A5082472729- Extracellular vesicles in disease
- Ferroptosis and cancer prognosis
- Renal cell carcinoma treatment
- MicroRNA in disease regulation
- Viral Infections and Vectors
- Vector-Borne Animal Diseases
- Cancer Immunotherapy and Biomarkers
- Viral gastroenteritis research and epidemiology
- interferon and immune responses
- Viral Infections and Outbreaks Research
- Economic and Technological Developments in Russia
- PI3K/AKT/mTOR signaling in cancer
- Regional Socio-Economic Development Trends
- BRCA gene mutations in cancer
- Hedgehog Signaling Pathway Studies
- Immunotherapy and Immune Responses
- Cancer-related molecular mechanisms research
- Epigenetics and DNA Methylation
- Fire effects on ecosystems
- Cancer Diagnosis and Treatment
- Bladder and Urothelial Cancer Treatments
Bashkir State Medical University
2023-2024
Ministry of Health of the Russian Federation
2024
Ufa Institute of Chemistry
2021-2024
Institute of Biochemistry and Genetics of Ufa Scientific Centre
2022
Bashkir State University
2022
Russian Academy of Sciences
2022
The Russian Presidential Academy of National Economy and Public Administration
2014
Immunotherapy with immune checkpoint inhibitors (ICIs) has shown high efficiency in clear cell renal carcinoma (ccRCC) treatment. However, the response to therapy among patients varies greatly. Modern studies demonstrate potential of exosomal miRNAs as diagnostic and prognostic markers oncopathology. This study aimed evaluate miRNA expression profiles miRNAs-144, -146a, -149, -126, -155 treated inhibitors. The included 35 whose venous blood samples were taken before after ICI therapy....
Hemorrhagic fever with renal syndrome (HFRS), caused by Orthohantaviruses, occupies one of the leading places among natural focal human diseases, for which there are no modern accurate and highly sensitive diagnostic methods. To improve this situation, a better understanding Hantavirus pathogenesis HFRS is required. Determination expression level exosomal microRNAs (miRNAs) in serum/plasma patients makes them potential biomarkers diagnosing predicting HFRS. The purpose study was to analyze...
Применение ингибиторов контрольных точек иммунитета (ИКТИ) является перспективной терапией в лечении онкологических заболеваний, частности почечно-клеточной карциномы (ПКК). Несмотря на революционный прорыв рака данной группой препаратов, существенная доля пациентов не демонстрирует ответа лечение. На сегодняшний день оценка уровня экспрессии белка PD-L1 (лиганда рецептора запрограммированной клеточной гибели 1) опухолевых клетках единственным одобренным методом определения показаний к...
Background: Hemorrhagic fever with renal syndrome (HFRS), caused by orthohantaviruses, occupies one of the leading places among natural focal human diseases, for which there are no modern accurate and highly sensitive diagnostic methods. To improve this situation, a better understanding hantavirus pathogenesis HFRS is required. The expression levels circulating microRNAs in serum or plasma patients during infection make them potential therapeutic biomarkers diagnosis HFRS. aim study: analyze...
Russian Abstract: Работа предлагает теоретический взгляд на региональную экономическую политику в России, показывает влияние разных формаций и экономических школ процесс развития региональной пространственной экономики, рассматривает проблему управления территориальным развитием современном этапе (Федеральные округа: методы механизмы реализации федеральной политики региональном уровне), исследованы стратегические приоритеты макрорегионов России.
Despite significant advance in clear cell renal carcinoma treatment, immune checkpoint inhibitors (ICIs) still have limited therapeutic efficacy. Taking into account the resistance to immunotherapy, observed malignant neoplasms, search for predictive markers of response ICI therapy patients with (ccRCC) is under active investigation. Recent scientific studies demonstrate that exosomal miRNAs are key modulators tumor signaling and determinants microenvironment. Dysregulation can affect...
Introduction: Hemorrhagic fever with renal syndrome (HFRS), caused by Orthohantaviruses, occupies one of the leading places among natural focal human diseases, for which there are no modern accurate and highly sensitive diagnostic methods. To improve this situation, a better understanding Hantavirus pathogenesis HFRS is required. Determination expression level exosomal microRNAs (miRNAs) in serum/plasma patients makes them potential biomarkers diagnosing predicting HFRS. The purpose study...