A5005046608- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Metal complexes synthesis and properties
- Ferrocene Chemistry and Applications
- Click Chemistry and Applications
- Crystal structures of chemical compounds
- Nanoplatforms for cancer theranostics
- Lanthanide and Transition Metal Complexes
- Magnetism in coordination complexes
- Metal-Organic Frameworks: Synthesis and Applications
- Crystallography and molecular interactions
- Drug Transport and Resistance Mechanisms
- Luminescence and Fluorescent Materials
- Synthesis and Characterization of Heterocyclic Compounds
- Advanced biosensing and bioanalysis techniques
- Nanoparticle-Based Drug Delivery
- Photodynamic Therapy Research Studies
- Synthesis and biological activity
- Transition Metal Oxide Nanomaterials
- Advanced Nanomaterials in Catalysis
- Advanced Queuing Theory Analysis
- Supercapacitor Materials and Fabrication
- Advanced SAR Imaging Techniques
- Microwave Imaging and Scattering Analysis
- Conducting polymers and applications
Guangxi Normal University
2023-2025
Zhejiang University of Technology
2024-2025
Materials Science & Engineering
2025
Southeast University
2014-2024
State Key Laboratory of Millimeter Waves
2019-2024
Beijing Sport University
2004-2024
State Key Laboratory of High Performance Civil Engineering Materials
2024
Technical University of Denmark
2024
University of the Witwatersrand
2024
China Academy of Engineering Physics
2023
Abstract Conventional buildings consume about 40% of global energy, smart window technologies have been developed for sunlight modulation and energy management. Most current windows change from transparent to opaque as the temperature rises, which is detrimental indoor lighting at daytime or privacy protection night. In this work, a versatile thermochromic hydrogel system by introducing sodium dodecyl sulfate (SDS) micelles into crosslinked copolymer hydrophilic acrylamide hydrophobic...
Effective photosensitizers are of particular importance for the widespread clinical utilization phototherapy. However, conventional usually plagued by short-wavelength absorption, inadequate photostability, low reactive oxygen species (ROS) quantum yields, and aggregation-caused ROS quenching. Here, we report a near-infrared (NIR)-supramolecular photosensitizer (RuDA) via self-assembly an organometallic Ru(II)-arene complex in aqueous solution. RuDA can generate singlet (1O2) only aggregate...
Flexible zinc-ion batteries (ZIBs) with high capacity and long cycle stability are essential for wearable electronic devices. Hydrogel electrolytes have been developed to provide ion-transfer channels while maintaining the integrity of ZIBs under mechanical strain. However, hydrogel matrices typically swollen aqueous salt solutions increase ionic conductivity, which can hinder intimate contact electrodes reduce properties. To address this, a single-Zn-ion-conducting electrolyte (SIHE) is by...
To develop a potential theranostic metal agent to reverse the resistance of cancer cells cisplatin and effectively inhibit tumor growth metastasis, we proposed design cyclometalated iridium (Ir) complex based on properties environment (TME). end, designed synthesized series Ir(III) 2-hydroxy-1-naphthaldehyde thiosemicarbazone complexes by modifying hydrogen atom(s) N-3 position compounds structure dimers then investigated their structure–activity structure–fluorescence relationships obtain...
Abstract Iridium(III) complexes are an important group of photosensitizers for photodynamic therapy (PDT). This work constructs a donor–acceptor–donor structure‐based iridium(III) complex (IrDAD) with high reactive oxygen species (ROS) generation efficiency, negligible dark toxicity, and synergistic PDT photothermal (PTT) effect under near‐infrared (NIR) stimulation. self‐assembles into metallosupramolecular aggregates unique aggregation‐induced behavior. Compared conventional...
A facile “one-step” strategy was developed for in situ encapsulating liquid metal (LM) though 3D Ti 3 C 2 T x –MXene skeleton. The “inside–outside” design endows the LM-MXene anode with enhanced lithium storage performance.
Abstract Hydrogel actuators have shown great promise in underwater robotic applications as they can generate controllable shape transformations upon stimulation due to their ability absorb and release water reversibly. Herein, a photoresponsive anisotropic hydrogel actuator is developed from poly(N‐isopropylacrylamide) (PNIPAM) gold‐decorated carbon nitride (Au/g‐C 3 N 4 ) nanoparticles. Carbon nanoparticles endow with photocatalytic properties, while reorientation mobility driven by the...
Development of highly efficient near-infrared (NIR)-excited photosensitizers is hampered by the fast nonradiative vibrational relaxation process regulated energy gap law. Here, from fundamental perspective we propose that intermolecular coupling well-designed has potential to facilitate exciton delocalization and hence reduce exciton-vibration coupling, thereby boosting their phototherapeutic efficacy via inhibition pathway. Such conceived NIR-excited metallo-photosensitizers (IrHA1 IrHA2)...
To develop the next-generation Pt drug with remarkable activity and low toxicity to maximally inhibit tumor growth, we optimized a Pt(II) thiosemicarbazone compound (C4) cytotoxicity SK-N-MC cells then constructed new human serum albumin-C4 (HSA-C4) complex delivery system. The in vivo results showed that C4 HSA-C4 have therapeutic efficiency almost no toxicity; they induced apoptosis inhibited angiogenesis. This system potential as practical drug. study could pave way for developing...
To obtain next-generation metal drugs that can overcome the deficiencies of platinum (Pt) and treat cancer more effectively, we proposed to develop a multitargeted palladium (Pd) agent tumor microenvironment (TME) based on specific residue(s) human serum albumin (HSA). this end, optimized series Pd(II) 2-benzoylpyridine thiosemicarbazone compounds Pd (5b) with significant cytotoxicity. The HSA-5b complex structure revealed 5b bound hydrophobic cavity in HSA IIA subdomain then His-242...
To integrate targeted diagnosis and treatment of cancer, we proposed to develop a gadolinium (Gd) agent based on the properties apoferritin (AFt). this end, not only optimized series Gd(III) 8-hydroxyquinoline-2-carboxaldehyde-thiosemicarbazone compounds obtain compound (C4) with remarkable T1-weighted magnetic resonance imaging (MRI) performance cytotoxicity cancer cells in vitro but also constructed an AFt–C4 nanoparticle (NP) delivery system. Importantly, NPs improved targeting ability C4...
To develop next-generation metal drugs with high efficiency and low toxicity for targeting inhibition of gastric tumor growth metastasis, we not only optimized a series ruthenium (Ru, III) 2-hydroxy-1-naphthaldehyde thiosemicarbazone complexes to obtain Ru(III) complex (4b) remarkable cytotoxicity in vitro but also constructed 4b-decitabine (DCT)/liposome (Lip) delivery system (4b-DCT-Lip). The vivo results showed that 4b-DCT-Lip had stronger capacity inhibit metastasis than 4b-DCT addressed...
To develop a next-generation metal agent and dual-agent multitargeted combination therapy, we developed copper (Cu) compound based on the properties of human serum albumin (HSA)–indomethacin (IND) complex to remodel tumor microenvironment (TME). We optimized series Cu(II) isopropyl 2-pyridyl ketone thiosemicarbazone compounds obtain (C4) with significant cytotoxicity then constructed an HSA–IND–C4 (HSA–IND–C4) delivery system. IND C4 bind hydrophobic cavities IB IIA domains HSA,...
Eutectic gallium-indium liquid metal (EGaIn-LM), with a considerable capacity and unique self-healing properties derived from its intrinsic nature, gains tremendous attention for lithium-ion batteries (LIBs) anode. However, the fluidity of LM can trigger continuous consumption electrolyte, liquid-solid transition during lithiation/de-lithiation process may result in rupture solid electrolyte interface (SEI). Herein, is employed as an initiator to situ assemble 3D hydrogel dynamically...
Abstract The integration of electrochromic devices and energy storage systems in wearable electronics is highly desirable yet challenging, because self‐powered often require an open system design for continuous replenishment the strong oxidants to enable coloring/bleaching processes. A device has been developed with a close configuration by integrating Zn/MnO 2 ionic battery into Prussian blue (PB)‐based system. Zn MnO electrodes, as dual shared former one can reduce PB electrode white (PW)...
A novel 3-D (3,6)-connected topological architecture, obtained by reacting Cd(ClO4)2 x 6H2O with Htrtr (Htrtr = 3-(1,2,4-triazole-4-yl)-1H-1,2,4-triazole) under solvothermal conditions, presents a non-centrosymmetric polar packing arrangement, resulting in strong second harmonic generation (SHG) response and ferroelectric property.
Three organometallic Ru(arene) compounds bearing 7-hydroxycoumarin have been designed and synthesized. Resulting Ru(II) complexes 2–4 showed potent cytotoxicity against the tested cancer cell lines, much higher than either ligand L1 or unfunctionalized complex 1 alone. Further study indicated can activate expression of Bax, induce cytochrome c release from mitochondria, finally caspase-3, hinting that these probably apoptosis by mitochondrial pathway. Additional molecular docking potential...
Subtle ligand modifications on ruthenium arene complexes can lead to different mechanisms of action and result in significant changes the anticancer efficacy. Herein, four novel dinuclear ruthenium(II) were designed prepared. In vitro tests indicated that 1–3 displayed moderate antiproliferative activity against tested cancer cells, while cytotoxicity complex 4 is superior or comparable cisplatin. Further studies 1–4 induce cell death through DNA interaction a...
Abstract To enhance the areal energy density of current flexible storage devices, hybrid capacitors combining advantages supercapacitors and batteries are proposed further enhanced by incorporating 3D interdigital structure design. However, uneven electric field distribution hindered ion diffusion kinetics due to non‐electroactive components in these devices limit enhancement electrochemical performances when expanding electrodes longitudinally. Herein, hydrogels with high ionic conductivity...
The limited utilisation of epoxy asphalt primarily stems from its inherent brittle cracking behaviour. This investigation aims to mitigate this issue by introducing styrene–butadiene-styrene/crumb rubber modified (SBS/CRMA). Furthermore, research assesses the influence SBS/CRMA on curing behaviour (EA) and low-temperature fracture characteristics concrete (EAC). EA was systematically examined using diverse analytical techniques, including attenuated total reflectance fourier transform...
Hypoxia-targeting Pt(<sc>iv</sc>) prodrugs inhibit the expression of HIF-1α with high antitumor efficacy and low toxicity.