Tina V. Hartert
A5029533781- Respiratory viral infections research
- Asthma and respiratory diseases
- Neonatal Respiratory Health Research
- Pediatric health and respiratory diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Congenital Diaphragmatic Hernia Studies
- Tracheal and airway disorders
- Respiratory and Cough-Related Research
- Pneumonia and Respiratory Infections
- Respiratory Support and Mechanisms
- Air Quality and Health Impacts
- Inhalation and Respiratory Drug Delivery
- Viral gastroenteritis research and epidemiology
- Obesity, Physical Activity, Diet
- IL-33, ST2, and ILC Pathways
- Child and Adolescent Health
- Delphi Technique in Research
- Noise Effects and Management
- Birth, Development, and Health
- Influenza Virus Research Studies
- Pregnancy and Medication Impact
- Maternal Mental Health During Pregnancy and Postpartum
- Health, Environment, Cognitive Aging
- Animal Virus Infections Studies
- Climate Change and Health Impacts
Vanderbilt University Medical Center
2016-2025
Vanderbilt University
2015-2024
Northern Arizona University
2024
Johns Hopkins University
1996-2024
Pennsylvania State University
2024
RTI International
2024
Cohort (United Kingdom)
2024
Vanderbilt Health
2015-2024
Monroe Carell Jr. Children's Hospital
2022
University of Colorado Anschutz Medical Campus
2022
We conducted a nested case–control study to examine the association between asthma and invasive pneumococcal disease. The population included persons 2 49 years of age who were enrolled in Tennessee's Medicaid program (TennCare) for more than one year during period (1995 through 2002) resided counties participating prospective laboratory-based surveillance For each subject with disease, 10 age-matched controls without disease randomly selected from same population. TennCare files queried...
We used a deeply sequenced dataset of 910 individuals, all African descent, to construct set DNA sequences that is present in these individuals but missing from the reference human genome. aligned 1.19 trillion reads genome (GRCh38), collected failed align, and assembled into contiguous (contigs). then compared contigs one another identify unique representing regions pan-genome Our analysis revealed 296,485,284 bp 125,715 distinct populations demonstrating contains ~10% more than current...
Bronchiolitis during infancy is associated with an increased risk of childhood asthma. Whether winter viral infections cause asthma or are a manifestation predisposition to development unknown.To study the relationship virus infection and asthma.We studied over 95,000 infants born between 1995 2000 followed through 2005 who were enrolled in Tennessee Medicaid program from birth early determine whether infant peak alters developing asthma.Among 95,310 children five seasons childhood, tracked...
Respiratory syncytial virus (RSV) is a major health care burden with particularly high worldwide morbidity and mortality rate among infants. Data suggest that severe RSV-associated illness in part caused by immunopathology associated robust type 2 response.
Abstract The Environmental Influences on Child Health Outcomes (ECHO)-Wide Cohort Study (EWC), a collaborative research design comprising 69 cohorts in 31 consortia, was funded by the National Institutes of (NIH) 2016 to improve children’s health United States. EWC harmonizes extant data and collects new using standardized protocol, ECHO-Wide Data Collection Protocol (EWCP). EWCP visits occur at least once per life stage, but frequency timing vary across cohorts. As March 4, 2022,...
Importance Cefepime and piperacillin-tazobactam are commonly administered to hospitalized adults for empirical treatment of infection. Although has been hypothesized cause acute kidney injury cefepime neurological dysfunction, their comparative safety not evaluated in a randomized clinical trial. Objective To determine whether the choice between affects risks or dysfunction. Design, Setting, Participants The Antibiotic Choice on Renal Outcomes (ACORN) trial compared vs whom clinician...
Importance Exposure to outdoor air pollution contributes childhood asthma development, but many studies lack the geographic, racial and ethnic, socioeconomic diversity evaluate susceptibility by individual-level community-level contextual factors. Objective To examine early life exposure fine particulate matter (PM 2.5 ) nitrogen oxide (NO 2 risk middle childhood, whether individual characteristics modify associations between asthma. Design, Setting, Participants This cohort study included...
To compare the efficacy and safety of inpatient oral antibiotic treatment (oral) versus standard parenteral (intravenous) for right-sided staphylococcal endocarditis in injection drug users.In a prospective, randomized, non-blinded trial, febrile users were assigned to begin or intravenous (IV) on admission, before blood culture results available. Oral therapy consisted ciprofloxacin rifampin. Parenteral was oxacillin vancomycin, plus gentamicin first 5 days. Antibiotic dosing adjusted renal...
Rhinoviruses frequently cause the common cold but have not been considered important causes of acute respiratory hospitalizations in children.A population-based surveillance study was performed among children <5 years age who were hospitalized with symptoms or fever and resided within counties encompassing Nashville, Tennessee, Rochester, New York, from October 2000 through September 2001. Data collected included questionnaires, nasal throat swabs for viral culture polymerase chain reaction...
Prospective data on viral etiology and clinical characteristics of bronchiolitis upper respiratory illness (URI) in infants are limited.This prospective cohort enrolled previously healthy term during inpatient or outpatient visits for acute URI September to May 2004 2008. Illness severity was determined using an ordinal score. Common viruses were identified by real-time reverse-transcriptase polymerase chain reaction.Of 648 infants, 67% 33% visits. Seventy percent had bronchiolitis, 3% croup...
We determined the prevalence of human metapneumovirus (hMPV) infection in adults with asthma who were prospectively enrolled after hospitalization for an acute exacerbation. Nasal wash specimens collected at admission and 3 months discharge tested hMPV by real-time reverse-transcription polymerase chain reaction assays. was detected 7 (6.9%) 101 subjects 1 (1.3%) 75 follow-up (odds ratio, [95% confidence interval, 0.9-312]; P=.03). None patients positive follow-up, strongly suggesting that...
Abstract The African Diaspora in the Western Hemisphere represents one of largest forced migrations history and had a profound impact on genetic diversity modern populations. To date, fine-scale population structure descendants remains largely uncharacterized. Here we present variation from deeply sequenced genomes 642 individuals North South American, Caribbean West populations, substantially increasing lexicon human genomic suggesting much to be discovered African-admixed populations...