Cori Withers
- Airway Management and Intubation Techniques
- Cardiac Arrest and Resuscitation
- Respiratory Support and Mechanisms
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Influenza Virus Research Studies
- COVID-19 epidemiological studies
- Cardiac, Anesthesia and Surgical Outcomes
- Venous Thromboembolism Diagnosis and Management
- Heparin-Induced Thrombocytopenia and Thrombosis
- Infectious Encephalopathies and Encephalitis
- Respiratory viral infections research
- Anesthesia and Sedative Agents
- Intensive Care Unit Cognitive Disorders
- Viral gastroenteritis research and epidemiology
- Vaccine Coverage and Hesitancy
University of Colorado System
2025
Wake Forest University
2024
University of Colorado Denver
2023
Among critically ill adults undergoing tracheal intubation, hypoxemia increases the risk of cardiac arrest and death. The effect preoxygenation with noninvasive ventilation, as compared an oxygen mask, on incidence during intubation is uncertain.
For critically ill adults undergoing emergency tracheal intubation, failure to intubate the trachea on first attempt occurs in up 20% of cases and is associated with severe hypoxemia cardiac arrest. Whether using a tube introducer ("bougie") increases likelihood successful intubation compared an endotracheal stylet remains uncertain.To determine effect use bougie vs attempt.The Bougie or Stylet Patients Undergoing Intubation Emergently (BOUGIE) trial was multicenter, randomized clinical...
Abstract Introduction Understanding the changing epidemiology of adults hospitalized with coronavirus disease 2019 (COVID-19) informs research priorities and public health policies. Methods Among (≥18 years) laboratory-confirmed, acute COVID-19 between 11 March 2021, 31 August 2022 at 21 hospitals in 18 states, those during severe respiratory syndrome 2 (SARS-CoV-2) Omicron-predominant period (BA.1, BA.2, BA.4/BA.5) were compared to from earlier Alpha- Delta-predominant periods. Demographic...
ABSTRACT Background Emergency tracheal intubation is a common and high-risk procedure. Ketamine etomidate are sedative medicines commonly used to induce anesthesia for emergency intubation, but whether the induction medication affects patient outcomes uncertain. Research Question Does use of ketamine decrease incidence death among adults undergoing compared etomidate? Study Design Methods The Randomized trial Sedative choice Intubation (RSI) pragmatic, multicenter, unblinded, parallel-group,...
Hypoxemia is a common and life-threatening complication during emergency tracheal intubation of critically ill adults. The administration supplemental oxygen prior to the procedure ("preoxygenation") decreases risk hypoxemia intubation.Whether preoxygenation with noninvasive ventilation prevents adults, compared mask, remains uncertain.The PRagmatic trial Examining OXygenation Intubation (PREOXI) prospective, multicenter, non-blinded randomized comparative effectiveness being conducted in 7...