A5016396597- Essential Oils and Antimicrobial Activity
- Phytochemicals and Antioxidant Activities
- Pomegranate: compositions and health benefits
- Advancements in Transdermal Drug Delivery
- Carbon dioxide utilization in catalysis
- Chemical Synthesis and Reactions
- Phytochemistry and Biological Activities
- Antioxidant Activity and Oxidative Stress
- Polysaccharides and Plant Cell Walls
- Polysaccharides Composition and Applications
- CO2 Reduction Techniques and Catalysts
- Advanced Drug Delivery Systems
- Edible Oils Quality and Analysis
- Fermentation and Sensory Analysis
- Advanced Chemical Sensor Technologies
- Garlic and Onion Studies
- Asymmetric Hydrogenation and Catalysis
- Phytochemical and Pharmacological Studies
- Hydrogels: synthesis, properties, applications
- Hops Chemistry and Applications
- Fatty Acid Research and Health
- Cholinesterase and Neurodegenerative Diseases
- Lipid Membrane Structure and Behavior
- Enzyme function and inhibition
- Insect Pest Control Strategies
Sapienza University of Rome
2016-2025
University of L'Aquila
1995
Due to renewed interest in the cultivation and production of Italian Cannabis sativa L., we proposed a multi-methodological approach explore chemically biologically both essential oil aromatic water this plant. We reported chemical composition terms cannabinoid content, volatile component, phenolic flavonoid pattern, color characteristics. Then, demonstrated ethnopharmacological relevance plant cultivated Italy as source antioxidant compounds toward large panel enzymes (pancreatic lipase,...
Prostatitis, a general term describing prostate inflammation, is common disease that could be sustained by bacterial or non-bacterial infectious agents. The efficacy of herbal extracts with antioxidant and anti-inflammatory effects for blunting the burden inflammation oxidative stress, possible improvements in clinical symptoms, under investigation. Pollen have been previously reported as promising agents managing symptoms related to prostatitis. aim present work was evaluate protective...
Goji berries are undoubtedly a source of potentially bioactive compounds but their phytochemical profile can vary depending on geographical origin, cultivar, and/or industrial processing. A rapid and cheap extraction the polyphenolic fraction from Lycium barbarum cultivars, applied after homogenization treatments, was combined with high-performance liquid chromatography (HPLC) analyses based two different methods. The obtained hydroalcoholic extracts, containing interesting secondary...
Pomegranate is receiving renewed commercial and scientific interest, therefore a deeper knowledge of the chemical composition fruits less studied varieties required. In this work, juices from arils decoctions mesocarp plus exocarp were prepared fifteen varieties. Samples submitted to High Performance Liquid Chromatography—Diode Array Detector–Mass Spectrometry, spectrophotometric colorimetric CIEL*a*b* analyses. Antioxidant, antiradical metal chelating properties, inhibitory activity against...
Industrial hemp is a multiuse crop that has been widely cultivated to produce fibers and nutrients. The capability of the essential oil (EO) from inflorescences as antimicrobial agent reported. However, literature data are still lacking about EO antiprotozoal efficacy in vivo. present study aims unravel this concern through evaluation EOs (2.5 mL/kg, intraperitoneally) three different cultivars, namely Futura 75, Carmagnola selezionata Eletta campana, mice intraperitoneally infected with...
The aim of this work was to develop and characterize nanocomposite thin films containing silver nanoparticles (AgNPs), as wound dressings antifungal materials, using a green process for the nanoparticles' synthesis single step procedure preparation films. To end, polyphenol-rich extracts obtained from kiwi peels, an agri-food industrial by-product, were used reducing agent nitrate salt. AgNPs let form within film-forming solution, which composed by low acyl gellan gum plasticizing (glycerol...
Two different produced and packaged commercial typologies of pomegranate juice were analyzed for their physicochemical, nutritional, biological properties. The effects classical pasteurization (PJ) high-pressure processing (HP), applied during the productive cycle, evaluated through several advanced analytical methods, such as CIEL*a*b* colorimetry, HPLC-DAD, DI-ESI-MS MS/MS, NMR analyses. Moreover, exerted activity two juices was monitored Total Phenolic Flavonoid Contents, antiradical,...
Thirty samples of powdered infant milk formulas containing polyunsaturated fatty acids (PUFAs) have been stored at four different temperatures (20, 28, 40 and 55 °C) periodically monitored for their malondialdehyde (MDA) content up to one year. MDA levels ranged between 250 350 ng/kg in sealed with a maximum 566 28 °C three weeks after opening original packages, previously maintained ten months 20 °C. Sample 40° were also submitted CIE (Commission Internationale de l'Eclairage) colorimetric...
This study was performed to evaluate the metabolite recovery from different extraction methods applied Thymus algeriensis aerial parts. A high-performance liquid chromatographic method using photodiode array detector with gradient elution has been developed and validated for simultaneous estimation of phenolic compounds in extracts their corresponding purified fractions. The experimental results show that microwave-assisted aqueous 15 min at 100 °C gave most phenolics-enriched extract,...
In this study, gellan gum (GG), a natural polysaccharide, was used to fabricate spherical porous beads suitable as sustained drug delivery systems for oral administration. GG cross-linked with calcium ions prepare polymeric beads. Rheological studies and preliminary experiments of preparation allowed identify the CaCl2 concentrations obtaining stable particles. were formed, through ionotropic gelation technique, without presence synthetic clay laponite. The resultant analyzed dimensions...
Pomegranate peel is a natural source of phenolics, claimed to possess healing properties, among which are antioxidant and antidiabetic. In the present study, an ethyl acetate extract, obtained by Soxhlet from Dente di Cavallo DC2 pomegranate (PGE) characterized contain 4% w/w ellagic acid, has been evaluated for its hypoglycemic, antiglycation, antioxidative cytoprotective in order provide possible evidence future nutraceutical applications. The α-amylase α-glucosidase enzyme inhibition,...
A comprehensive study on essential oil samples of Foeniculum vulgare Miller from Tarquinia (Italy) is reported. 24-h systematic steam distillation was performed different harvested applying extraction times. The GC-MS analysis the residue outcome showed o-cymene, α-phellandrene, α-pinene and estragole as major constituents. predominance continued presence o-cymene makes this fennel a rather unique chemotype. An evident correlation between antifungal activity phenological stage demonstrated....
An Italian certified Neem seed oil was characterized through the color analysis, HPLC phenolic fingerprint and preliminary evaluation of cytotoxicity profile against human macrophage (THP-1) cell line. Moreover, a wide screening its enzyme inhibitory profile, antimicrobial activity towards Helicobacter pylori, several Candida spp. Malassezia furfur strains antiprotozoal Plasmodium falciparum, Leishmania infantum tropica were performed. demonstrated low toxicity great efficacy tyrosinase...
Fully ripe fruits and mature leaves of Elaeagnus angustifolia were harvested analyzed by means analytical biological tests to better comprehend the chemical composition therapeutic/nutraceutical potential this plant. Fruits dried obtained powders study their color character (via headspace gas chromatography) describe profile. Subsequently, they submitted a chloroform–methanol extraction, hydroalcoholic extraction procedure assisted or not microwaves, an with supercritical CO2, ethanol as...
Inflammatory bowel diseases (IBDs) are chronic and multifactorial inflammatory conditions of the colonic mucosa (ulcerative colitis), characterized by increased unbalanced immune response to external stimuli. Garlic its bioactive constituents were reported exert various biological effects, including anti-inflammatory, antioxidant immunomodulatory activities. We aimed evaluate protective effects a hydroalcoholic (GHE) water (GWE) extract from Sicilian variety garlic, known as Nubia red on an...