A5074987490- Pulmonary Hypertension Research and Treatments
- Drug-Induced Hepatotoxicity and Protection
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Medical Imaging and Pathology Studies
- Heart Failure Treatment and Management
- Diabetes Treatment and Management
- Clostridium difficile and Clostridium perfringens research
- Gastrointestinal Bleeding Diagnosis and Treatment
- Innovative Human-Technology Interaction
- Autoimmune and Inflammatory Disorders
- Veterinary medicine and infectious diseases
- Retinal Diseases and Treatments
- Autoimmune Bullous Skin Diseases
- Cardiovascular Function and Risk Factors
- Medical and Biological Ozone Research
- Blood Coagulation and Thrombosis Mechanisms
- Organ Transplantation Techniques and Outcomes
- Esophageal and GI Pathology
- Fungal Infections and Studies
- Chemotherapy-induced organ toxicity mitigation
- Impact of Technology on Adolescents
- Vitamin C and Antioxidants Research
- Drug Transport and Resistance Mechanisms
- Retinal and Optic Conditions
University of Connecticut
2022-2024
UConn Health
2022-2024
Connecticut Health Foundation
2023
University of Hartford
2022
Larkin University
2021
Simon Fraser University
2016
Mobile devices have begun to raise questions around the potential for overuse when in presence of family or friends. As such, we conducted a diary and interview study understand how people use mobile others at home, this shapes their behavior household dynamics. Results show that members become frustrated do non-urgent activities on phones others. Yet often guess what are doing because personal nature devices. In some cases, developed strategies provide greater sense activity awareness...
Background Pulmonary hypertension (PH) leads to increased morbidity and mortality in interstitial lung disease (ILD). While the INCREASE trial highlighted use of inhaled prostacyclin PH-ILD patients, such therapy may be inadequate when right ventricular failure (RVF) is also present. In this study, we report intravenous three patients stabilise (RV) function, with a subsequent transition maintenance prostacyclin. Methods We evaluated consecutive RVF. RV afterload pulmonary vascular...
Abstract Pulmonary hypertension (PH) is a frequent complication in patients with interstitial lung disease (ILD); its occurrence results significant morbidity and mortality. Currently approved treatment options for PH-ILD include inhaled prostacyclin therapy, although this approach may be insufficient who have developed concomitant right ventricular failure. Moreover, there no available algorithm regarding the optimal therapy timing of transplant referral based on severity. In study, we...
Right ventricular failure (RVF) in pre-capillary pulmonary hypertension (PH) is associated with high morbidity and mortality. While mean arterial pressure (MAP) goals have been well established critical care literature, the optimal MAP target for patients RVF secondary to PH remains unknown. The objective of this study was evaluate difference outcomes between who were managed different targets. We retrospectively analyzed records 60 admitted intensive unit decompensated PH. stratified into...
Introduction: Temozolomide is an oral alkylating agent used with radiotherapy as a first line treatment for glioblastoma. Commonly known side effects of temozolomide include nausea, fatigue, and bone marrow suppression. The narrow effect profile makes it preferred (3). We present rare case drug induced liver injury temozolomide. Case Description/Methods: A 71 year old man glioblastoma undergoing TRIDENT clinical trial (tumor treating fields + radiation temozolomide) presented generalized...
Introduction: Liraglutide is a GLP-1 receptor agonist commonly used for treatment of diabetes mellitus and increasingly weight loss. We present unique case drug-induced liver injury with autoimmune features (AI-DILI) secondary to Liraglutide. AI-DILI characterized by accompanied laboratory evidence autoimmunity induced medication. Key include resolution after the withdrawal offending medication use short-term immunosuppressive therapy, without relapse upon taper. Case Description/Methods: A...
1University of Connecticut Internal Medicine Program 2University School 3Hartford Healthcare
Introduction: Intussusception is when part of the bowel invaginates or telescopes into itself; commonly seen in infants 3 months to 2 years old. The overall incidence adult intussusception 2-3 cases/1,000,000 population/year. It considered a medical abdominal emergency as it may result small obstruction, peritonitis perforation. Case Description/Methods: A 26 year old female with no history presented vomiting, colicky pain, and watery diarrhea for two days. Despite being recently treated...
Introduction: We present a case of chronic unexplained thrombocytopenia and incidental thromboembolism in patient with newly diagnosed obstructive pulmonary disease (COPD). He was admitted to the hospital for assessment anticoagulant tolerance workup his which resulted diagnosis alpha-1 antitrypsin (AAT) deficiency. Case Description/Methods: A 57-year-old non-smoker male recently COPD undergoing thrombocytopenia. computed tomography (CT) chest revealed bilateral emboli, mild hepatic...
Introduction: Traditionally, lower gastrointestinal bleed (LGIB) patients tend to have a benign clinical course compared those with upper (UGIB) leading the over-utilization of resources in UGIB. However, recent studies reported similar outcomes such as readmission and mortality rates, thereby challenging this view. Our study aimed compare between two groups. Methods: This is post-hoc analysis retrospective on admitted their primary diagnosis higher level care from March, 2015 - 2021....
Introduction: Early endoscopic intervention (within 6 hours of admission) in patients with gastrointestinal bleeding (GIB) increases overall mortality but does not improve the mortality, length stay (LOS), or transfusion requirement lower GIB, while reducing LOS upper GIB. We aimed to study prognosis undergoing < 1 day compared ≥ day. Methods: This is a single-center retrospective cohort analysis admitted Intermediate unit and ICU GIB as their primary diagnosis (03/2015 – 03/2021). Medical...
Introduction: Gastrointestinal (GI) bleeding affects 30-40 per 100,000 hospitalized patients annually. Many of these can have severe with hemodynamic instability and rapid clinical deterioration, often requiring higher levels care such as intermediate units (IU) or intensive (ICU). This study aimed to compare various risk stratification tools patient outcomes find which best help providers triage most appropriately on admission. Methods: is a single-center retrospective cohort analysis...