A5036116999- Nanoparticles: synthesis and applications
- Computational Drug Discovery Methods
- Selenium in Biological Systems
- Laser-Ablation Synthesis of Nanoparticles
- Click Chemistry and Applications
- Advanced Nanomaterials in Catalysis
- Date Palm Research Studies
- Neurological Disorders and Treatments
- Synthesis and Reactivity of Sulfur-Containing Compounds
- Biochemical effects in animals
- Cholinesterase and Neurodegenerative Diseases
- Pain Management and Opioid Use
- Nanoparticle-Based Drug Delivery
- Cancer therapeutics and mechanisms
- Natural Antidiabetic Agents Studies
- Synthesis and biological activity
- Pain Mechanisms and Treatments
- Organophosphorus compounds synthesis
- Medicinal Plants and Neuroprotection
- Synthesis and Characterization of Heterocyclic Compounds
- Synthesis and Biological Evaluation
- Humic Substances and Bio-Organic Studies
- Free Radicals and Antioxidants
- Moringa oleifera research and applications
- Advanced Glycation End Products research
Kerman University of Medical Sciences
2014-2025
Islamic Azad University Kerman
2018
Stempeutics (India)
2015
Islamic Azad University of Najafabad
2014
To study the effects of an aqueous extract date fruit (Phoenix dactylifera L. Arecaceae) diet on diabetic polyneuropathy (DPN) in streptozotocin- (STZ-) induced rats.The a (DFE) neuropathy STZ-induced rats were evaluated and compared with nondiabetic control group, group (sham), vehicle respect to following parameters: open field behavioral test, motor nerve conduction velocity (MNCV), morphological observations.In model neuropathy, chronic treatment for 6 weeks DFE counteracted impairment...
Abstract: Quercetin (QE), a particular flavonoid, is well known for its medicinal effects, including anti-oxidant, hypoglycemic, and anti-inflammatory effects. In this review, the findings of QE effects on diabetes STZinduced, alloxan-induced, complications have been summarized with focus in vitro, vivo, clinical trials. Consequently, mediates several mechanisms, ameliorating tumor necrosis factor (TNF)-α, nuclear kappa-light-chain-enhancer activated B cells (NF-κB), interleukin (IL)-1β,...
Peripheral nerve tissue engineering is a field that uses cells, growth factors and biological scaffold material to provide nutritional physical support in the repair of injuries. The specific properties injectable human amniotic membrane-derived hydrogel including as well anti-inflammatory neuroprotective agents make it an ideal tool for repair, metformin may also aid regeneration. aim this study was investigate effects derived from membrane (AM) along with (MET) administration sciatic...
Background: Ischemic stroke can lead to cognitive impairment, and nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown slow down the progression of Alzheimer›s disease (AD). This study focused on rodent models investigate impact ischemic potential benefits aspirin in reducing impairment. Methods: The Morris water maze (MWM) was used evaluate memory learning seven groups (N=63) Wistar rats. Brain ischemia induced rat through temporary blocking both common carotid arteries permanent...
Diabetes mellitus is the most common metabolic disease with a high prevalence rate in human society that eventually leads to peripheral nervous system complications great number of patients. In present study, effects Angipars on nerve conduction velocity, histological alterations, and behavioral indices were investigated. was induced male rats by intraperitoneal injection streptozotocin (STZ). Six weeks after STZ injection, animals divided into five groups control, vehicle, 3 experimental...
This study was purposed to examine the cytotoxicity and functions of biologically synthesised bismuth nanoparticles (Bi NPs) produced by Delftia sp. SFG on human colon adenocarcinoma cell line HT-29. The structural properties Bi NPs were investigated using transmission electron microscopy, energy dispersive X-ray, X-ray diffraction techniques. cytotoxic effects analysed flow cytometry apoptosis while western blot analyses applied analyse cleaved caspase-3 expression. Oxidative stress (OS)...
Until now, the therapeutic potential of metal nanoparticles (NPs) has received much attention thanks to their unique properties. In addition, natural extracts plants have shown significant ability in various diseases. Therefore, present study aimed synthesize AuNPs using aqueous Hedra helix (Hh-AuNPs), Senna alexandrina (Sa-AuNPs), Thyme vulgaris (Tv-AuNPs) and Tribulus terrestris (Tt-AuNPs) then investigate antioxidant cytotoxic effects on cancerous normal breast cell lines. For this...
In the present study, Fe3 O4 magnetic nanoparticles were synthesized by coprecipitation of Fe(2+) and Fe(3+) ions used as a nanocarrier for production piroctone-olamine-loaded (Fe3 @PO NPs). The nanocrystalline structure prepared iron oxide species was confirmed X-ray diffraction spectroscopy method. Particle size distribution analysis showed that NPs in range 5-55 nm. magnetization curve (with saturation 28.2 emu/g) its ferromagnetic property. Loading PO on surface qualitatively verified...
The authors evaluated the cytotoxicity underlying mechanisms of biogenic tellurium (Te) nanorods (NRs) produced by Pseudomonas pseudoalcaligenes strain Te on PC12 cell line. half-maximal inhibitory concentration (IC50) value was estimated at 5.05 ± 0.07 ng/ml for NRs and 2.44 0.38 K2TeO3, respectively. viability inhibited dependent doses 1, 2.5, 5, 10, 20 ng/ml. principally induced late apoptosis or necrosis IC50 concentration, without effect caspase-3 activities. Furthermore, reduced...
Abstract Ferula species have been recognized as crucial medicinal plants that are known for producing a variety of sesquiterpenes, such sesquiterpene lactones and coumarins. However, guaianolide which contain an alpha‐methylene‐gamma‐lactone moiety, rare in spp. hindukushensis , endemic found Afghanistan, Pakistan, Iran, belongs to the genus. In this study, normal column chromatography technique was employed fractionate dichloromethane extract F. . The structures two sesquiterpenes were...
Background: Crataegus meyeri A. Pojark is one of Iran›s most well-known medicinal plants. This study aimed to assess the cytotoxic, antioxidant, and anti-inflammatory properties methanolic extract (MCM) leaves. Methods: MCM was prepared from dried First, cytotoxic impact determined via MTT test. Then, activity on lipopolysaccharide (LPS)-exposed J774A.1 cells examined by measuring NO production cyclooxygenase-2 (COX-2) gene expression using Griess test quantitative real-time polymerase chain...