A5102956436- Neonatal Respiratory Health Research
- Pediatric health and respiratory diseases
- Kawasaki Disease and Coronary Complications
- Congenital Heart Disease Studies
- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Congenital Diaphragmatic Hernia Studies
- Viral Infections and Immunology Research
- Human Health and Disease
- Respiratory viral infections research
- Immunodeficiency and Autoimmune Disorders
- Transplantation: Methods and Outcomes
- Coronary Artery Anomalies
- Cardiac, Anesthesia and Surgical Outcomes
- Congenital heart defects research
- Pneumocystis jirovecii pneumonia detection and treatment
- COVID-19 Clinical Research Studies
- Infant Nutrition and Health
- Cardiovascular Effects of Exercise
- Viral gastroenteritis research and epidemiology
- Takotsubo Cardiomyopathy and Associated Phenomena
- Inflammasome and immune disorders
- Pulmonary Hypertension Research and Treatments
- Diabetes and associated disorders
- COVID-19 Impact on Reproduction
Peoples' Friendship University of Russia
2015-2025
Infectious Clinical Hospital No. 1
2015
Bakulev Scientific Center for Cardiovascular Surgery Russian Academy of Medical Sciences
1993
The literature review presents data from a limited number of available studies conducted over the last two decades on immunological deficiency in congenital heart defects (CHDs), which is cause frequent infectious complications before and after cardiac surgery. Several based screenings at various levels indicate presence primary secondary immunodeficiency CHDs, particular about 13 genetic syndromes CHD combined with immunodeficiency. suggests greater severity disorders patients critical...
Mycoplasma pneumoniae ( M. pn. ), which is a well-known pathogen to cause atypical pneumonia, in 25% of cases can lead wide range extra-pulmonary symptoms, reflecting damage almost any organ or system (skin and mucous membranes, nervous, cardiovascular, gastrointestinal, urinary etc.). Aspecific syndrome -induced rash mucositis (MIRM) has been identified recently. Among the CNS manifestations associated with , acute postinfectious cerebellar ataxia worth mentioning. In this article we...
Coronavirus disease 2019 (COVID-19) in children most cases is asymptomatic or mild, and its severe late complication multisystem inflammatory syndrome (MIS-C). The aim of the study to find clinical, laboratory instrumental characteristics, description therapeutic tactics, including determination profile patients requiring Tocilizumab prescription outcomes MIS-C associated with COVID-19. Materials methods research: 245 aged 3 months – 17 years old were included pilot prospective multicenter...
Objective of the Review: on basis domestic and foreign conciliation documents results our own research, to present up-to- date information about a dangerous complication bronchopulmonary dysplasia - pulmonary hypertension. Key Points: hypertension is common dysplasia, which has antenatal, perinatal postnatal risk factors. The presence factors, respiratory failure, bronchial obstruction in child with for excluding by echocardiography, allows detect an increase pressure artery, indirect signs...
Literature review discusses questions of hemodynamic significance Patent Ductus Arte-riosus, methods its surgical and drug (non-surgical) treatment features in premature newborns.
Pulmonary hypertension and pulmonary heart are severe complications of broncho-pulmonary dysplasia, accompanied by poor prognosis high mortality. Based on Doppler echocardio-graphy in 100 children with bronchopulmonary the frequency de-velopment formation was determined. The risk factors for these mortality outcomes have been defined. quantitative evaluation informative value electro-cardiographic, radiographic, computer tomographic signs dysplasia performed. correspondence functional...
Incidence of infectious complications in children with congenital heart disease, especially cyanotic and complex defects, is higher than the population, which associated both hemodynamic immune disorders. Various types primary immunodeficiencies disease dependence disorders on morphology defect, severity circulatory failure arterial hypoxemia are described. The importance diagnosing immunological emphasized to reduce risk cardiac surgery, mortality improve outcomes surgical interventions for...
Pneumonia is the most frequent infectious intercurrent pathology in children with Congenital heart disease. It reason for forced postponement of life-saving cardiac surgery. Our fifteen years’ experience congenital disease and pneumonia during preoperative period, allows not only to predict course infants CHD but also provide an optimal algorithm diagnosis therapy reduce time convalescences preparation.
A.P. Prodeus, N.D. Odinayeva, S.V. Voronin, I.N. Zakharova, I.A. Tuzankina, N.N. Volodin, K.V. Zhdanov, A.N. Pampura, D.I. Sadykova, E.I. Kondratyeva, A.A. Korsunskiy, E.A. Degtyareva, Savostyanov, S.A. Trusova, A.Yu. Lobenskaya, Ye.S. Nikonova, A.S. Lebedeva, E.V. Loshkova, V.D. Denisova, A.G. Rumyantsev. Guidelines for routing, monitoring and management tactics of immunocompromised children at risk patients with congenital immune defects. Pediatria n.a. G.N. Speransky. 2024; 103 (6):...
The review based on literature data and the authors' own research substantiates necessity of immunoprophylaxis respiratory syncytial virus infection (RSVI) in children at risk using palivizumab. main current epidemiology RSVI, its consequences, burden globally Russian Federation are reflected. groups severe RSVI considered as indications for listed, peculiarities course them given. experience implementing program Moscow prerequisites year-round immunization presented. formation use clinical...
The study data of the last two decades on primary and secondary immunodeficiency in congenital heart defects (CHD) as a cause frequent infectious complications before after cardiac surgery are presented. Based screenings various levels, provided greater severity immunological disorders critical cyanotic CHD conotruncal compared with those septal stenotic defects. Violations were more often related to T-cell function immunoglobulin deficiency (especially IgG IgG4 subgroups). Various types...
Approximately 5–15% of children develop post-COVID-19 syndrome after SARS-CoV-2 infection, which manifests itself with various pathological symptoms for more than 12 weeks. Cardiovascular range from serious myocardial inflammation, manifestations essential hypertension to signs autonomic dysfunction a tendency hypersympathicotonia, negatively affects the quality life children. We report case subacute myocarditis in patient long-COVID low-symptomatic acute disease. This illustrates high...
The article presents the clinical effectiveness of complex etiopathogenic therapy rotavirus infection in children using a combination «Adiarin» — tannate gelatin, hyposmolar rehydration solution and probiotic containing lactobacilli LGG bifidobacteria BB-12. It was found that patients receiving innovative treatment, compared with who were on traditional therapy, fever significantly less frequent, its duration hospitalization time reduced by 2.4 days. In addition, acidosis pronounced this...
Aim. To summarize the existing literature data and to optimize protocols of anticoagulant therapy for Kawasaki syndrome. Methods. A review treatment results in 10 patients with syndrome, where an individual approach anticoagulation led a positive result, surgical was not required, is presented. Results. In 5 6 timely diagnosis according protocol, transient ectasia coronary arteries further normalization their size within 4-7 months follow up detected. one child on 12th day disease small...
Aim. Development of informative differential diagnostic criteria inflammatory myocardial involvement in young athletes. Methods. A total 163 athletes (swimmers, football players and sailing athletes) aged 9 to 24 years (mean age 14.74±0,23 years, SD=3.03) were examined. Complete clinical functional examination was performed. Remodeling the left ventricle studied accordance with R. Devereux (1992) B. Maron (2005) echocardiographic criteria. Myocardial morphometry results compared...
Цель. Оптимизировать тактику ведения детей с бронхолегочной дисплазией (БЛД), осложненной легочной гипертензией (ЛГ).Материал и методы. Обследованы 100 БЛД в возрасте от 1 мес до 3 лет. Тяжесть устанавливалась на основании степени кислородозависимости 36 нед постконцептуального возраста, или 56 сут жизни, при выписке. ЛГ диагностировалась значении систолического давления артерии (СДЛА)≥36 мм рт. ст. методом допплерхокардиографии, «легочным сердцем» считали дилятацию полости гипертрофию...
Цель. Оценка перспектив использования определения аутоантител в парах «мать-новорожденный ребенок» для прогнозирования риска реализации внутриутробной инфекции (ВУИ) и другой перинатальной патологии, включая патологию сердечно-сосудистой системы у новорожденных разработки индивидуальных программ профилактики.Материал методы. Материалом исследования послужили 40 пар ребенок», поступивших неонатальные отделения ГБУЗ «ДИКБ №6 ДЗМ». В программу обследования бы ли включены анамнестические,...
Neuroendocrine cell hyperplasia of infancy (NEHI) is an interstitial lung disease unknown etiology that develops in and manifests as persistent tachypnea syndrome. A highly informative scale for the clinical diagnosis NEHI CT lungs used to diagnos disease. The presence a typical picture allows be made. We present case patient diagnosed on basis diagnostics NEHI, complicated by protein-energy insufficiency, chronic respiratory failure II degree, who long-term home oxygen therapy.