Christine W. Hockett
- Birth, Development, and Health
- Obesity, Physical Activity, Diet
- Gestational Diabetes Research and Management
- Maternal Mental Health During Pregnancy and Postpartum
- Food Security and Health in Diverse Populations
- Breastfeeding Practices and Influences
- Pregnancy and preeclampsia studies
- COVID-19 and Mental Health
- Diabetes Management and Research
- Child Nutrition and Water Access
- Nutritional Studies and Diet
- Diabetes and associated disorders
- Obesity and Health Practices
- Prenatal Substance Exposure Effects
- COVID-19 Impact on Reproduction
- Folate and B Vitamins Research
- Family Support in Illness
- Fatty Acid Research and Health
- Health disparities and outcomes
- Early Childhood Education and Development
- Neuroscience of respiration and sleep
- Child Abuse and Trauma
- Mobile Health and mHealth Applications
- Diabetes Treatment and Management
- HIV-related health complications and treatments
Avera Health
2022-2025
University of South Dakota
2021-2025
Avera McKennan Hospital & University Health Center
2024
University of Colorado Denver
2015-2024
University of Sioux Falls
2022-2024
Cohort (United Kingdom)
2024
University of Michigan–Ann Arbor
2024
University of Colorado Anschutz Medical Campus
2020
Colorado School of Public Health
2013-2020
The Medical Center of Aurora
2018
Importance The COVID-19 pandemic led to widespread lockdowns and school closures that may have affected screen time among children. Although restrictions were strongest early in the pandemic, it is unclear how changed as progressed. Objective To evaluate change children’s from before during July 2019 through August 2021. Design, Setting, Participants This a longitudinal cohort study with repeated measures of collected 2 periods. Children aged 4 12 years their parent enrolled 3 pediatric...
Experts hypothesized increased weight gain in children associated with the coronavirus disease 2019 (COVID-19) pandemic. Our objective was to evaluate whether rate of change child body mass index (BMI) during COVID-19 pandemic compared prepandemic years. The study population 1996 ages 2 19 years at least 1 BMI measure before and drawn from 38 pediatric cohorts across United States participating Environmental Influences on Child Health Outcomes-wide cohort study. We modeled using linear mixed...
Earlier pubertal onset may be associated with an increased risk of chronic diseases. However, the extent to which growth in first 5 years life-an important developmental life stage that lays foundation for later health outcomes-is remains understudied.
Abstract Background Sex differences in body composition are appreciated throughout the lifespan with probable contributions from sex steroids: testosterone and estrogen. The purpose of this longitudinal observational study was to determine if emerge during first months life healthy infants, corresponding age at which male infants produce endogenous testosterone. Methods Linear growth parameters using air displacement plethysmography were obtained 602 after birth again 5 age. Rate change...
Importance The prevalence of obesity among youths 2 to 19 years age in the US from 2017 2018 was 19.3%; previous studies suggested that school lunch consumption associated with increased obesity. Healthy, Hunger-Free Kids Act 2010 (HHFKA) strengthened nutritional standards school-based meals. Objective To evaluate association between HHFKA and youth body mass index (BMI). Design, Setting, Participants This cohort study conducted using data Environmental Influences on Child Health Outcomes...
Importance Limited access to healthy foods, resulting from residence in neighborhoods with low food access, is a public health concern. The contribution of this exposure early life child obesity remains uncertain. Objective To examine associations neighborhood during pregnancy or childhood body mass index (BMI) and risk. Design, Setting, Participants Data cohorts participating the US nationwide Environmental Influences on Child Health Outcomes consortium between January 1, 1994, March 31,...
Importance Prenatal alcohol exposure (PAE) and prenatal tobacco (PTE) are risk factors associated with adverse neurobehavioral cognitive outcomes. Objective To quantify long-term associations of PAE PTE brain activity in early middle childhood via electroencephalography (EEG). Design, Setting, Participants This cohort study included participants enrolled the Safe Passage Study (August 2007 to January 2015), from which a subset 649 were followed up Environmental Influences on Child Health...
Prenatal fish intake is a key source of omega-3 (ω-3) polyunsaturated fatty acids needed for brain development, yet generally low, and studies addressing associations with autism spectrum disorder (ASD) related traits are lacking. This study aimed to examine prenatal ω-3 supplement use both diagnosis broader autism-related traits. Participants were drawn from 32 cohorts in the Environmental influences on Child Health Outcomes Cohort Consortium. Children born between 1999 2019 part ongoing...
Abstract Background Research suggests racial/ethnic disparities in prenatal exposure to endocrine disrupting environmental phenols (EPs) limited populations. However, no studies have investigated EP across the U.S. Objectives To estimate demographic differences urinary EPs among participants Environmental influences on Child Health Outcomes (ECHO) Cohort. Methods An analysis of 4006 pregnant ECHO was performed, with 7854 specimens collected from 1999–2020. Racial/ethnic identity...
Abstract Aims To examine the associations of intrauterine exposure to maternal diabetes and obesity with offspring insulin resistance, β‐cell function oral disposition index in a longitudinal observational study ethnically diverse offspring. Methods A total 445 who were exposed ( n =81) or not =364) utero completed two fasting blood measurements at mean sd ) ages 10.5 (1.5) 16.5 (1.2) years, respectively, an glucose tolerance test second visit. We used linear mixed models general univariate...
There is significant global variation in the prevalence of diabetic ketoacidosis (DKA) at diagnosis among youth with type 1 diabetes (T1D). However, data for 2 (T2D) are limited, even developed countries. We compared DKA individuals T1D and T2D from SEARCH Diabetes Youth (SEARCH) Registry Onset India (YDR) registries.
Understanding the landscape-level determinants of West Nile virus (WNV) can aid in mapping high-risk areas and enhance disease control prevention efforts. This study analyzed spatial patterns human WNV cases three South Dakota during 2003-2007 investigated influences land cover, hydrology, soils, irrigation, elevation by using case-control models. Land all influenced risk, although main drivers were different each area. Risk for was generally higher with rural cover than developed areas,...
OBJECTIVES Breastfeeding practices may protect against offspring obesity, but this relationship is understudied among women with obesity. We describe the associations between breastfeeding and child BMI for age z-score (BMIz), stratified by maternal BMI. METHODS analyzed 8134 dyads from 21 cohorts in Environmental Influences on Child Health Outcomes Program. Dyads data pre-pregnancy BMI, infant feeding practices, ≥1 assessment ages of 2 6 years were included. The continuous BMIz assessed...
Abstract Using pooled vaginal microbiota data from pregnancy cohorts (N = 683 participants) in the Environmental influences on Child Health Outcomes (ECHO) Program, we analyzed 16S rRNA gene amplicon sequences to identify clinical and demographic host factors that associate with structure both within across diverse cohorts. PERMANOVA models, assessed associated community pregnancy, examined whether were conserved populations, tested independent combined effects of state types (CSTs) using...
Summary Background American Indian (AI) youth are at high risk for type 2 diabetes. Objectives To partner with Eastern Band of Cherokee Indians and Navajo Nation to develop a culturally sensitive behavioural intervention (Tribal Turning Point; TTP) assess feasibility in an 8‐month randomized pilot study. Methods We enrolled 62 overweight/obese AI children (7–10 years) who participated ≥1 parent/primary caregiver. Intervention participants ( n = 29) attended 12 group classes five individual...
Abstract Background Prior research has demonstrated bidirectional associations between gestational diabetes mellitus (GDM) and perinatal maternal depression. However, the association GDM, prenatal depression, postpartum depression (PPD) not been examined in a prospective cohort longitudinally. Methods Participants current analysis included 5,822 women from National Institutes of Health’s Environmental influences on Child Health Outcomes (ECHO) Research Program: N = 4,606 with Neither GDM nor...
Summary Objective To examine associations of maternal gestational diabetes mellitus (GDM) with offspring cardiovascular biomarkers from late childhood through adolescence. Methods We used mixed effects linear regression models to GDM (n = 92 cases 597) average levels serum lipids (total cholesterol, high‐density lipoprotein [HDL], low‐density [LDL], and triglycerides) systolic blood pressure (SBP) across two research visits spanning approximately 10.6 16.9 years age. In sex‐stratified...
This longitudinal study compared children’s health behaviors before the COVID-19 pandemic versus during pandemic. analysis examined association between individual-level characteristics and behavior change. Four prospective cohort studies in Environmental influences on Child Health Outcomes (ECHO) Program contributed data. Children aged 4–12 years their caregivers were recruited California, Colorado, North Dakota, New Hampshire. Dietary intake, physical activity, screen time, sleep duration...
Longitudinal measures of diet spanning pregnancy through adolescence are needed from a large, diverse sample to advance research on the effect early-life nutrition child health. The Environmental influences Child Health Outcomes (ECHO) Program, which includes 69 cohorts,>33,000 pregnancies, and >31,000 children in its first seven-year cycle, provides such data, now publicly available. To describe dietary intake data available ECHO Program as August 31, 2022 (end year 6 Cycle 1) adolescence,...
-3 fatty acid consumption during pregnancy is recommended for optimal outcomes and offspring health. We examined characteristics associated with self-reported fish or