prospective cohort model (ISS ≥ 16) conducted over 13-year period, stratified by (Group A: 0–5 years; Group B: 6–10 C: 11–15...
Abstract Football is the only sport in which ball can be played with head. Therefore, compared to other team sports, head injuries are quite common. Headers and dreaded cause severe neurological impairments long‐term, but there still a lack of data on how often headers performed different levels occur. In prospective cohort study, all heading situations as well incidents propensity injury (critical incidents) 45 elite‐level international matches were analyzed using standardized video...
The objective of this paper is to validate two different numerical methods for noise prediction the H-Darrieus wind turbine using a complementary approach consisting experimental measurements and simulations. acoustic model scale rotor were performed in an anechoic tunnel. This data basis validation computational aeroacoustic Thereby, we have applied schemes hybrid methods. As usual approaches, flow field calculations are carried out separate software packages. For both time-dependent...
Focal early osteoarthritis (OA) or degenerative lesions account for 60% of treated cartilage defects each year. The current cell-based regenerative treatments have an increased failure rate treating compared to traumatic defects. Mesenchymal stem cells (MSCs) are alternative cell source OA defects, due their greater chondrogenic potential, chondrocytes. Low oxygen tension physioxia has been shown enhance MSC matrix content and could improve functional outcomes therapies. present...
On September 17, 2015, the Pennsylvania Department of Health (PADOH) notified CDC a cluster three potentially health care-associated mucormycete infections that occurred among solid organ transplant recipients during 12-month period at hospital A. 18, B reported it had identified an additional recipient with mucormycosis. Hospitals A and are part same care system connected by pedestrian bridge. PADOH requested CDC's assistance on-site investigation, which started on 22, to identify possible...
Therapy options for ruptured Achilles tendons need to take into account the right balance of timing, amount and intensity loading ensure a sufficient biomechanical resilience healing tendon on one hand, enable an adequate tensile stimulus other hand. However, data human after rupture during separate stages are unknown. Shear wave elastography is ultrasound technique that measures material elastic properties non-invasively, was proven have very good correlation studies. Taking advantage this...
Abstract Background Unicompartimental knee arthroplasty (UKA) is a promising and increasing application to treat unicompartimental osteoarthritis. However, revision numbers after UKA are unknown. Therefore, aim of this study was determine the nationwide burden by answering following questions: (1) How did procedures developed over last decade as function age gender? (2) high percentage due infection? (3) Which therapy strategy chosen for surgical treatment aseptic UKA? Methods Revision rates...
Abstract Introduction Heading is an integral part of football and frequent media reports previous studies about potential danger heading head trauma in fuelled discussions. Epidemiological data video analyses regarding headings situation associated injuries are still missing male adult professional football. Methods In a prospective cohort study the fourth German league, 100 official matches 2015–2016 season were assessed by analysis standardized protocol. situations concomitant...
The historical treatment options for partial anterior cruciate ligament (ACL) ruptures were conservative therapy or ACL reconstruction by injured bundle entire replacement. In awareness of the regenerative potential biologic agents such as mesenchymal stem cells platelet rich plasma (PRP), healing response technique was developed to preserve with better outcomes than therapy. Further improvement this seems be obtained additional application PRP products. Thus, aim study evaluate midterm...
Background Video analysis is one of the most commonly applied methods for analysing football injuries. Purpose The objective this study was to assess accuracy video recording head injuries in professional from official matches four highest men’s leagues Germany. Methods In cohort study, detected by means all over season (2017–18) were compared registered with German statutory accident insurance. Results Our yielded 359 287 players. comparison found our those insurance only a match 23.1% (n =...