A5035614018- Cancer survivorship and care
- Childhood Cancer Survivors' Quality of Life
- Smoking Behavior and Cessation
- Reproductive tract infections research
- Palliative Care and End-of-Life Issues
- Syphilis Diagnosis and Treatment
- Nicotinic Acetylcholine Receptors Study
- Platelet Disorders and Treatments
- Inflammation biomarkers and pathways
- Lanthanide and Transition Metal Complexes
- Gut microbiota and health
- Digital Mental Health Interventions
- Erythrocyte Function and Pathophysiology
- Sepsis Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- Radiopharmaceutical Chemistry and Applications
- Phagocytosis and Immune Regulation
- Dementia and Cognitive Impairment Research
- Receptor Mechanisms and Signaling
- Family Support in Illness
- Probiotics and Fermented Foods
- Health and Wellbeing Research
- Helicobacter pylori-related gastroenterology studies
- S100 Proteins and Annexins
Kaiser Permanente
2011-2024
Loyola University Chicago
2020
University of California, Los Angeles
2015
VA Greater Los Angeles Healthcare System
2014
University of California, San Francisco
2011
Screening for syphilis with treponemal chemiluminescence immunoassays (CIA) identifies patients discordant serology who are not identified traditional screening methods (eg, CIA-positive, rapid plasma regain (RPR)-negative). We sought to describe the clinical characteristics and management of serology.From August 2007-October 2007, RPR-negative were tested Treponema pallidum particle agglutination assay (TP-PA) at Kaiser Permanente Northern California. Clinical demographic characteristics,...
Sepsis and acute lung injury (ALI) have devastatingly high mortality rates. Both are associated with increased vascular leak, a process regulated by complex molecular mechanisms.We hypothesized that integrin αvβ3 could be an important determinant of leak endothelial permeability in sepsis ALI.β3 subunit knockout mice were tested for after endotracheal LPS, systemic intraperitoneal LPS cecal ligation puncture. Possible contributory effects β3 deficiency platelets other hematopoietic cells...
<h3>Importance</h3> Cigarette smoking leads to upregulation of nicotinic acetylcholine receptors (nAChRs) in the human brain, including common α4β2* nAChR subtype. While subjective aspects tobacco dependence have been extensively examined as predictors quitting with treatment, no studies our knowledge yet reported relationship between extent pretreatment nAChRs and cessation. <h3>Objective</h3> To determine whether degree smokers predicts a standard course treatment. <h3>Design, Setting,...
The reverse sequence algorithm is often used for prenatal syphilis screening by high-volume laboratories, beginning with a treponemal test such as the chemiluminescence immunoassay (CIA), followed testing of CIA-positive (CIA(+)) specimens rapid plasma reagin (RPR). clinical significance discordant serology (CIA(+)/RPR(-)) maternal and neonatal outcomes unknown.From August 2007 to 2010, all pregnant women at Kaiser Permanente Northern California underwent reflexive Treponema pallidum...
Alcohol can potentiate disease in a mouse model of dextran sodium sulfate (DSS) colitis; however, the underlying mechanism remains to be established. In this study, we assessed whether potentiated could related Enterobacteriaceae and Lactobacillus, as changes their relative abundance impact intestinal health. We also barrier is compromised after alcohol DSS it may increase bacterial translocation liver inflammation. Mice were administered followed by binge ethanol or water vehicle,...
Background Timely collection of patient-reported outcomes (PROs) decreases emergency department visits and hospitalizations increases survival. However, little is known about the outcome predictivity unpaid informal caregivers’ reporting using similar clinical assessments. Objective The aim this study to assess whether caregivers adults with cancer adhered a planned schedule for electronically collecting if PROs were associated future events. Methods We developed 2 iPhone apps collect PROs,...
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<sec> <title>BACKGROUND</title> Timely collection of patient-reported outcomes (PROs) decreases emergency department visits and hospitalizations increases survival. However, little is known about the outcome predictivity unpaid informal caregivers’ reporting using similar clinical assessments. </sec> <title>OBJECTIVE</title> The aim this study to assess whether caregivers adults with cancer adhered a planned schedule for electronically collecting if PROs were associated future events....
12026 Background: Informal caregivers are essential partners in the delivery of cancer care, and often can accurately identify report symptoms physical function patients they care for. We assessed whether such reporting by is predictive adverse patient outcomes. Methods: In this prospective study, adult solid on active intravenous systemic therapies their informal were recruited from 18 Kaiser Permanente Northern California centers. Using a study mobile app (TOGETHERCare), completed weekly...