A5040149129- Effects and risks of endocrine disrupting chemicals
- Diet and metabolism studies
- Pesticide Exposure and Toxicity
- Toxic Organic Pollutants Impact
- Pesticide and Herbicide Environmental Studies
- Neuroscience and Neuropharmacology Research
- Weed Control and Herbicide Applications
- Per- and polyfluoroalkyl substances research
- Anesthesia and Neurotoxicity Research
- Pregnancy and Medication Impact
- Birth, Development, and Health
- Regulation of Appetite and Obesity
- Muscle Physiology and Disorders
- Radiopharmaceutical Chemistry and Applications
- Muscle metabolism and nutrition
- Pluripotent Stem Cells Research
- Biochemical effects in animals
- Pharmacological Effects and Toxicity Studies
- Drug-Induced Hepatotoxicity and Protection
- LGBTQ Health, Identity, and Policy
- Pesticide Residue Analysis and Safety
- Atmospheric chemistry and aerosols
- Agricultural safety and regulations
- Pharmaceutical and Antibiotic Environmental Impacts
- Air Quality and Health Impacts
Stantec (United States)
2023-2025
Cardno (United States)
2020-2021
University of Illinois Urbana-Champaign
2016-2020
Abbott Nutrition (United States)
2018
Abbott (United States)
2018
Society for Neuroscience
2018
The growth and organization of the developing brain are known to be influenced by hormones, but little is about whether disruption hormones affects cortical regions, such as mPFC. This region particularly important given its involvement in executive functions implication pathology many neuropsychiatric disorders. Here, we examine long-term effects perinatal exposure endocrine-disrupting compounds, phthalates, on mPFC associated behavior. investigation pertinent humans ubiquitously exposed...
Humans are ubiquitously exposed to many phthalates, a class of endocrine-disrupting chemicals commonly used in consumer goods, and diet, especially fatty food, is presumed be major source exposure. Here, we use rat model human prenatal exposure investigate the potential interactive effects an environmentally relevant mixture phthalates maternal high-fat diet (HFD). From gestation through postnatal day (P)10, dams consumed (0, 200, or 1000 μg/kg/d) were fed control HFD. In males, perinatal...
Cobalt (Co) alloys have been used for over seven decades in a wide range of medical devices, including, but not limited to, hip and knee implants, surgical tools, vascular stents, due to their favorable biocompatibility, durability, mechanical properties. A recent regulatory hazard classification review by the European Chemicals Agency (ECHA) resulted metallic Co as Class 1B Carcinogen (presumed carcinogenic potential humans), primarily based on inhalation rodent carcinogenicity studies with...
Consumers are confronted with conflicting information regarding the safety of specific foods. For example, Environmental Working Group (EWG) publishes an annual consumer guide in which they rank pesticide contamination 46 popular fruits and vegetables, includes designating 12 greatest as "Dirty Dozen," to help consumers reduce exposures toxic pesticides. However, guides like EWG's only incorporate some hazard assessment principles do not reflect a dietary risk assessment. Therefore, purpose...
Normal aging results in cognitive decline and nutritional interventions have been suggested as potential approaches for mitigating these deficits. Here, we used rats to investigate the effects of short- long-term dietary supplementation with leucine metabolite β-hydroxy-β-methyl butyrate (HMB) on working memory flexibility.Beginning ∼12 months age, male female Long-Evans were given twice daily access sipper tubes containing calcium HMB (450 mg/kg) or vehicle (285 mg/kg lactate) a sucrose...
Black Americans make up 13% of the U.S. population, yet account for 54% HIV deaths and 44% new diagnoses. Why do die from at such a disproportionate rate? In current study, we asked whether presence behavior in-group peers in public health settings may influence Americans' attention to information, given racialized nature HIV-stigma American communities. quasi-experimental field study conducted clinic (N = 260), found that patients were less likely pay HIV-prevention information other...
Perinatal exposure to endocrine disrupting chemicals negatively impacts health, but the mechanism by which such toxicants damage long-term reproductive and metabolic function is unknown. Lipid metabolism plays a pivotal role in steroid hormone synthesis as well energy utilization storage; thus, aberrant lipid regulation may contribute phthalate-driven health impairments. In order test this hypothesis, we specifically examined epigenetic disruptions pathways after perinatal phthalate...
The purpose of this study was to evaluate the individual contributions inhalation and dermal exposures urinary glyphosate levels following heavy residential consumer application a glyphosate-containing herbicide.A pilot conducted in which each participant mixed continuously spray-applied 16.3 gallons 0.96% solution for 100 min using backpack sprayer. Twelve participants were divided evenly into two exposure groups, one equipped assess other, exposure. Personal air samples (n = 12) patch 24)...
Due to the widespread application of glyphosate, a nonselective herbicide, variety resistant food crops, general population is exposed glyphosate through dietary intake. Despite this, exposures are considered low in comparison application-related exposures. Although previous studies have evaluated exposure horticultural and agricultural workers, date only one study, which we recently conducted, has characterized consumers following heavy residential glyphosate-containing herbicide yard...