A5034680647- Multilevel Inverters and Converters
- Sensorless Control of Electric Motors
- Magnetic Bearings and Levitation Dynamics
- Electric Motor Design and Analysis
- Advanced DC-DC Converters
- Microgrid Control and Optimization
- Autophagy in Disease and Therapy
- Machine Fault Diagnosis Techniques
- Energy Harvesting in Wireless Networks
- HVDC Systems and Fault Protection
- Wireless Power Transfer Systems
- Advanced Battery Technologies Research
- Endoplasmic Reticulum Stress and Disease
- Silicon Carbide Semiconductor Technologies
- Advanced Algorithms and Applications
- Mitochondrial Function and Pathology
- Islanding Detection in Power Systems
- Electric and Hybrid Vehicle Technologies
- Magnetic Properties and Applications
- Power Systems and Renewable Energy
- Adaptive Control of Nonlinear Systems
- Industrial Technology and Control Systems
- Electromagnetic Launch and Propulsion Technology
- Frequency Control in Power Systems
- Adipose Tissue and Metabolism
Tongji University
2014-2025
Jilin University
2012-2025
Shanghai Tunnel Engineering Rail Transit Design & Research Institute
2020-2024
Second Military Medical University
2023
Changhai Hospital
2023
China Railway Corporation
2023
Quanzhou Institute of Equipment Manufacturing Haixi Institute
2022
Chinese Academy of Sciences
2022
Huazhong University of Science and Technology
2015-2017
Tongji Hospital
2015-2017
Cholinergic dysfunction in Alzheimer's disease has been attributed to stress-induced increases acetylcholinesterase (AChE) activity. Interleukin-1 (IL-1) is overexpressed disease, and stress-related changes long-term potentiation, an ACh-related cerebral function, are triggered by interleukin-1. Microglial cultures (N9) synthesized released IL-1 response conditioned media obtained from glutamate-treated primary neuron or PC12 cells. This contained elevated levels of secreted β-amyloid...
Accumulation of reactive oxygen species (ROS) such as hydrogen peroxide (H2O2) is an oxidative stress response, which induced various defense mechanisms or programmed cell death (PCD). As one the major types PCD, autophagy has been observed in response to several anticancer drugs and demonstrated be responsible for death. To date, however, exact mechanism by ROS regulates still poorly understood. Thus, purposes this study were elucidate how H2O2 exerts its cytotoxic effects on malignant...
This report describes an integrated study on identification of potential markers for gastric cancer in patients' tissues and sera based on: (i) genome-scale transcriptomic analyses 80 paired cancer/reference (ii) computational prediction blood-secretory proteins supported by experimental validation. Our findings show that: 715 150 genes exhibit significantly differential expressions all cancers early-stage versus reference tissues, respectively; a substantial percentage the alteration is...
Androgen deprivation therapy (ADT) induces cellular senescence and tumor stasis, thus serving as the standard treatment for prostate cancer (PCa). However, continuous suppression of canonical androgen receptor signaling actually leads to switch from androgen-responsive growth androgen-independent growth, contributing "escape" this ADT-induced (AIS) and, subsequently, development castration-resistant (CRPC). Unfortunately, mechanism underlying phenomenon remains elusive. In study, we...
A multi-purpose balanced (MPB) transformer is proposed in this paper for electric railway applications. The MPB developed from impedance-matching (IM) transformers widely used China's systems. has three main functions: (1) it provides a symmetrical two-phase voltage of 27.5 kV overhead lines to power trains; (2) supplies three-phase 10.5 substations; and (3) can accommodate harmonic filter with improved factor reduced manufacturing cost. In paper, the operating principles are elaborated,...
Significance Calcium overload has been recognized as a critical cause of the injury tissues suffer after periods ischemia. The ports that determine calcium entry into subjected to transient hypoxia have not identified. Here we identify two members potential receptor channel (TRPC) family nonselective cation channels allow passage calcium, TRPC3 and TRPC6, major factors causing in heart, which is responsible for ischemia/reperfusion (I/R) injury. Blocking TRPC activity or genetic ablation...
The mechanisms underlying cisplatin resistance in tumors are not fully understood. Previous studies have reported that cellular to oxidative stress is accompanied by cisplatin. However, the relationship between and drug human ovarian cancer cells (HOCCs) clear. Here, we reveal a critical role for multifunctional protein p62/SQSTM1 (HOCCs). (sequestosome 1) plays important roles cell differentiation, proliferation as an antiapoptotic molecule. We found cisplatin-resistant SKOV3/DDP express...
This paper deals with the high accurate current set-points solution for interior permanent-magnet synchronous motors (IPMSM) in wide-speed range applications. Considering voltage and constraints, operating regions can be divided into maximum torque per ampere, current, field weakening, regions, which requires solving different nonlinear functions real time to obtain optimal set-points. Traditional methods including curve-fitting polynomial approximation (PA) are not easy these solutions,...
Diabetes mellitus is associated with cognitive dysfunction. Numerous previous studies have shown that type 1 diabetes-induced hyperglycaemia causes structural brain damage, such as a decrease in whole-brain grey matter. The impact of diabetes on the cerebral cortex poorly understood and requires further clarification. In present study, was induced via an intraperitoneal injection streptozotocin (50 mg/kg). Hematoxylin eosin (H&E) staining performed to detect morphological changes cortex,...
The electromagnetic suspension-type maglev train can reach ultrahigh-speed using long stator linear synchronous motors; however, slot effect makes the motors suffer from suspension force ripple, since it causes nonsinusoidal airgap magnetic field distribution. It has been expounded that electromagnet system is highly nonlinear and unstable in open loops. Additionally, trains experience disturbances uncertainties service. Therefore, robust disturbance-rejection control for necessary to...
This article proposes an adaptive model predictive current control (AM-MPCC) for surface-mounted permanent magnet linear synchronous motor systems to simultaneously enhance the robustness against flux, inductance, and resistance mismatches. First, conventional continuous set is analyzed, illustrating that parameter variations will inevitably deteriorate regulation performance. Then, model, which involves a disturbance term optimized change rate coefficient, proposed. The optimal coefficient...
The magnetic levitation technology has attracted blooming attention from all walks of life thanks to its superiorities such as noncontact and active control. While the intrinsic features open-loop instability strong nonlinearity, along with uncertain external disturbance make control particularly significant difficult. For speeding up convergence obtaining a better stability robustness, this article proposes an ultralocal model-free adaptive supertwisting nonsingular terminal sliding mode...
This paper presents an integrated ac choke that incorporates the common-mode (CM) suppression function into a three-phase differential-mode (DM) inductor. The proposed choke, together with other filter components, provides transformerless solution to issues caused by switching CM voltage in neutral-connected power converter systems. required high CM-to-DM inductance ratio is generated different magnetic paths novel structure. An approach based on circuit calculation can be applied...
CLIC4/mtCLIC, a chloride intracellular channel protein, localizes to mitochondria, endoplasmic reticulum (ER), nucleus and cytoplasm, participates in the apoptotic response stress. Apoptosis autophagy, main types of programmed cell death, seem interconnected under certain stress conditions. However, role CLIC4 autophagy regulation has yet be determined. In this study, we demonstrate upregulation nuclear translocation protein following starvation U251 cells. siRNA transfection enhanced with...
Cisplatin resistance is a difficult problem in clinical chemotherapy, and the mechanisms involved cisplatin require further study. In this study, we investigated role of chloride channel-3 (ClC-3) resistance. Autophagy was demonstrated by accumulation LC3-II, beclin 1 Atg12-Atg5. The ultrastructure changes were observed under electron microscope. Chemical staining with acridine orange or MDC used to detect acidic vesicular organelles. Quantification apoptosis detected PI Annexin V staining....
On control of the grid-connected inverter (GCI) with LCL filter, inverter-side current model predictive is adopted conventionally. The ultimate grid-side controlled indirectly by current. ideal scenario that directly controlled. However, conventional complicated and calculation heavy. This study proposed a novel direct (GSC-MPC) for GCI filter. Based on timing coordination both forward backward difference methods, connection established between output voltage. Meanwhile, proper mathematical...
This paper presents an efficiency optimization method for laser wireless power transmission (LWPT) system, focusing on the coordination and control of multiple diodes. A distributed (D-LWPT) system is proposed, which includes independent parallel chains. The has characteristics scalability, redundancy, flexibility. each key component in LWPT are discussed. Due to internal losses laser, also affected by power. For architecture, its flexibility allows rational allocation To achieve optimal...
Background Ischemic stroke (IS) is a major global cause of death and disability, linked to nucleotide metabolism imbalances. This study aimed identify metabolism-related genes associated with IS explore their roles in disease mechanisms for new diagnostic therapeutic strategies. Methods gene expression data were sourced from the GEO database. Differential analysis weighted co-expression network (WGCNA) conducted R, intersecting results genes. Functional enrichment connectivity map (cMAP)...