A5009873299- Immune Response and Inflammation
- Asthma and respiratory diseases
- Neonatal Respiratory Health Research
- Dermatology and Skin Diseases
- Essential Oils and Antimicrobial Activity
- Advancements in Transdermal Drug Delivery
- Phagocytosis and Immune Regulation
- S100 Proteins and Annexins
- Immune cells in cancer
- IL-33, ST2, and ILC Pathways
- Bee Products Chemical Analysis
- Immune responses and vaccinations
- Pediatric health and respiratory diseases
Universidade de São Paulo
2021-2023
Universidade de Ribeirão Preto
2023
Propolis is a natural product produced by bees that primarily used in complementary and alternative medicine has anti-inflammatory, antibacterial, antiviral, antitumoral biological properties. Some studies have reported the beneficial effects of propolis models allergic asthma. In previous study, our group showed green treatment reduced airway inflammation mucus secretion an ovalbumin (OVA)-induced asthma model resulted increased regulatory T cells (Treg) polymorphonuclear myeloid-derived...
There is evidence that IL-22 and IL-17 participate in the pathogenesis of allergic asthma. To investigate role IL-22, we used deficient mice (IL-22 KO) sensitized challenged with ovalbumin (OVA) compared wild type (WT) animals exposed to OVA. KO OVA showed a decreased number frequency eosinophils, IL-5 IL-13 airways, reduced mucus production pulmonary inflammation. In addition, exhibited percentage lung CD11c+CD11b+ cells increased apoptosis eosinophils. Th17 cell transfer generated from...
Abstract The alarmin S100 calcium-binding protein A9 (S100A9) plays a role in the immunopathology of lung diseases such as asthma and pneumonia. We hypothesized that acute pneumonia induced by S. pneumoniae exacerbates through S100A9 induction increase neutrophilic inflammation NET production. C57BL/6 Wild Type (WT) animals mice deficient for expression (S100A9 −/−) were sensitized challenged with ovalbumin (OVA) infected or not during challenge. In WT mice, comorbidity resulted significant...