A5103075892- Plant-Microbe Interactions and Immunity
- Plant Pathogens and Fungal Diseases
- Plant Gene Expression Analysis
- RNA modifications and cancer
- Plant Disease Resistance and Genetics
- Plant Pathogenic Bacteria Studies
- Plant Stress Responses and Tolerance
- Computational Drug Discovery Methods
- Genomics and Phylogenetic Studies
- Legume Nitrogen Fixing Symbiosis
- Nematode management and characterization studies
- Plant and animal studies
- Mycorrhizal Fungi and Plant Interactions
- Plant Parasitism and Resistance
- Polysaccharides and Plant Cell Walls
- Receptor Mechanisms and Signaling
- Cholinesterase and Neurodegenerative Diseases
- Plant and Fungal Species Descriptions
- Plant nutrient uptake and metabolism
- Machine Learning in Materials Science
- Plant tissue culture and regeneration
- Photosynthetic Processes and Mechanisms
- Antimicrobial Peptides and Activities
- Cardiac electrophysiology and arrhythmias
- Plant Molecular Biology Research
Nanjing Agricultural University
2019-2024
Liaoning University
2021-2022
Shenyang Agricultural University
2022
Jiaxing University
2018
Succinate dehydrogenase (SDH) is an integral component of the tricarboxylic acid cycle (TCA) and respiratory electron transport chain (ETC), targeted by succinate inhibitors (SDHIs). Fusarium asiaticum a prominent phytopathogen causing head blight (FHB) on wheat. Here, we characterized functions FaSdhA, FaSdhB, FaSdhC1, FaSdhC2, FaSdhD subunits. Deletion or resulted in significant growth defects F. asiaticum. The FaSdhC1 FaSdhC2 deletion mutants exhibited substantial reductions fungal...
Abstract Environmental disasters like drought reduce agricultural output and plant growth. Redox management significantly affects stress responses. An earlier study found that PbPIP1;4 transports H2O2 promotes downstream cascade signaling to restore redox equilibrium. However, this regulatory mechanism requires additional investigation. In search, the AP2 domain-containing transcription factor was isolated by screening Y1H from wild pear (Pyrus betulaefolia) cDNA library, named PbERF3. The...
Abstract Pathogenesis-related proteins (PRs) are essential for plant defense against both biotic and abiotic stresses. However, knowledge regarding PRs in pears remains limited. In this study, 637 PRs, classified into 16 families, were identified Pyrus bretschneideri . Phylogenetic, sequence similarity, secondary structure analyses enabled the classification of several with conserved sequences, including PR-11, PR-8, PR-15, PR-16. Genomic analysis revealed that expansion most PR families...
The genus Tulotis has been classified into the Platanthera in present taxonomic studies since morphological characteristics of this is very similar to that Platanthera. ussuriensis, formerly named as a small terrestrial orchid species and listed wild plant under State protection (category II) China. An improved understanding genomic information will enable future applications conservation strategy well phylogenetic for rare species. objective research was characterize compare chloroplast...
Abstract Pear anthracnose, caused by the fungus Colletotrichum fructicola , is a devastating disease for pear industry. The apoplast, an extracellular compartment outside plasma membrane, plays crucial role in water and nutrient transport, as well plant-microbe interactions. This study aimed to uncover molecular mechanism of leaf apoplastic protein-mediated resistance C. . Apoplast fluid was isolated using vacuum infiltration method, defence-related proteins were identified through protein...
Abstract Pathogenesis-related (PR) genes are key regulators of plant adaptation responses to biotic and abiotic stresses. Family 10 PRs ( PR10 s, also known as major latex proteins) usually induced by pathogens environmental However, the evolutionary trajectory functional divergence gene family in Chinese white pear Pyrus bretschneideri ‘Dangshan Suli’) remain uncharacterized. The presence 61 s was detected across six Rosaceae species. classified into two distinct groups employing...
N6-methylated adenine (m6A) is an emerging epigenetic marker in eukaryotic organisms that plays important role biological functions and enriching genetic information. m6A exerts these via the dynamic interplay among writers, erasers, readers. However, little known about underlying mechanisms of plant growth stress responses. Here, we identified 276 masked regulators from nine Rosaceae species (Pyrus bretschneideri, Pyrus betulifolia, communis, Malus domestica, Fragaria vesca, Prunus avium,...
N6-methylated adenine (m6A) is the most prevalent modification of mRNA methylation and can regulate many biological processes in plants, such as processing, development, stress response. Some studies have increased our understanding its various roles model plants recent years. Nevertheless, distribution m6A impact on regulation plant defense responses against pathogen inoculation are virtually unknown pear. In this study, MeRIP-seq RNA-seq data from healthy inoculated were analyzed to assess...
In recent years, an unusual wilt disease affecting Pyrus pyrifolia has been observed in various regions of Jiangsu, China. This originates from the roots and progresses with distinctive browning patterns along vascular tissues, even extending over two meters above ground. These symptoms set it apart recognized pear diseases typically lead to death affected trees within same or following year. Furthermore, this exhibits a tendency spread neighboring after removal trees, presenting substantial...
Abiotic stresses have had a substantial impact on fruit crop output and quality. Plants evolved an efficient immune system to combat abiotic stress, which employs reactive oxygen species (ROS) activate the downstream defence response signals. Although aquaporin protein encoded by PbPIP1;4 is identified from transcriptome analysis of Pyrus betulaefolia plants under drought treatments, little attention has been paid role PIP ROS in responding pear plants. In this study, we discovered that...
Phytopathogens secrete effectors to promote colonization of their host plants. These modulate immune responses by interfering with various pathways, but little is known about biochemical activities. Several recent reports indicate that some phytopathogen have Nudix hydrolase activity, including Avr3b from Phytophthora sojae (Dong et al., 2011), AvrM14 Melampsora lini (McCombe 2023), and RipN Ralstonia solanacearum (Sun 2019). hydrolases contain the conserved motif GxxxxxExxxxxxxREUxEExGU...
Abstract At present, drug toxicity has become a critical problem with heavy medical and economic burdens. acLQTS (acquired Long QT Syndrome) is acquired cardiac ion channel disease caused by drugs blocking the hERG channel. Therefore, it necessary to avoid cardiotoxicity in design computer models have been widely used fix this plight. In study, we present molecular fingerprint based on dynamic simulation uses combined other fingerprints (multi-dimensional fingerprints) predict of compounds....
Pathogenesis-related (PR) proteins play a crucial role in plant defense against diverse threats, including biotic and abiotic factors. These versatile exhibit wide range of functions such as chitinases, peroxidases, antimicrobial agents, hydrolases, protease inhibitors. However, the knowledge concerning PRs pears is constrained. In this study, total 637 PR categorized into 17 families were discerned Pyrus bretschneideri. Through phylogenetic, sequence similarity, secondary structure...
Objective To study the correlation of prognosis Icotinib administration with expression levels F-box and WD repeat domain-containing 7(FBW7) myeloid cell leukemia-1(MCL-1) in peripheral blood elderly patients advanced non-small-cell lung cancer. Methods A total 76 aged 60 years or over diagnosed cancer(NSCLC)with EGFR-sensitive mutations under treatment were enrolled this study.FBW7 MCL-1 mRNA detected by real-time quantitative PCR(RT-QPCR). The FBW7 clinical histological parameters,...