A5028878214- Knee injuries and reconstruction techniques
- Sports injuries and prevention
- Total Knee Arthroplasty Outcomes
- Lower Extremity Biomechanics and Pathologies
- Mast cells and histamine
- Shoulder Injury and Treatment
- Tendon Structure and Treatment
- Muscle activation and electromyography studies
- Orthopaedic implants and arthroplasty
- Foot and Ankle Surgery
- Neuropeptides and Animal Physiology
- Asthma and respiratory diseases
- Bone Tissue Engineering Materials
- Urticaria and Related Conditions
- Adhesion, Friction, and Surface Interactions
- Immune Cell Function and Interaction
- Orthopedic Surgery and Rehabilitation
- IL-33, ST2, and ILC Pathways
- Bone fractures and treatments
- Advanced Sensor and Energy Harvesting Materials
- Chemokine receptors and signaling
- Shoulder and Clavicle Injuries
- Electrospun Nanofibers in Biomedical Applications
- Sports Performance and Training
- Cardiovascular Effects of Exercise
Agostino Gemelli University Polyclinic
2014-2019
Università Cattolica del Sacro Cuore
2014-2017
University of Perugia
2007-2016
Catholic University of America
2015
Faculty (United Kingdom)
2014
University of Chieti-Pescara
2009
Azienda Ospedaliera di Perugia
2005
In this study, we investigated whether multipotent (human-bone-marrow-derived mesenchymal stem cells [hBM-MSCs]) and pluripotent (murine-induced [iPSCs] murine embryonic [ESCs]) respond to nanocomposite fibrous mats of poly(L-lactic acid) (PLLA) loaded with 1 or 8 wt % calcium-deficient nanohydroxyapatite (d-HAp). Remarkably, the dispersion different amounts d-HAp PLLA produced a set materials (PLLA/d-HAp) similar architectures tunable mechanical properties. After 3 weeks culture in absence...
This study investigated how the design of surface topography may stimulate stem cell differentiation towards a neural lineage. To this end, hydrogenated amorphous carbon (a-C:H) groove topographies with width/spacing ridges ranging from 80/40μm, 40/30μm and 30/20μm depth 24 nm were used as single mechanotransducer stimulus to generate cells human bone marrow mesenchymal (hBM-MSCs) in vitro. As comparative experiments, soluble brain-derived neurotrophic factor (BDNF) was additional...
The interaction between stem cells and biomaterials with nanoscale topography represents a main route in the roadmap for tissue engineering–based strategies. In this study, we explored interface human bone marrow–derived mesenchymal (hBM-MSCs) hydrogenated amorphous carbon (a-C:H) film designed uniform, groove, or grid nanopatterns. either case, hBM-MSCs preserved growth rate multi-differentiation properties, suggesting that films were biocompatible suitable cell culture. responded to...
Osteoarthritis (OA) of the knee is most common form non-traumatic joint disease. Previous studies have shown involvement β-NGF and its receptors TrKA p75NTR in OA-related pain, but their role pathogenesis still unclear. The aim our study was to investigate amount expression levels on cells isolated from synovial fluid blood OA patients who had undergone total arthroplasty, order check any possible correlation with disease staging. Our results show a progressive stage-related increase both...
This commentary describes a program developed to help reduce the incidence of anterior cruciate ligament injuries in soccer players. The basic principles underlying injury prevention protocol are described with respect proprioceptive control mechanisms at knee joint. is followed by detailed description program. J Orthop Sports Phys Ther 2001;31:655–660.