A5068428626- Air Quality and Health Impacts
- Heavy Metal Exposure and Toxicity
- Birth, Development, and Health
- Climate Change and Health Impacts
- Arsenic contamination and mitigation
- Gestational Diabetes Research and Management
- Pregnancy and Medication Impact
- Energy and Environment Impacts
- Obesity, Physical Activity, Diet
- Noise Effects and Management
- Maternal Mental Health During Pregnancy and Postpartum
- Child Nutrition and Water Access
- Mercury impact and mitigation studies
- Environmental Justice and Health Disparities
- Nutritional Studies and Diet
- Pregnancy and preeclampsia studies
- Fluoride Effects and Removal
- Epigenetics and DNA Methylation
- Polyomavirus and related diseases
- Health, Environment, Cognitive Aging
- Health disparities and outcomes
- Effects and risks of endocrine disrupting chemicals
- Per- and polyfluoroalkyl substances research
- Food Security and Health in Diverse Populations
- Toxic Organic Pollutants Impact
Hofstra University
2025
Cohen Children's Medical Center
2025
Northwell Health
2025
University of Southern California
2016-2025
Southern California University for Professional Studies
2019-2024
Cohort (United Kingdom)
2024
Keck Hospital of USC
2023-2024
California State University, Northridge
2023
Outcomes Research Consortium
2023
Brigham and Women's Hospital
2023
The intestinal microbiome plays a critical role in infant development, and delivery mode feeding method (breast milk vs formula) are determinants of its composition. However, the importance beyond first days life is unknown, studies associations between composition have been generally limited to comparisons exclusively breastfed formula-fed infants, with little consideration given combination both breast formula.To examine at approximately 6 weeks life.Prospective observational study 102...
Abstract The Environmental Influences on Child Health Outcomes (ECHO)-Wide Cohort Study (EWC), a collaborative research design comprising 69 cohorts in 31 consortia, was funded by the National Institutes of (NIH) 2016 to improve children’s health United States. EWC harmonizes extant data and collects new using standardized protocol, ECHO-Wide Data Collection Protocol (EWCP). EWCP visits occur at least once per life stage, but frequency timing vary across cohorts. As March 4, 2022,...
Prenatal chemical exposures can influence maternal and child health; however, few industrial chemicals are routinely biomonitored. We assessed an extensive panel of contemporary emerging in 171 pregnant women across the United States (U.S.) Puerto Rico Environmental influences on Child Health Outcomes (ECHO) Program. simultaneously measured urinary concentrations 89 analytes (103 total representing 73 parent compounds) nine groups: bactericides, benzophenones, bisphenols, fungicides...
Polyomaviruses (PyV) are potentially tumorigenic in humans. However, limited data exist on the population seroprevalence of PyVs and individual characteristics that relate to seropositivity. Using multiplex serology, we determined 10 human (BK, JC, KI, WU, MCV, HPyV6, HPyV7, TSV, HPyV9, HPyV10) among controls from a population-based skin cancer case-control study (n = 460) conducted New Hampshire between 1993 1995. On subset participants 194), methylation at CpG dinucleotides across genome...
Arsenic has been linked to disrupted immune function and greater infection susceptibility in highly exposed populations. Well arsenic levels above the U.S. EPA limit occur our study area are of particular concern for pregnant women infants.We investigated whether utero exposure affects risk infections respiratory symptoms over first year life.We prospectively obtained information on infant symptoms, including their duration treatment (n = 412) at 4, 8, 12 months using a parental telephone...
Importance Preeclampsia, gestational hypertension, and diabetes, the most common pregnancy complications, are associated with substantial morbidity mortality in mothers children. Little is known about biological processes that link occurrence of these complications adverse child outcomes; altered aging growing fetus up to birth one molecular pathway increasing interest. Objective To evaluate whether exposure each 3 (gestational preeclampsia) accelerated or decelerated age children at birth....
Recent studies in Canadian and Mexican populations suggest an association of higher prenatal fluoride exposure with poorer neurobehavioral development, but whether this holds for US-based is unknown.
Background: Previous studies indicate that concentrations of arsenic in breast milk are relatively low even areas with high drinking-water arsenic. However, it is uncertain whether breastfeeding leads to reduced infant exposure regions lower concentrations.Objective: We estimated the relative contributions and formula during early infancy a U.S. population.Methods: measured home tap water (n = 874), urine from 6-week-old infants 72), mothers 9) enrolled New Hampshire Birth Cohort Study...
Gestational diabetes mellitus (GDM) is a major pregnancy complication with detrimental effects for both mothers and their children. Accumulating evidence has suggested potential role arsenic (As) exposure in the development of GDM, but current studies have not assessed As from water, urine or toenail samples. We investigated association between risk glucose intolerance GDM among 1151 women enrolled New Hampshire Birth Cohort Study. Arsenic was measured home well water via biomarkers (i.e.,...
The burden of childhood and adult obesity disproportionally affects Hispanic African-American populations in the US, these groups as well with lower income education levels are disproportionately affected by environmental pollution. Pregnancy is a critical developmental period where maternal exposures may have significant impacts on infant growth future health mother. We initiated "Maternal And Developmental Risks from Environmental Social Stressors (MADRES)" cohort study to address gaps...
Background: Reduced fetal growth increases the risk for adverse health outcomes. Growing evidence suggests that metal exposures contribute to reduced growth, but little is known about effects of complex mixtures. Objectives: We investigated impact a mixture metals on birth weight gestational age (BW GA) in Maternal and Developmental Risks from Environmental Social Stressors study, predominately lower-income Hispanic pregnancy cohort Los Angeles, California. Methods: Cadmium (Cd), cobalt...
<h3>Importance</h3> The balance of mercury risk and nutritional benefit from fish intake during pregnancy for the metabolic health offspring to date is unknown. <h3>Objective</h3> To assess associations exposure with syndrome in children alterations biomarkers inflammation children. <h3>Design, Setting, Participants</h3> This population-based prospective birth cohort study used data studies performed 5 European countries (France, Greece, Norway, Spain, UK) between April 1, 2003, February 26,...
Abstract Background Child blood pressure (BP) is predictive of future cardiovascular risk. Prenatal exposure to metals has been associated with higher BP in childhood, but most studies have evaluated elements individually and measured at a single time point. We investigated impacts prenatal metal mixture exposures on longitudinal changes during childhood elevated 11 years age. Methods The current study included 176 mother-child pairs from the Rhea Study Heraklion, Greece focused eight...
A growing number of studies have identified both toxic and essential metals which influence fetal growth. However, most conducted single-cohort analyses, are often limited by narrow exposure ranges, evaluated individually. The objective the current study was to conduct an environmental mixture analysis metal impacts on growth, pooling data from three geographically demographically diverse cohorts in United States participating Environmental Influences Child Health Outcomes program. pooled...
Importance Fetal growth is precisely programmed and could be interrupted by environmental exposures during specific times pregnancy. Insights on potential sensitive windows of air pollution exposure in association with birth weight are needed. Objective To examine the ambient heterogeneity individual- neighborhood-level stressors. Design, Setting, Participants Data a cohort low-income Hispanic women singleton term pregnancy were collected from 2015 to 2021 ongoing Maternal Developmental...
Abstract Background Epigenetic clocks are promising tools for assessing biological age. We assessed the accuracy of pediatric epigenetic in gestational and chronological age determination. Results Our study used data from seven tissue types on three DNA methylation profiling microarrays found that Knight Bohlin performed similarly blood cells, while Lee clock was superior placental samples. The pediatric-buccal-epigenetic best buccal samples, Horvath is recommended children's cell NeoAge...
Precision Health aims to revolutionize disease prevention by leveraging information across multiple omic datasets (multi-omics). However, existing methods generally do not consider personalized environmental risk factors (e.g., pollutants).