Shan Shan

ORCID: 0000-0003-4928-588X
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About
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Research Areas
  • Liver Disease Diagnosis and Treatment
  • Biosensors and Analytical Detection
  • Advanced biosensing and bioanalysis techniques
  • Hepatitis B Virus Studies
  • Hepatitis C virus research
  • Neonatal Respiratory Health Research
  • Liver Diseases and Immunity
  • MicroRNA in disease regulation
  • Energy, Environment, Economic Growth
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Morphological variations and asymmetry
  • Diet, Metabolism, and Disease
  • Market Dynamics and Volatility
  • Cancer-related molecular mechanisms research
  • Mobile Ad Hoc Networks
  • Evolution and Paleontology Studies
  • Wildlife Ecology and Conservation
  • Genomics and Chromatin Dynamics
  • RNA modifications and cancer
  • Natural product bioactivities and synthesis
  • Digital Marketing and Social Media
  • Inflammasome and immune disorders
  • Polysaccharides and Plant Cell Walls
  • Seaweed-derived Bioactive Compounds
  • Autophagy in Disease and Therapy

Shandong University
2013-2025

Shanghai Sixth People's Hospital
2017-2025

Shanghai Jiao Tong University
2017-2025

Shandong Jiaotong University
2010-2024

Beijing Friendship Hospital
2018-2024

Capital Medical University
2016-2024

The University of Texas at Dallas
2009-2024

University of Wisconsin–Madison
2023-2024

Coventry University
2021-2024

Jiangxi Normal University
2019-2024

After the Paris Climate Conference (COP21), many countries start progressing towards carbon neutrality targets. In doing so, green technology innovations (GTIs) and clean energy are essential factors that can help to achieve goal. Therefore, this paper examines linkages between innovation renewable dioxide emissions based on STIRPAT model in Turkey during time of 1990–2018. The study used testing like “unit-root” verify variables' integrative properties containing information for structural...

10.1016/j.jenvman.2021.113004 article EN cc-by Journal of Environmental Management 2021-06-16

Abstract Large‐scale digitization projects such as #ScanAllFishes and oVert are generating high‐resolution microCT scans of vertebrates by the thousands. Data from these shared with community using aggregate 3D specimen repositories like MorphoSource through various open licenses. We anticipate an explosion quantitative research in organismal biology convergence available data methodologies to analyse them. Though available, road a series images analysis is fraught challenges for most...

10.1111/2041-210x.13669 article EN Methods in Ecology and Evolution 2021-07-14

Endometriosis, a chronic disorder characterised by the presence of endometrial-like tissue outside uterus, is associated with iron overload and oxidative stress in lesion. Although it well established that can trigger ferroptosis, results previous studies on ferroptosis resistance endometriotic lesions are paradoxical. Here, we found some stromal cells cyst walls were contact fluid underwent ferroptosis. Surprisingly, endometrial cell triggered production angiogenic, inflammatory growth...

10.1038/s41420-022-00821-z article EN cc-by Cell Death Discovery 2022-01-17

Long noncoding RNAs participate in the progression and initiation of non-small cell lung cancer (NSCLC), although mechanism remains unknown. The lncRNA identified as small nucleolar RNA host gene 1 (SNHG1) is a novel that increased multiple human cancers; however, regulatory requires further investigation. In this study, we discovered SNHG1 was markedly up-regulated NSCLC tissues cells silencing decreased tumor volumes. Moreover, explored its found directly bound to microRNA (miRNA)-145–5p,...

10.1096/fj.201701237rr article EN The FASEB Journal 2018-02-21

H2A.Z is a highly conserved histone variant in all species. The chromatin deposition of specifically catalyzed by the yeast remodeling complex SWR1 and its mammalian counterpart SRCAP. However, mechanism which preferentially recognized non-histone proteins remains elusive. Here we identified Anp32e, novel higher eukaryote-specific chaperone for H2A.Z. Anp32e associates with H2A.Z-H2B dimers rather than H2A-H2B vitro vivo dissociates non-nucleosomal aggregates formed DNA H2A-H2B. We...

10.1038/cr.2014.30 article EN cc-by-nc-nd Cell Research 2014-03-11

Purpose The purpose of this paper is to examine the effect natural resources, market size and five major institutional factors (voice accountability; political stability absence violence; regulatory quality; rule law control corruption) on Chinese foreign direct investment (FDI) in Africa. Design/methodology/approach This study uses regression analysis panel data across 22 countries for period 2008-2014. Findings Natural resources did not play a significant role attracting investments, but...

10.1108/cpoib-11-2016-0055 article EN Critical Perspectives on International Business 2018-01-26

Abstract MicroRNA-155 (miR-155) was previously found involved in the development of systemic lupus erythematosus (SLE) and other autoimmune diseases inflammatory response; however, detailed mechanism miR-155 SLE is not fully understood. To explore vivo role pathogenesis SLE, miR-155–deficient Faslpr/lpr (miR-155−/−Faslpr/lpr) mice were obtained by crossing miR-155−/− mice. Clinical features such as glomerulonephritis, autoantibody levels, immune system cell populations compared between...

10.4049/jimmunol.1403028 article EN The Journal of Immunology 2015-04-25

The Akt pathway is a central regulator that promotes cell survival in response to extracellular signals. Depletion of SIRT7, an NAD+-dependent deacetylase the least-studied sirtuin, known significantly increase activity mice through unknown mechanisms. In this study, we demonstrate SIRT7 depletion breast cancer cells results hyper-phosphorylation and increases following genotoxic stress. Mechanistically, specifically interacts with deacetylates FKBP51 at residue lysines 28 155 (K28 K155),...

10.1016/j.celrep.2017.01.009 article EN cc-by-nc-nd Cell Reports 2017-01-01

In this work, a green enzyme–linked immunosorbent assay (ELISA) based on the single-stranded binding protein (SSB)-assisted aptamer was designed for biosensing applications. Combined with biotin–streptavidin (SA) system and high catalytic activity of horseradish peroxidase (HRP), SSB-assisted sensor applied detection aflatoxin B1, ochratoxin A, zearalenone. novel ELISA, mycotoxin–protein conjugations were replaced by SSB to avoid hazard mycotoxin, whereas antibodies complex tedious...

10.1021/acs.analchem.0c01073 article EN Analytical Chemistry 2020-05-14

Summary Tillering is a significant agronomic trait in wheat which shapes plant architecture and yield. Strigolactones ( SL s) function inhibiting axillary bud outgrowth. The roles of s the regulation outgrowth have been described model species, including rice Arabidopsis . However, role genes remains elusive due to size complexity genomes. In this study, TaD27 wheat, orthologs D27 encoding an enzyme involved biosynthesis, were identified. ‐ RNA i plants had more tillers, TaD27‐B OE fewer...

10.1111/pbi.13220 article EN cc-by-nc Plant Biotechnology Journal 2019-07-27

Abstract Long non‐coding RNA s (lnc s) have emerged as new and important regulators of pathological processes including tumour development. In this study, we demonstrated that differentiation antagonizing non‐protein coding ( DANCR ) was up‐regulated in lung adenocarcinoma ADC the knockdown inhibited cell proliferation, migration invasion restored apoptosis rescued; cotransfection with a miR‐496 inhibitor reversed these effects. Luciferase reporter assays showed directly modulated ;...

10.1111/jcmm.13420 article EN cc-by Journal of Cellular and Molecular Medicine 2017-12-20

Various pathogens may coexist in one sample; however, detection methods that rely on traditional selective culture media or immune agents designed specifically for a certain target are unsuitable multiple targets. It is important to develop simultaneous and sensitive method pathogens. Here, multicolor ultrasensitive enzyme-linked immunosorbent assay (ELISA) platform based the fluorescence hybridization chain reaction (HCR) was developed. In assay, concatemers formed as signal amplifiers...

10.1021/acs.jafc.9b03414 article EN Journal of Agricultural and Food Chemistry 2019-07-31
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