A5047557865- Gestational Diabetes Research and Management
- Birth, Development, and Health
- Pregnancy and preeclampsia studies
- Obesity, Physical Activity, Diet
- Bariatric Surgery and Outcomes
- Diabetes Management and Education
- Metabolism, Diabetes, and Cancer
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Treatment and Management
- Diabetes Management and Research
- Obesity and Health Practices
- Effects and risks of endocrine disrupting chemicals
- Per- and polyfluoroalkyl substances research
- Maternal Mental Health During Pregnancy and Postpartum
- Child Nutrition and Water Access
- COVID-19 and Mental Health
- Air Quality and Health Impacts
- Food Security and Health in Diverse Populations
- Health disparities and outcomes
- COVID-19 Impact on Reproduction
- Cancer, Lipids, and Metabolism
- Cancer Risks and Factors
- Breastfeeding Practices and Influences
- Chronic Disease Management Strategies
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
Kaiser Permanente
2016-2025
Community Link
2024
Cohort (United Kingdom)
2024
Oakland University
2003-2023
University of California, Davis
2021
University of Naples Federico II
1991-2020
Hyattsville Community Development Corporation
2019
Seattle University
2019
Camden and Campbelltown Hospitals
2018
MedStar Health
2018
African Americans are disproportionately affected by type 2 diabetes (T2DM) yet few studies have examined T2DM using genome-wide association approaches in this ethnicity. The aim of study was to identify genes associated with the American population. We performed a Genome Wide Association Study (GWAS) Affymetrix 6.0 array 965 African-American cases and end-stage renal disease (T2DM-ESRD) 1029 population-based controls. most significant SNPs (n = 550 independent loci) were genotyped...
Recent data show that gestational diabetes mellitus (GDM) prevalence has increased by ∼10–100% in several race/ethnicity groups during the past 20 years. A true increase of GDM, aside from its adverse consequences for infants newborn period, might also reflect or contribute to current patterns increasing and obesity, especially offspring. Therefore, public health aspects GDM need more attention. The frequency usually reflects type 2 underlying population (1,2). Established risk factors are...
Background —Glycemic control is associated with microvascular events, but its effect on the risk of heart failure not well understood. We examined association between hemoglobin (Hb) A Ic and hospitalization and/or death in a population-based sample adult patients diabetes assessed whether this differed by patient sex, pathogenesis, hypertension status. Methods Results —A cohort design was used baseline January 1, 1995, June 30, 1996, follow-up through December 31, 1997 (median 2.2 years)....
OBJECTIVE Some preclinical in vivo studies and limited human data suggest a possible increased risk of bladder cancer with pioglitazone therapy. This is an interim report ongoing cohort study examining the association between therapy patients diabetes. RESEARCH DESIGN AND METHODS includes 193,099 Kaiser Permanente Northern California diabetes registry who were ≥40 years age 1997 2002. Those prior excluded. Ever use each medication (defined as two or more prescriptions within 6 months) was...
In Brief OBJECTIVE: To estimate the relationship between rate of gestational weight gain before 50-g, 1-hour oral glucose challenge test screening for diabetes mellitus (GDM) and subsequent risk GDM. METHODS: We conducted a nested case–control study (345 women with GDM 800 in control group) within multiethnic cohort delivering 1996 1998 who were screened at 24–28 weeks gestation. was diagnosed according to National Diabetes Data Group plasma cut-offs 100-g, 3-hour tolerance test. Women's...
OBJECTIVE: Self-monitoring of blood glucose (SMBG) is a cornerstone diabetes care, but little known about barriers to this self-care practice. RESEARCH DESIGN AND METHODS: This cross-sectional study examines SMBG practice patterns and in 44,181 adults with pharmacologically treated from the Kaiser Permanente Northern California Region who responded health survey (83% response rate). The primary outcome self-reported frequency SMBG. RESULTS: Although most patients reported some level...
In Brief OBJECTIVE: Women with gestational diabetes mellitus (GDM) and their offspring are at increased risk of developing diabetes. Although increases in prevalence have been reported the United States, it is unknown whether this trend also occurring for GDM. We examined trends yearly cumulative incidence GDM between years 1991 2000. METHODS: A cohort study 267,051 pregnancies screened that occurred among members Northern California Kaiser Permanente Medical Care Program, representing 86.8%...
OBJECTIVE There are limited data on the risk of pulmonary disease in patients with diabetes. The aim this study was to evaluate and compare incidence asthma, chronic obstructive (COPD), fibrosis, pneumonia, lung cancer without a diagnosis RESEARCH DESIGN AND METHODS We conducted retrospective, longitudinal cohort using electronic records large health plan northern California. Age sex were available for all members (n = 1,811,228). Data confounders subcohort that responded surveys 121,886),...
<h3>Importance</h3> Studies suggest pioglitazone use may increase risk of cancers. <h3>Objective</h3> To examine whether for diabetes is associated with bladder and 10 additional <h3>Design, Setting, Participants</h3> Cohort nested case-control analyses among persons diabetes. A cancer cohort followed 193 099 aged 40 years or older in 1997-2002 until December 2012; 464 case patients matched controls were surveyed about confounders. analysis cancers included 236 507 1997-2005 June 2012....
To examine whether the association between gestational diabetes mellitus (GDM) and BMI category varies by racial/ethnic group.In a cohort of 123,040 women without recognized pregravid who delivered babies 1995 2006 at Kaiser Permanente Northern California, we examined disparities in prevalence GDM population-attributable risk (PAR) associated with overweight/obesity.Among all groups, age-adjusted increased increasing (kg/m(2)) category. However, Asian Filipina had 9.9 8.5%, respectively,...
Abstract The Environmental Influences on Child Health Outcomes (ECHO)-Wide Cohort Study (EWC), a collaborative research design comprising 69 cohorts in 31 consortia, was funded by the National Institutes of (NIH) 2016 to improve children’s health United States. EWC harmonizes extant data and collects new using standardized protocol, ECHO-Wide Data Collection Protocol (EWCP). EWCP visits occur at least once per life stage, but frequency timing vary across cohorts. As March 4, 2022,...
Importance The COVID-19 pandemic led to widespread lockdowns and school closures that may have affected screen time among children. Although restrictions were strongest early in the pandemic, it is unclear how changed as progressed. Objective To evaluate change children’s from before during July 2019 through August 2021. Design, Setting, Participants This a longitudinal cohort study with repeated measures of collected 2 periods. Children aged 4 12 years their parent enrolled 3 pediatric...
Background: Per- and polyfluoroalkyl substances (PFAS) are persistent ubiquitous chemicals associated with risk of adverse birth outcomes. Results previous studies have been inconsistent. Associations between PFAS outcomes may be affected by psychosocial stress. Objectives: We estimated in relation to prenatal concentrations evaluate whether maternal stress modifies those relationships. Methods: included 3,339 participants from 11 prospective cohorts the Environmental influences on Child...
BackgroundChildhood maltreatment is associated with adverse health outcomes and this risk can be transmitted to the next generation. We aimed investigate association between exposure maternal childhood common physical mental problems, neurodevelopmental disorders, related comorbidity patterns in offspring.Methods.We conducted a retrospective cohort study using data from Environmental influences on Child Health Outcomes (ECHO) Program, which was launched influence of early life exposures...
Importance Food insecurity is a growing public health concern, but its association with perinatal complications remains unclear. Objective To examine whether food in pregnancy was associated the risk of and determine these potential associations differed by receipt assistance. Design, Setting, Participants This cohort study used data from survey conducted between June 22, 2020, September 9, 2022, at Kaiser Permanente Northern California, an integrated care system serving diverse population...
OBJECTIVE To determine whether diabetes defined by isolated postchallenge hyperglycemia (IPH) (2-h plasma glucose ≥ 11.1 mmol/l with fasting [FPG] &lt; 7.0 mmol/l) increases the risk of fatal cardiovascular disease (CVD) in older women and men. RESEARCH DESIGN AND METHODS In a prospective study, we followed 769 men 1,089 women, aged 50–89 years, who had no history or myocardial infarction demonstrated (i.e., FPG when they underwent oral tolerance testing at baseline 1984–1987. RESULTS At...
When patients miss scheduled medical appointments, continuity and effectiveness of healthcare delivery is reduced, appropriate monitoring health status lapses, the cost services increases. We evaluated relationship between missed appointments glycemic control (glycosylated hemoglobin or HbA1c) in a large, managed care population diabetic patients.Missed appointment rate was related cross-sectionally to among 84,040 members Kaiser Permanente Northern California Diabetes Registry during 2000....
The purpose of the present study was to effects age, weight change, and covariates on lipid lipoprotein levels cross-sectionally prospectively in an elderly population.A community-based sample 1041 men 1303 women aged 50 93 years studied 1984 1987, with follow-up 372 545 8 later. In cross-sectional study, total cholesterol (TC) LDL (LDL-C) decreased HDL (HDLC) increased age (all P < .001) but not women. prospective TC, LDL-C, HDL-C all both women, groups (50 64 years, 65 74 > or = 75 years)...
OBJECTIVE—To examine risk perception for diabetes among women with histories of gestational mellitus (GDM). RESEARCH DESIGN AND METHODS—We surveyed 217 GDM who were enrolled in a managed-care plan and did not currently have diabetes. In cross-sectional design, we assessed the associations between perceptions current lifestyle behavioral practices, plans to modify behaviors, recent behavior changes. Multivariable models included participant characteristics as well potential modifiers...
To pilot, among women with gestational diabetes mellitus (GDM), the feasibility of a prenatal/postpartum intervention to modify diet and physical activity similar Diabetes Prevention Program. The was delivered by telephone, support for breastfeeding addressed.The goal help return their prepregnancy weight, if it normal, or achieve 5% reduction from weight overweight. Eligible participants were identified shortly after GDM diagnosis; 83.8% consented be randomly assigned usual medical care (96...
Hedderson MM, Darbinian JA, Ferrara A. Disparities in the risk of gestational diabetes by race-ethnicity and country birth. Paediatric Perinatal Epidemiology 2010. Little information exists on association between maternal birth (GDM). We examined within each group whether GDM differs women born inside outside US. The study was a cohort 216 089 who delivered an infant 1995 2004 with plasma glucose data from screening 50-g challenge test diagnostic 100-g, 3-h oral tolerance test. age-adjusted...
OBJECTIVE—In 2000, the American Diabetes Association proposed adoption of Carpenter and Coustan criteria for diagnosis gestational diabetes mellitus (GDM). The cutoffs are lower than previously recommended National Data Group (NDDG) values would result in higher prevalence GDM. Our aim is to estimate magnitude change GDM using thresholds as compared with NDDG by age ethnicity. RESEARCH DESIGN AND METHODS—Cross-sectional study 28,330 women aged 14–49 years who gave birth 1996 were members...
OBJECTIVE—The purpose of this study was to examine trends in postpartum glucose screening for women with gestational diabetes mellitus (GDM), predictors screening, impaired fasting (IFG) and diabetes, pre-diabetes detected by plasma (FPG) versus a 75-g oral tolerance test (OGTT). RESEARCH DESIGN AND METHODS—This cohort 14,448 GDM pregnancies delivered between 1995 2006. Postpartum defined as performance either an FPG or OGTT at least 6 weeks after delivery within 1 year delivery....