A5042745403- Insect symbiosis and bacterial influences
- Insect Resistance and Genetics
- Renal Diseases and Glomerulopathies
- Immune Cell Function and Interaction
- Insect-Plant Interactions and Control
- Probiotics and Fermented Foods
- Insect and Arachnid Ecology and Behavior
- Immune Response and Inflammation
- Viral Infectious Diseases and Gene Expression in Insects
- Gut microbiota and health
- Insect and Pesticide Research
- Microbial infections and disease research
- Diabetes and associated disorders
- Reproductive Biology and Fertility
- T-cell and B-cell Immunology
- Organ Transplantation Techniques and Outcomes
- Marine animal studies overview
- Plant Virus Research Studies
- Arctic and Antarctic ice dynamics
- Respiratory viral infections research
- Viral gastroenteritis research and epidemiology
- Influenza Virus Research Studies
- Bacteriophages and microbial interactions
- Antimicrobial Resistance in Staphylococcus
- Systemic Lupus Erythematosus Research
Showa University
2016-2024
Niigata University
2014-2021
Tokyo Medical University
2007-2016
Hiroshima University
2009-2016
Yamagata City Hospital Saiseikan
2016
Kobe University
2015
Tokai University
1996-2009
Nagoya University
2003-2009
Brigham and Women's Hospital
2006-2008
Harvard University
2006-2008
The accumulation of certain species bacteria in the intestine is involved both tissue homeostasis and immune-mediated pathologies. host mechanisms controlling intestinal colonization with commensal are poorly understood. We observed that under specific pathogen-free or germ-free conditions, intragastric administration Pseudomonas aeruginosa, E. coli, Staphylococcus aureus, Lactobacillus gasseri resulted increased small bacterial translocation mice lacking Cd1d, an MHC class I-like molecule,...
A pentanucleotide repetitive sequence, (TTAGG)n, has been isolated from a silkworm genomic library, using cross-hybridization with (TTNGGG)5 which is conserved among most eukaryotic telomeres. Both fluorescent in situ hybridization and Bal 31 exonuclease experiments revealed major clusters of (TTAGG)n at the telomeres all Bombyx chromosomes. To determine evolutionary origin this two types telomeric (TTAGG)5 hexanucleotide (TTAGGG)4, mainly vertebrate several invertebrate so far examined,...
When oral tolerance was induced in either specific pathogen-free (SPF) or germ-free (GF) mice, ovalbumin (OVA) feeding before immunization successfully SPF mice. On the other hand, OVA-specific immunoglobulin G1 (IgG1) and IgE titres OVA-fed GF mice were comparable to those phosphate-buffered saline-fed thus demonstrating that could not be The frequencies of CD25(+) CD4(+)/CD4(+) cells mesenteric lymph node (MLN) absolute number CD4(+) Peyer's patches MLN naive significantly lower than In an...
Anti-CD3 monoclonal antibody (mAb) has been shown to induce tolerance and be an effective treatment for diabetes both in animal models human trials. We have that anti-CD3 mAb given orally is biologically active the gut suppresses experimental autoimmune encephalitis by induction of a regulatory T-cell expresses latency-associated peptide (LAP) on its surface. In present study, we investigated effect oral prevention AKR mice which low-dose streptozocin (STZ) model induces autoimmunity β-cells...
Abstract Bacteroides , a predominant commensal bacteria in the gut, are thought to be responsible for development of inflammatory bowel disease (IBD). In present study, we examined whether or not bifidobacteria suppress B. vulgatus representative pathogenic species, both coculture system and gnotobiotic murine model. As result, Bifidobacterium infantis 1222 highly inhibited growth also significantly suppressed systemic antibody response raised by colonizing gut mice. Colonization mice...
The ability of Lactobacillus salivarius TI 2711 (LS 1) to displace periodontopathic bacteria, like Porphyromonas gingivalis and Prevotella intermedia, was studied using humanvolunteers. LS 1 one thousandfold more susceptible lactic acid than acidophilus, a representative acid-resistant strain frequently found at the sites caries, when these bacteria were exposed 50 mM acid. In an in vitro system, completely killed P. within 24 hours cultured together. clinical study, 57 subjects took tablets...
Two species of Lepidoptera, Ostrinia scapulalis and Ephestia kuehniella, harbour Wolbachia, which are maternally transmitted intracellular bacteria that often cause reproductive abnormalities in arthropods. While the infection O.scapulalis causes conversion genetic males into functional females (feminization), E. kuehniella induces cytoplasmic incompatibility. In present study, we investigated relative importance host Wolbachia factors differential expression alterations these insects. We...
An intracellular symbiont harbored by the aphid bacteriocyte, a specialized fat body cell, synthesizes in vivo substantially only one protein, symbionin, which is member of chaperonin-60 family molecular chaperones. Nucleotide sequence determination symbionin region endosymbiont genome revealed that it contains two-cistron operon sym. Just like Escherichia coli groE operon, sym was dually led heat shock and an ordinary promoter sequence. According to nucleotide sequence, 85.5% identical...
The aim of the study was to evaluate efficacy probiotics on gut-derived sepsis caused by Pseudomonas aeruginosa in immunocompromised mice.After oral inoculation P. aeruginosa, mice were treated with cyclophosphamide induce leucopenia and translocation intestinal into blood, thereby producing sepsis. In this model, administration 1 x 10(9) CFU Bifidobacterium longum strain BB536 for 10 days significantly (P < 0.01) increased survival rate compared groups administered either breve ATCC 15700...
The purpose of this study was to investigate the effects heat-killed Lactobacillus plantarum strain b240 (b240) on systemic infection by Salmonella enterica serovar Typhimurium (S. Typhimurium) and determine mechanism which protects against infection. Mice were administered either or saline orally for 3 weeks, then inoculated with S. Typhimurium. mice treated significantly protected as compared those fed saline. Moreover, translocation into each organ tested in that received tended be less...
Some strains of lactic acid bacteria are reported to inhibit the growth Helicobacter pylori and proposed be useful support so-called triple therapy for H. pylori. Although most must alive exert their anti-H. activity, some lactobacilli effective even when dead. One possible underlying mechanism such an activity non-living is reportedly co-aggregation with In this study, we found that a heat-killed form Lactobacillus johnsonii No.1088 (HK-LJ88) also other inhibited in vitro. Furthermore,...
MEPS Marine Ecology Progress Series Contact the journal Facebook Twitter RSS Mailing List Subscribe to our mailing list via Mailchimp HomeLatest VolumeAbout JournalEditorsTheme Sections 119:1-10 (1995) - doi:10.3354/meps119001 Breeding areas and southbound migrations of southern minke whales Balaenoptera acutorostrata Kasamatsu, F., Nishiwaki, S., Ishikawa, H. Southern are genetically separated from Northern Hemisphere whales. Seasonal take them tropical latitudes in winter high Antarctic...
ABSTRACT Human flora-associated (HFA) mice have been considered a tool for studying the ecology and metabolism of intestinal bacteria in humans, although they some limitations as model. Shifts dominant species microbiota HFA after administration human was revealed by 16S rRNA gene sequence terminal restriction fragment length polymorphism (T-RFLP) analyses. Characteristic fragments (T-RFs) were quantified proportion total peak area all T-RFs. Only T-RF at bp 366, identified...
Summary All phloem-feeding Homoptera possess symbiotic microorganisms. Although the phylogenetic position and anatomical location of micro- organisms differ, underlying theme symbiosis is same; microorganisms improve nutritional quality diet through provision essential amino acids. The has been well documented in aphids, but little information available from other homopteran groups. impact loss bacterial symbionts pea aphid Acyrthosiphon pisum Harris eukaryotic yeast-like Asian rice brown...