Brant Imhoff

ORCID: 0009-0006-7257-5673
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About
Contact & Profiles
Research Areas
  • Airway Management and Intubation Techniques
  • Cardiac Arrest and Resuscitation
  • Respiratory Support and Mechanisms
  • Tracheal and airway disorders
  • Intensive Care Unit Cognitive Disorders
  • Foreign Body Medical Cases
  • Anesthesia and Sedative Agents
  • Potassium and Related Disorders
  • Heart Failure Treatment and Management
  • Cardiac, Anesthesia and Surgical Outcomes
  • Electrolyte and hormonal disorders
  • Sepsis Diagnosis and Treatment
  • Trauma Management and Diagnosis
  • Antibiotics Pharmacokinetics and Efficacy

Vanderbilt University Medical Center
2022-2025

Wake Forest University
2024

Cancer Research And Biostatistics
2023

Whether video laryngoscopy as compared with direct increases the likelihood of successful tracheal intubation on first attempt among critically ill adults is uncertain. Download a PDF Research Summary. In multicenter, randomized trial conducted at 17 emergency departments and intensive care units (ICUs), we randomly assigned undergoing to video-laryngoscope group or direct-laryngoscope group. The primary outcome was attempt. secondary occurrence severe complications during intubation; were...

10.1056/nejmoa2301601 article EN New England Journal of Medicine 2023-06-16

Importance Cefepime and piperacillin-tazobactam are commonly administered to hospitalized adults for empirical treatment of infection. Although has been hypothesized cause acute kidney injury cefepime neurological dysfunction, their comparative safety not evaluated in a randomized clinical trial. Objective To determine whether the choice between affects risks or dysfunction. Design, Setting, Participants The Antibiotic Choice on Renal Outcomes (ACORN) trial compared vs whom clinician...

10.1001/jama.2023.20583 article EN JAMA 2023-10-14

ABSTRACT Background Emergency tracheal intubation is a common and high-risk procedure. Ketamine etomidate are sedative medicines commonly used to induce anesthesia for emergency intubation, but whether the induction medication affects patient outcomes uncertain. Research Question Does use of ketamine decrease incidence death among adults undergoing compared etomidate? Study Design Methods The Randomized trial Sedative choice Intubation (RSI) pragmatic, multicenter, unblinded, parallel-group,...

10.1101/2025.01.18.25320768 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2025-01-18

Among critically ill patients undergoing orotracheal intubation in the emergency department (ED) or intensive care unit (ICU), failure to visualise vocal cords and intubate trachea on first attempt is associated with an increased risk of complications. Two types laryngoscopes are commonly available: direct video laryngoscopes. For adults tracheal intubation, it remains uncertain whether use a laryngoscope increases incidence successful compared laryngoscope.The DirEct versus VIdeo...

10.1136/bmjopen-2022-068978 article EN cc-by-nc BMJ Open 2023-01-01

Hypoxemia is a common and life-threatening complication during emergency tracheal intubation of critically ill adults. The administration supplemental oxygen prior to the procedure ("preoxygenation") decreases risk hypoxemia intubation.Whether preoxygenation with noninvasive ventilation prevents adults, compared mask, remains uncertain.The PRagmatic trial Examining OXygenation Intubation (PREOXI) prospective, multicenter, non-blinded randomized comparative effectiveness being conducted in 7...

10.1101/2023.03.23.23287539 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2023-03-24

Abstract Introduction Among critically ill patients undergoing orotracheal intubation in the emergency department (ED) or intensive care unit (ICU), failure to visualize vocal cords and intubate trachea on first attempt is associated with an increased risk of complications. Two types laryngoscopes are commonly available: direct video laryngoscopes. For adults tracheal intubation, it remains uncertain whether use a laryngoscope increases incidence successful compared laryngoscope. Methods...

10.1101/2022.11.07.22282046 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2022-11-08
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