Purpose: To assess feasibility and preliminary efficacy of a mobile/online-based (mHealth) mindfulness intervention for cancer patients their caregivers to reduce distress improve quality life (QoL). Material Methods: Two-arm randomized controlled trial within Kaiser Permanente Northern California targeting who received chemotherapy informal caregivers. The group commercially available program 8 weeks. wait-list control usual care. We assessed using retention adherence rates obtained...

Abstract Objective Assess the feasibility of conducting a cluster randomized controlled trial (RCT) comparing technology‐delivered mindfulness‐based intervention (MBI) programs against waitlist control arm targeting advanced cancer patients and their informal caregivers. Methods Two‐arm RCT within Kaiser Permanente Northern California. We recruited with metastatic solid malignancies or hematological cancers Intervention‐group participants chose to use either commercially available...

Approximately 20% of women suffer from postpartum depression (PPD). Due to barriers such as limited access care, half the with PPD do not receive treatment. Therefore, it is critical identify effective and scalable interventions. Traditional mindfulness programs have been in reducing depressive symptoms, however remains a barrier. A self-paced mobile health (mHealth) program may fit lifestyle busy mothers who are unable attend in-person classes. However, little known regarding feasibility or...

Understanding how structural racism is associated with adolescent mental health critical to advance equity.

Introduction: Wearable technologies can enhance measurements completed from home by participants in decentralized clinical trials. These have shown promise monitoring patient wellness outside the setting. However, there are challenges handling data and its interpretation when using consumer wearables, requiring input statisticians scientists. This article describes three methods to estimate daily steps address gaps Apple Watch cancer patients uses one of these an analysis association between...

This cross-sectional study compares the prevalence and risk for diagnosed undiagnosed prenatal depression among pregnant individuals of different races ethnicities.

Early puberty is associated with higher risk of adverse health and behavioral outcomes throughout adolescence adulthood. US girls are experiencing earlier substantial racial/ethnic differences. We examined the association between breastfeeding pubertal timing to identify modifiable factors early potential sources differences in development. A prospective cohort study 3331 racially/ethnically diverse born at Kaiser Permanente Northern California (KPNC) 2004 06. All data were obtained from...

Abstract Earlier puberty has been associated with numerous adverse mental, emotional, and physical health outcomes. Obesity is a known risk factor for earlier in girls, but research boys yielded inconsistent findings. We examined sex- race/ethnicity-specific associations between childhood obesity multiethnic cohort of 129,824 adolescents born at Kaiser Permanente Northern California medical facility 2003 2011. used Weibull regression models to explore breast development onset (thelarche)...

Earlier puberty is associated with adverse health outcomes, such as mental issues in adolescence and cardiometabolic diseases adulthood. Despite rapid growth of the Asian American, Native Hawaiian, Pacific Islander populations US, limited research exists on their pubertal timing, potentially masking disparities.

Informal caregivers are a critical source of support for cancer patients. However, their perspectives not routinely collected, despite health impacts related to the burden caregiving. We created TOGETHERCare smartphone application (app) collect observer-reported outcomes regarding patient's and caregiver's perceptions own mental physical health, provide tips resources self-care patient care. enrolled 54 between October 2020 March 2021 from Kaiser Permanente Northern California (KPNC), an...

By eliminating the requirement for participants to make frequent visits research sites, mobile phone applications ("apps") may help decentralize clinical trials. Apps also be an effective mechanism capturing patient-reported outcomes and other endpoints, helping optimize patient care during outside of

Early puberty is associated with adverse health outcomes, but little known regarding early-life determinants influencing pubertal timing. We examined the associations between maternal gestational weight gain (GWG) and timing of onset breast development (thelarche) pubic hair (pubarche) in a cohort 2,070 girls born Kaiser Permanente Northern California facility 2005 2006. Using Weibull regression models accommodating interval censoring adjusting for important confounders, we found that excess...

Abstract Background Girls who experience early-life familial stress may have heightened risk of early puberty, which has adverse implications for adolescent and adult health. We assessed the association between household intactness pubertal onset using a racially/ethnically diverse cohort girls from Northern California. Methods A prospective study 26,044 born in 2003-10. living with both parents birth up to 6 years were considered come “intact” households while others constituted...

Early puberty increases risk of adverse health conditions throughout the life course. US girls are experiencing earlier without clear reasons. Studies suggest early factors, such as infant growth, may influence pubertal timing. We assessed associations between growth and onset breast development (thelarche), pubic hair (pubarche), menarche in girls.

Abstract Mobile phone applications (“apps”) are potentially an effective, low-burden method to collect patient-reported outcomes outside the clinical setting. Using such apps consistently and in a timely way is critical for complete accurate data capture, but no studies of concurrent reporting by cancer patient–caregiver dyads have been published peer-reviewed literature. This study assessed app engagement, defined as adherence, timing, attrition with two smartphone applications, one adult...

Purpose: Children of mothers with prenatal depression have elevated risk for later in life. Pregnant women are hesitant to use antidepressants due fear adverse fetal effects. To inform prevention, this study examined associations between maternal and antidepressant use, adolescent depressive symptoms suicidality. Patients Methods: Prospective data from 74,695 mother-adolescent dyads the Kaiser Permanente Northern California integrated healthcare delivery system were used. Three exposure...

Background Timely collection of patient-reported outcomes (PROs) decreases emergency department visits and hospitalizations increases survival. However, little is known about the outcome predictivity unpaid informal caregivers’ reporting using similar clinical assessments. Objective The aim this study to assess whether caregivers adults with cancer adhered a planned schedule for electronically collecting if PROs were associated future events. Methods We developed 2 iPhone apps collect PROs,...

Objectives: Racial/ethnic minority women have disproportionately lower breast cancer survival rates compared to white women. As minorities in the US are exposed higher levels of discrimination, and exposure discrimination has been associated with shorter telomere lengths (TLs), we investigated association between perceived everyday TL a multiethnic sample survivors.Design: We examined cohort 58 survivors who participated pilot study investigate biological stress. Participants were drawn from...

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Following publication of the original article [1], authors reported that Table 4 was incorrectly presented. The revised and corrected version is shown below.