A5036408222- Birth, Development, and Health
- Gestational Diabetes Research and Management
- Obesity, Physical Activity, Diet
- Statistical Methods and Bayesian Inference
- Statistical Methods in Clinical Trials
- Nutritional Studies and Diet
- Health, Environment, Cognitive Aging
- Statistical Methods and Inference
- Asthma and respiratory diseases
- Pregnancy and preeclampsia studies
- Food Allergy and Anaphylaxis Research
- Breastfeeding Practices and Influences
- Air Quality and Health Impacts
- Per- and polyfluoroalkyl substances research
- Bayesian Methods and Mixture Models
- Advanced Causal Inference Techniques
- Eosinophilic Esophagitis
- Urban Agriculture and Sustainability
- Statistical Distribution Estimation and Applications
- Allergic Rhinitis and Sensitization
- Hormonal and reproductive studies
- Adipose Tissue and Metabolism
- Optimal Experimental Design Methods
- Consumer Attitudes and Food Labeling
- Child Nutrition and Water Access
University of Colorado Denver
2014-2024
University of Colorado Anschutz Medical Campus
2014-2024
Children's Hospital Colorado
2021-2024
Colorado School of Public Health
2014-2023
University of Colorado System
2020-2022
The Medical Center of Aurora
2018-2021
ENT and Allergy
2020
Denver School of Nursing
2019
RELX Group (Netherlands)
2017
Society of Nuclear Medicine and Molecular Imaging
2015
GLIMMPSE is a free, web-based software tool that calculates power and sample size for the general linear multivariate model with Gaussian errors (http://glimmpse.SampleSizeShop.org/). provides user-friendly interface computation of size. We consider models fixed predictors, predictors single covariate. Validation experiments demonstrate matches accuracy previously published results, performs well against simulations. provide several online tutorials based on research in head neck cancer. The...
Importance The COVID-19 pandemic led to widespread lockdowns and school closures that may have affected screen time among children. Although restrictions were strongest early in the pandemic, it is unclear how changed as progressed. Objective To evaluate change children’s from before during July 2019 through August 2021. Design, Setting, Participants This a longitudinal cohort study with repeated measures of collected 2 periods. Children aged 4 12 years their parent enrolled 3 pediatric...
Given that gene duplication is a major driving force of evolutionary change and the key mechanism underlying emergence new genes biological processes, this study sought to use novel genome-wide approach identify have undergone lineage-specific duplications or contractions among several hominoid lineages. Interspecies cDNA array-based comparative genomic hybridization was used individually compare copy number variation for 39,711 cDNAs, representing 29,619 human genes, across five species,...
We followed up swimming performance times of 321 women and 319 men who participated in the US Masters Swimming Championships over a 12-yr period. All swimmers placed top 10 their age group 3 yr (mean = 5 yr). A random coefficients model for repeated measures was used to derive line best fit from regression lines each subject. Both 50- 1,500-m declined modestly until approximately 70 age, where more rapid decline observed both women. Compared with swimming, 50-m freestyle slowly age. The rate...
To use human cartilage samples and a mouse model of osteoarthritis (OA) to determine whether extracellular superoxide dismutase (EC-SOD) is constituent evaluate there relationship between EC-SOD deficiency OA.Samples were obtained from femoral heads at the time joint replacement surgery for OA or neck fracture. Samples tibial STR/ort mice CBA control compared 5, 15, 35 weeks age. was measured by enzyme-linked immunosorbent assay, Western blotting, immunohistochemistry techniques. Real-time...
To examine associations between pregnancy physical activity and neonatal fat mass fat-free mass, birth weight, small for gestational age (SGA).We analyzed 826 mother-neonate pairs (term births) participating in the longitudinal Healthy Start study. The Pregnancy Physical Activity Questionnaire was used to assess total energy expenditure meeting American College of Obstetricians Gynecologists (College) guidelines during early pregnancy, midpregnancy, late pregnancy. Models were adjusted...
The impact of specific maternal fuels and metabolic measures during early late gestation on neonatal body composition is not well defined.To determine how circulating glucose, lipids, insulin resistance in the first second halves pregnancy influence composition.A prospective pre-birth cohort enrolling pregnant women, Healthy Start Study, was conducted, which fasting serum samples were collected twice to measure insulin, hemoglobin A1c, triglyceride, total cholesterol, high-density...
To explore the longitudinal association of neonatal adiposity (fat mass percentage) with BMI trajectories and childhood overweight obesity from ages 2 to 6 years.
Resting and exercise fuel metabolism was assessed in three different phases of the menstrual cycle, characterized by levels estrogen relative to progesterone: early follicular (EF, low progesterone), midfollicular (MF, elevated estrogen, midluteal (ML, progesterone). It hypothesized that glucose utilization whole body carbohydrate oxidation would decrease sequentially from EF MF ML phase. Normal-weight healthy females, experiencing a regular were recruited. Subjects moderately active but not...
Abstract Background Sex differences in body composition are appreciated throughout the lifespan with probable contributions from sex steroids: testosterone and estrogen. The purpose of this longitudinal observational study was to determine if emerge during first months life healthy infants, corresponding age at which male infants produce endogenous testosterone. Methods Linear growth parameters using air displacement plethysmography were obtained 602 after birth again 5 age. Rate change...
Objective To examine the relationships between protease inhibitor (PI) therapy, body fat distribution and metabolic disturbances in HIV lipodystrophy syndrome. Design Cross-sectional study. Setting primary care practices. Patients PI-treated patients with (n = 14) 13) PI-naive 5) without lipodystrophy. Main outcome measures Body composition was assessed by physical examination, dual-energy X-ray absorptiometry computed tomography. Insulin sensitivity (SI) measured using insulin-modified...
Abstract Aims To examine the associations of intrauterine exposure to maternal diabetes and obesity with offspring insulin resistance, β‐cell function oral disposition index in a longitudinal observational study ethnically diverse offspring. Methods A total 445 who were exposed ( n =81) or not =364) utero completed two fasting blood measurements at mean sd ) ages 10.5 (1.5) 16.5 (1.2) years, respectively, an glucose tolerance test second visit. We used linear mixed models general univariate...
Studying the developmental precursors of allergy may help explain mechanisms (or etiology) allergic disease. We studied childhood respiratory and diseases in a pre-birth cohort from United States.We assessed associations between maternal history asthma development offspring. also with rhinitis.Maternal rhinitis was self-reported during early pregnancy. Offspring information obtained electronic medical records. Adjusted Cox proportional hazard models offspring up to 8 years. A similar...