A5015033478- Lipid Membrane Structure and Behavior
- Microfluidic and Bio-sensing Technologies
- Microbial Inactivation Methods
- Polysaccharides Composition and Applications
- Advanced Drug Delivery Systems
- Nanoparticle-Based Drug Delivery
- Hydrogels: synthesis, properties, applications
- Spectroscopy Techniques in Biomedical and Chemical Research
- Carbon Nanotubes in Composites
- Iron oxide chemistry and applications
- Nanoplatforms for cancer theranostics
- Sphingolipid Metabolism and Signaling
- Extraction and Separation Processes
- biodegradable polymer synthesis and properties
- Nanocomposite Films for Food Packaging
- Nanopore and Nanochannel Transport Studies
- Polysaccharides and Plant Cell Walls
- RNA Interference and Gene Delivery
- Minerals Flotation and Separation Techniques
- Characterization and Applications of Magnetic Nanoparticles
- Advancements in Transdermal Drug Delivery
Sapienza University of Rome
2016-2022
Multidisciplinary Digital Publishing Institute (Switzerland)
2019
Institute for the Chemistry of OrganoMetallic Compounds
2019
The natural sesquiterpene β-caryophyllene (CRY) has been highlighted to possess interesting pharmacological potentials, particularly due its chemopreventive and analgesic properties. However, the poor solubility of this in aqueous fluids can hinder uptake into cells, resulting inconstant responses biological systems, thus limiting application. Therefore, identifying a suitable pharmaceutical form for increasing CRY bioavailability represents an important requirement exploiting potential. In...
Recently, magnetic nanoparticles (MNPs) have been used to trigger drug release from magnetoliposomes through a magneto-nanomechanical approach, where the mechanical actuation of MNPs is enhance membrane permeability. This result can be effectively achieved with low intensity non-thermal alternating field (AMF), which, however, found rare clinic application. Therefore, different modality generating fields has now investigated. Specifically, ability intermittent signals generated by pulsed...
The increasing interest toward biocompatible nanotechnologies in medicine, combined with electric fields stimulation, is leading to the development of electro-sensitive smart systems for drug delivery applications. To this regard, recently use pulsed trigger release across phospholipid membranes liposomes has been numerically studied, a deeper understanding phenomena at molecular scale. Aim work give an experimental validation feasibility control from liposome vesicles, using nanosecond...
The increasing interest towards biocompatible nanotechnologies in medicine, combined with electric fields stimulation, is leading to the development of electro-sensitive smart systems for drug delivery applications. Common examples materials include phospholipids that can be used design nano-sized vesicles suitable external actuation. To this regard, recently use pulsed trigger release across phospholipid membranes has been numerically studied, a deeper understanding phenomena at molecular...
The electromagnetic fields application as a way to enhance biomedical techniques has recently drawn the attention of scientific community, together with possibility use biocompatible nanocarriers safely transport therapeutic substances along body. For this reason, microdosimetric studies represent fundamental tool deeply understand biological effects and improve drug delivery nanosystems methods. With regard, behaviour liposomes, vesicles bilayered membrane similar cell membrane, are often...
Radiofrequency (RF) signals as a way to remotely control smart drug delivery nanocarriers represent promising tool overcome traditional therapeutic issues, such overdosing agents with reduced efficacy and related side effects on healthy tissues, in order obtain targeted release near diseased cells. Aim of this work is provide deep investigation the possible effect sine wave RF signals, 100 kHz 10 MHz, applied non-uniform random distribution 142 liposomes, realistic model biocompatible...