A5103069867- Meningioma and schwannoma management
- Vascular Malformations Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Neurofibromatosis and Schwannoma Cases
- Neonatal and fetal brain pathology
- Facial Nerve Paralysis Treatment and Research
- Spinal Fractures and Fixation Techniques
- Traumatic Brain Injury and Neurovascular Disturbances
- Anatomy and Medical Technology
- Spinal Dysraphism and Malformations
- Cerebrovascular and Carotid Artery Diseases
- Trigeminal Neuralgia and Treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Surgical Simulation and Training
- Aortic Disease and Treatment Approaches
- Neurosurgical Procedures and Complications
- Nerve Injury and Rehabilitation
- Connexins and lens biology
- Retinopathy of Prematurity Studies
- Cerebrospinal fluid and hydrocephalus
- Radiation Dose and Imaging
- Moyamoya disease diagnosis and treatment
- Oropharyngeal Anatomy and Pathologies
- Mitochondrial Function and Pathology
- Aortic aneurysm repair treatments
Neurological Surgery
2019-2025
University of Oklahoma
2024-2025
Children's Hospital of Oklahoma
2024-2025
University of Oklahoma Health Sciences Center
2024-2025
University of Wisconsin–Madison
2019-2024
University of Bern
2024
Wisconsin Division of Public Health
2022
UW Health University Hospital
2019-2020
OBJECTIVE The COVID-19 pandemic posed significant global challenges, particularly in its disruption of surgical education, training, and research. University Wisconsin (UW)–Madison Microneurosurgery Laboratory, an internationally recognized training center, had to rapidly adapt continue mission amid restrictions. In this study the authors evaluated their laboratory’s response during after pandemic, focusing on challenges encountered, innovative strategies used, impact ongoing operations...
OBJECTIVE Spinal column shortening (SCS) is an emerging alternative to traditional untethering in cases of secondary tethered cord syndrome. It was originally described and applied adult patients with spinal dysraphism. In the more recent past, SCS has been used pediatric patients. A comparison between undergoing not performed previously. METHODS retrospective analysis conducted on 19 (11 children, 8 adults) who underwent procedures from November 30, 2020, July 21, 2024, at University...
Abstract Background Neonatal hypoxia ischemia (HI) related brain injury is one of the major causes life-long neurological morbidities that result in learning and memory impairments. Evidence suggests male neonates are more susceptible to detrimental effects HI, yet mechanisms mediating these sex-specific responses neural remain poorly understood. We previously tested treatment with a small molecule agonist tyrosine kinase B receptor (TrkB), 7,8-dihydroxyflavone (DHF) following neonatal HI...
BACKGROUND AND OBJECTIVES: In low- and middle-income countries (LMICs), approximately 5 million essential neurosurgical operations per year remain unaddressed. When compared with high-income countries, one of the reasons for this disparity is lack microsurgery training laboratories neurosurgeons trained in microsurgical techniques. 2020, we founded Madison Microneurosurgery Initiative to provide no-cost, accessible, sustainable opportunities health care professionals from LMICs their...
Abstract Brachial plexus injury (BPI) occurs when the brachial is compressed, stretched, or avulsed. Although rodents are commonly used to study BPI, these models poorly mimic human BPI due discrepancy in size. The objective of this was compare between and Wisconsin Miniature Swine TM (WMS ), which approximately weight an average (68–91 kg), determine if swine would be a suitable model for studying mechanisms treatments. To analyze gross anatomy, WMS plexuses were dissected both anteriorly...
The variability of severity in hypoxia-ischemia (HI)-induced brain injury among research subjects is a major challenge developmental research. Our laboratory developed novel scoring tool based on our gross pathological observations during hippocampal extraction. hippocampi received scores 0–6 with 0 being no and 6 severe post-HI. exposed to sham surgery were grouped as having injury. We have validated the T2-weighted MRI analysis percent hippocampal/hemispheric tissue loss cell...
Abstract BACKGROUND Determining if paraclinoid aneurysms are intradural or extradural is critical for surgical planning. OBJECTIVE To create an easily reproducible diagnostic method based on bony anatomy that precisely locates the distal dural ring (DDR) to determine position of as intradural, transitional, extradural. METHODS Bilateral anatomic dissections 10 cadaveric heads (20 sides) were performed evaluate DDR anatomy. We observed a plane reflects passes through 4 landmarks: 1) The...
This study investigates the effects of early surgery in aneurysmal subarachnoid hemorrhage (SAH) on outcome and postoperative complications.This retrospective includes 250 patients who presented to a teaching hospital with SAH underwent aneurysm clipping during 10-year period.212 (84.8%) early, 38 (15.2%) late surgery.Presenting symptoms, clinical neuroradiological findings, outcomes were reviewed.The severity was assessed using World Federation Neurosurgical Societies (WFNS) scale Fisher's...
OBJECTIVE Time-driven activity-based costing (TDABC) is a method used in cost accounting that has gained traction health economics to identify value optimization initiatives. It measures time, assigns time increments spent on patient, and integrates the of material human resources utilized each episode care. In this study, authors report first use TDABC evaluate costs pediatric neurosurgical practice. METHODS A clinical pathway was developed with multifunction team. survey among care team...
BACKGROUND: Cerebral intraventricular hemorrhage (IVH) is a major cause of neurodevelopmental impairment in preterm infants.IVH characterized by vessel rupture and rapid accumulation blood within the ventricles.Subsequent hemolysis leads to release extracellular hemoglobin (Hb) into cerebrospinal fl uid (CSF).Hb its metabolites initiate cytotoxic, oxidative, proinfl ammatory, apoptotic pathways resulting tissue damage.Scavenging Hb, using haptoglobin (Hp), may therefore constitute potential...
Amaç: Arkuat foramen (AF) atlasın posterior arkındaki vertebral arter (VA) oluğunda (sulkus arteriae vertebralis) bulunan, prevalansı bölgesel ve etnik faktörler nedeni ile değişebilen osseöz bir varyasyondur.AF'nin içindeki yapılara bası oluşturarak vertebrobaziler yetmezlik bulgularına neden olduğu düşünülse de bu kliniği açıklayacak yeterli sayıda kadavra çalışması yoktur.Yöntemler: AF varyasyonun insidansını içinden geçen VA olan ilişkisini değerlendirmek için renkli silikon enjekte...
The superficial temporal artery (STA) to the middle cerebral (MCA) bypass is most common type for revascularization treat ischemia. If ipsilateral STA not available anastomosis, various options conduits can be exercised. When entire external carotid and its branches are available, contralateral may used as a donor through an interposition graft. This technique known "bonnet bypass." In this video, we demonstrate utilization of bonnet in 48-yr-old man with protein S deficiency, right...
Surgical treatment of the gliomas located in or adjacent to eloquent areas poses significant challenge neurosurgeons. The main goal surgery is achieve maximal safe resection while preserving neurological function. This might be possible with utilizing pre- and intraoperative adjuncts such as functional magnetic resonance imaging (MRI), image guidance, mapping function interest, MRI, neurophysiological monitoring. In this video, we demonstrate utilization nonawake motor-evoked potential (MEP)...
Abstract Background: Brachial plexus injury (BPI) occurs when the brachial is compressed, stretched, or avulsed. Although rodents are commonly used to study BPI, these models poorly mimic human BPI due discrepancy in size. The objective of this was compare between and Wisconsin Miniature Swine TM (WMS ), which approximately weight an average (68–91 kg), determine if swine would be a suitable model for studying mechanisms treatments. Methods: To analyze gross anatomy, WMS plexi were dissected...
Compressive syndromes of the cervical arteries caused by musculoskeletal structures include bow hunter's syndrome, beauty parlour stroke carotid compression hyoid bone, digastric muscle and Eagle syndrome. They are a rare but increasingly recognised group syndromes, so high level suspicion is needed diagnosis not missed. The typically based on combination clinical history advanced imaging investigations. Compression may be static (only provoked compression) or dynamic (exaggerated movement),...