A5042607878- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Maternal and fetal healthcare
- Neonatal Respiratory Health Research
- Maternal and Perinatal Health Interventions
- Preterm Birth and Chorioamnionitis
- Prenatal Screening and Diagnostics
- Assisted Reproductive Technology and Twin Pregnancy
- Infant Development and Preterm Care
- Platelet Disorders and Treatments
- Child Nutrition and Feeding Issues
- Inflammatory Biomarkers in Disease Prognosis
- Cardiovascular Issues in Pregnancy
- Hemoglobinopathies and Related Disorders
- Breastfeeding Practices and Influences
- Complement system in diseases
- Cardiovascular Disease and Adiposity
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Global Maternal and Child Health
- Gestational Diabetes Research and Management
- Blood Coagulation and Thrombosis Mechanisms
- Dysphagia Assessment and Management
- Clinical Nutrition and Gastroenterology
- Venous Thromboembolism Diagnosis and Management
- Nitric Oxide and Endothelin Effects
St. Vincent's Birmingham
2025
Medical College of Wisconsin
2015-2024
The University of Melbourne
2024
Leeds and York Partnership NHS Foundation Trust
2016-2021
John Hunter Hospital
2019
University of Oklahoma Health Sciences Center
2012-2018
Society for Maternal-Fetal Medicine
2016
Oklahoma City University
2014
University of Oklahoma
2014
Royal Hospital for Women
2014
Platelet counts of less than 150,000 per cubic millimeter during uncomplicated pregnancies are described as gestational thrombocytopenia if no alternative cause is identified. may be even lower in women with pregnancy-related complications. However, the occurrence and severity throughout pregnancy not defined.
When a pregnant or postpartum woman presents with sudden and severe microangiopathic hemolytic anemia (MAHA) thrombocytopenia, three syndromes that require urgent care must be considered: (1) preeclampsia features/hemolysis, elevated liver function tests, low platelets (PE/HELLP) syndrome; (2) thrombotic thrombocytopenic purpura (TTP); (3) complement-mediated microangiopathy (C-TMA; also referred to as atypical hemolytic-uremic syndrome). The distinction among these is often unclear because...
The novel coronavirus disease 2019 (COVID-19) pandemic is causing a necessary, rapid adjustment within the field of obstetrics. Corticosteroid use mainstay therapy for those women delivering prematurely. Unfortunately, corticosteroid has been associated with worse outcomes in COVID-19 positive patients. Given this information, it necessary that obstetricians adjust practice to carefully weigh fetal benefits maternal risks. Therefore, our institution examined risks and altered...
The novel coronavirus disease 2019 (COVID-19) is spreading fast and affecting the clinical workers at much higher risk than general population. Little known about COVID-19 effect on pregnant women; however, emerging evidence suggests they may be high of asymptomatic disease. In light projected shortage personal protective equipment (PPE), there an aggressive attempt conservation. obstetrics, guidelines PPE use are controversial differ among hospitals, globally, as well nationally. centers...
ABSTRACT Background Emergency tracheal intubation is a common and high-risk procedure. Ketamine etomidate are sedative medicines commonly used to induce anesthesia for emergency intubation, but whether the induction medication affects patient outcomes uncertain. Research Question Does use of ketamine decrease incidence death among adults undergoing compared etomidate? Study Design Methods The Randomized trial Sedative choice Intubation (RSI) pragmatic, multicenter, unblinded, parallel-group,...
Preterm birth is a leading cause of infant mortality and child morbidity. not always unexpected, yet standard prenatal care does offer anticipatory education to parents at risk delivering preterm, which leaves unprepared make health choices during the pregnancy that can improve survival decrease morbidity in case preterm birth.To evaluate effect Preemie Prep for Parents (P3) program on maternal knowledge birth, preparation decision-making, anxiety.Recruitment this randomized clinical trial...
Multiple myeloma is typically a disease found in older women and rare diagnosis pregnancy.A 22-year-old woman, gravida 1 para 0, at 32 3/7 weeks of gestation presented with nausea, vomiting, rib back pain. She was hypertensive, anemic, thrombocytopenic, acute renal insufficiency, hypercalcemia laboratory parameters indicative pancreatitis. admitted to the obstetric intensive care unit working diagnoses preeclampsia, pancreatitis, nephrolithiasis, insufficiency. ultimately delivered because...
Hematologists are often needed to assist with the management of microangiopathic emergencies in pregnancy. A firm understanding diagnosis and preeclampsia severe features, hemolysis elevated liver enzyme low platelet syndrome, disseminated intravascular coagulation, which most common causes emergencies, is critical. However, being able consider when other (acute fatty pregnancy, congenital acquired thrombotic thrombocytopenic purpura, complement mediated microangiopathy, antiphospholipid...
To determine the prevalence of Vitamin D (VitD) deficiency/insufficiency in mothers preterm neonates less than or equal to 32 weeks gestation and if current level VitD supplementation used for is appropriate.Prospective study from 10th May 2015 1st November 2016.Neonatal Intensive Care Unit at Canberra Hospital.Mothers their born gestation.Maternal levels were obtained within 3-4 days following delivery. Neonatal first life, age, 6-8 age. Demographic data on intake parenteral nutrition,...
Abstract Background Cardiovascular disease (CVD) is the leading cause of death in women every major developed country and most emerging nations. Complications pregnancy, including preeclampsia, indicate a subsequent increase cardiovascular risk. There may be primary care provider knowledge gap regarding preeclampsia as risk factor for CVD. The objective our study to determine how often internists at an academic institution inquire about history compared smoking, hypertension diabetes, when...
Abstract Background Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is caused by antibodies against human platelet antigens (HPA). However, in many cases that meet clinical criteria for the condition, maternal sera do not have HPA antibodies. In studies examining whether leukocyte antigen (HLA) cause FNAIT, results are limited inconclusive. This study sought to examine clinically suspected FNAIT with absent had different HLA antibody strength specificity compared controls. Study...
Syncytiotrophoblast stress is theorized to drive development of preeclampsia, but its molecular causes and consequences remain largely undefined. Multiple hormones implicated in preeclampsia signal via the Gαq cascade, leading hypothesis that excess signaling within syncytiotrophoblast may contribute. First, we present data supporting increased antioxidant responses villous samples human preeclamptic placenta. Second, was activated mouse placenta using Cre-lox DREADD methodologies....