A5016224466- Ichthyology and Marine Biology
- Turtle Biology and Conservation
- Marine and fisheries research
- Cancer Cells and Metastasis
- Fish Ecology and Management Studies
- MicroRNA in disease regulation
- Marine animal studies overview
- Cancer Genomics and Diagnostics
- Circular RNAs in diseases
- Linguistics and Discourse Analysis
- Migration, Aging, and Tourism Studies
- Amphibian and Reptile Biology
- Avian ecology and behavior
- Estrogen and related hormone effects
- Horticultural and Viticultural Research
- Numerical methods in inverse problems
- Diverticular Disease and Complications
- Coral and Marine Ecosystems Studies
- Anorectal Disease Treatments and Outcomes
- S100 Proteins and Annexins
- Historical Linguistics and Language Studies
- Marine Ecology and Invasive Species
- Appendicitis Diagnosis and Management
- Medical Imaging Techniques and Applications
- Chemical Safety and Risk Management
Université Paris Cité
2022-2025
Laboratoire de Linguistique Formelle
2022-2025
Georgetown University Medical Center
2019-2023
Georgetown University
2019-2023
Washington University in St. Louis
1978-2023
Linde (United States)
2022
International Union for Conservation of Nature (United States)
2022
University of Göttingen
2022
Georgetown Lombardi Comprehensive Cancer Center
2019
University of Miami
1995-2018
Genome-scale metabolic models are mathematically-structured knowledge bases that can be used to predict pathway usage and growth phenotypes. Furthermore, they generate test hypotheses when integrated with experimental data. To maximize the value of these models, centralized repositories high-quality must established, adhere established standards model components linked relevant databases. Tools for visualization further enhance their utility. meet needs, we present BiGG Models...
The transition from Pleistocene to Archaic/Mesolithic is analyzed in broad ecological terms. trend throughout most of the toward increasing technological diversity linked expectable tendency increase resource reliability. advent culture enabled man reliability by diversifying his base. Resources were largely K-selected type, economical procure with simple technology but generally subject overexploitation. By end diversification base had reached a maximum number areas, and increased could...
Large oceanic migrants play important roles in ecosystems, yet many species are of conservation concern as a result anthropogenic threats, which incidental capture by fisheries is frequently identified. The last large populations the leatherback turtle, Dermochelys coriacea, occur Atlantic Ocean, but interactions with industrial could jeopardize recent positive population trends, making bycatch mitigation priority. Here, we perform first pan-Atlantic analysis spatio-temporal distribution...
Cancer stem cells (CSC) appear to have increased metastatic potential, but mechanisms underlying this are poorly defined. Here we show that VEGFA induction of Sox2 promotes EMT and tumor metastasis. In breast lines primary cancer culture, rapidly upregulates SOX2 expression, leading SNAI2 induction, EMT, invasion We downregulates miR-452, which acts as a novel metastasis suppressor directly target the 3'-untranslated region (3'-UTR). stimulates Sox2- Slug-dependent cell invasion. increases...
Triple-negative breast cancer (TNBC) is a highly aggressive and metastatic subtype, which generally untreatable once it metastasizes. We hypothesized that interfering with the Receptor for Advanced Glycation End-products (RAGE) signaling small molecule RAGE inhibitors (TTP488/Azeliragon FPS-ZM1) would impair TNBC metastasis fundamental mechanisms underlying tumor progression metastasis. Both TTP488 FPS-ZM1 impaired spontaneous experimental of models, reducing to greater degree than FPS-ZM1....
Multiple juxtacrine and paracrine interactions occur between cancer cells non-cancer of the tumor microenvironment (TME) that direct progression. Cancer Associated Fibroblasts (CAFs) are an integral component TME, majority breast stroma is comprised CAFs. Heterotypic TME via soluble agents, including cytokines, hormones, growth factors, secreted microRNAs. We previously identified a microRNA signature indicative hyperactive MAPK signaling (hMAPK-miRNA signature) significantly associated with...
Background Sea turtles are long-distance migrants with considerable behavioural plasticity in terms of migratory patterns, habitat use and foraging sites within among populations. However, for the most widely migrating turtle, leatherback turtle Dermochelys coriacea, studies combining data from individuals different populations uncommon. Such however critical to better understand intra- inter-population variability take it into account implementation conservation strategies this critically...
Marine animals, such as turtles, seabirds and pelagic fishes, are observed to travel congregate around eddies in the open ocean. Mesoscale eddies, large swirling ocean vortices with radius scales of approximately 50-100 km, provide environmental variability that can structure these populations. In this study, we investigate use mesoscale by 24 individual juvenile loggerhead sea turtles (Caretta caretta) Brazil-Malvinas Confluence region. The influence on is assessed collocating turtle...
Circle hooks have been promoted as an alternative to traditional J-hooks in pelagic longline fisheries minimize bycatch mortality and injury sea turtles other marine wildlife. We evaluated the effect of hook type (circle vs J-hook) on catch length composition target non-target species Uruguayan fishery, for both American- Spanish-style longlines. The sample unit used comparing catches was two consecutive sections longline, each with a different type. For American-style 39,822 were deployed...
MEPS Marine Ecology Progress Series Contact the journal Facebook (Twitter) RSS Mailing List Subscribe to our mailing list via Mailchimp HomeLatest VolumeAbout JournalEditorsTheme Sections 479:235-250 (2013) - DOI: https://doi.org/10.3354/meps10222 High-use areas, seasonal movements and dive patterns of juvenile loggerhead sea turtles in Southwestern Atlantic Ocean Caren Barceló1,3,5,*, Andrés Domingo2, Philip Miller3, Leonardo Ortega2, Bruno Giffoni4, Gilberto Sales4, Lianne McNaughton5,...
The population abundance estimates used in stock assessments or required to establish management measures, depend on the sampling of entire demographic spectrum a resident given area. However, for sea turtles, most are based mainly nesting beach survey data and only consider fraction population. Southwest Atlantic Ocean (SWA) is an important foraging development area juveniles loggerhead turtle Caretta caretta where reproductive stocks from various beaches mix. Declines C. populations have...