A5101814868- Neonatal Respiratory Health Research
- Congenital Diaphragmatic Hernia Studies
- Respiratory Support and Mechanisms
- Pulmonary Hypertension Research and Treatments
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Ultrasound in Clinical Applications
- Congenital Heart Disease Studies
- Kawasaki Disease and Coronary Complications
- Neuroscience of respiration and sleep
- Inflammasome and immune disorders
- Congenital Anomalies and Fetal Surgery
- Circular RNAs in diseases
- Immunodeficiency and Autoimmune Disorders
- RNA modifications and cancer
- Esophageal and GI Pathology
- Systemic Lupus Erythematosus Research
- Cardiovascular Issues in Pregnancy
- Tracheal and airway disorders
- Cardiovascular Conditions and Treatments
- Autoimmune and Inflammatory Disorders Research
- Infant Development and Preterm Care
- Coronary Artery Anomalies
- Pediatric Hepatobiliary Diseases and Treatments
- 3D Shape Modeling and Analysis
Zhejiang University
2018-2022
Hangzhou First People's Hospital
2013-2022
Hangzhou Cancer Hospital
2020
Nanjing Medical University
2010-2020
Zhejiang Chinese Medical University
2017
Nanjing Maternity and Child Health Care Hospital
2013
Anemia and the need for transfusion of packed red blood cells (PRBCs) are common in preterm infants. PRBC increases oxygen carrying capacity hemoglobin may result higher rates organ dysfunction. To determine whether infants is associated with an increased incidence bronchopulmonary dysplasia (BPD), this retrospective study was performed on neonates birth weights ≤ 1,500 g or gestational age 32 weeks admitted from August, 2008 to November, 2013. Infants who received before diagnosis BPD those...
Kawasaki disease (KD) is an autoimmune in which the medium-sized blood vessels throughout body become inflamed. The increased evidences showed that TNF-α was association with vascular inflammation KD patients. However detailed mechanism still unclear. Recent studies indicated abnormal expressed long non-coding RNAs (LncRNAs) involved many diseases. Thus purpose of this study to explore role lncRNAs and find out new target for treatment. In study, firstly we verified overexpressed patients,...
Increasing evidence has indicated that aberrant expression of miRNAs been shown to be strongly implicated in the initiation and progression glioblastoma. Here, we identified a novel tumor suppressive miRNA, miR-564, investigated its role therapeutic effect for We showed miR-564 was down-regulated human glioblastoma tissues cell lines. Introduction dramatically inhibited growth invasion cells. Subsequent experiments revealed Transforming factor-β1 (TGF-β1) direct functional target...
Objectives . To evaluate the predictive characteristics of KL-6 and CC16 for bronchopulmonary dysplasia (BPD) in preterm infants, either independently or combination. Study Design This prospective cohort study was performed from 2011 to 2013 with neonates gestational age ≤32 weeks birth weight ≤1500 g. Serum levels were determined 7 14 days after birth. Results Seventy-three infants studied. BPD identified 24 these infants. After adjusting potential confounders, serum concentrations found be...
BACKGROUND:Patent ductus arteriosus (PDA) is a common congenital cardiac abnormality in premature infants. In low-birth-weight infants weighing less than 2500 g, if the PDA continues to open, abnormal circulation hemodynamics and pulmonary edema may occur. This study aimed investigate role of lung ultrasound score assessment low-weight neonates with PDA. MATERIAL AND METHODS:Two hundred twenty-one low birth weight were selected as subjects, children observation group, closed control group....
Patent ductus arteriosus (PDA) is a common congenital heart abnormality in preterm neonates with high incidence very low birth weights. When PDA persists, interstitial lung water content increases, which could lead to abnormal circulation hemodynamics and pulmonary edema. It important perform early reliable assessment of low-weight persistent PDA.
Abstract Background Recently, the role of several microRNAs (miRNAs or miRs) in pulmonary diseases has been described. The molecular mechanisms by which miR-214 is possibly implicated bronchopulmonary dysplasia (BPD) have not yet addressed. Hence, this study aimed to investigate a putative alveolarization among preterm neonates with BPD. Methods Microarray-based gene expression profiling data from BPD was employed identify differentially expressed genes. A neonatal rat model induced...
Neonatal lupus erythematosus (NLE) is an infrequent disease caused by transplacental maternal autoantibodies. The most common effects of NLE include cutaneous involvement and congenital heart block (CHB), although it might involve multiple organs, such as the liver, lungs, blood, nervous or digestive systems. Izmirly PM1 Tonello et al recently reported manifestations neonatal risk subsequent CHB. serious complication complete atrioventricular (AV) block.We experienced 2 cases that were...
This study investigates the effect of overexpression placental growth factor (PGF) and hyperoxia on lung development determines whether anti-PGF antibody ameliorates hyperoxia-mediated impairment in newborn rats. After exposure to normoxic conditions for seven days, rats subjected normoxia were intraperitoneally or intratracheally injected with physiological saline, adenovirus-negative control (Ad-NC), adenovirus-PGF (Ad-PGF) create Normoxia, Normoxia+Ad-NC, Normoxia+Ad-PGF groups,...
To evaluate the effect of intestinal carbapenem-resistant Enterobacteriaceae (CRE) active screening combined with enhanced intervention in prevention and control nosocomial infection patients admitted to hematological ward.
Abstract The aim of this study was to evaluate KL-6 and CC16 levels their correlation with neurodevelopmental outcome among very low birth weight pre-term infants at 12 months corrected age. This prospective cohort performed from 2011 2013 by enrolling neonates gestational age ≤ 32 weeks 1500 g. Serum were determined 7 days after neurodevelopment evaluated using Gesell Mental Developmental Scales. Of the 86 eligible infants, 63 completed follow-up, which 15 had bronchopulmonary dysplasia. At...