A5100331754- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac Fibrosis and Remodeling
- Cardiac pacing and defibrillation studies
- Software System Performance and Reliability
- ECG Monitoring and Analysis
- Connective Tissue Growth Factor Research
- Network Security and Intrusion Detection
- Advanced biosensing and bioanalysis techniques
- Ginseng Biological Effects and Applications
- Phonocardiography and Auscultation Techniques
- Antiplatelet Therapy and Cardiovascular Diseases
- Human Mobility and Location-Based Analysis
- Structural Health Monitoring Techniques
- Cloud Computing and Resource Management
- Geographic Information Systems Studies
- Heart Rate Variability and Autonomic Control
- Software-Defined Networks and 5G
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Blood Coagulation and Thrombosis Mechanisms
- Cardiac electrophysiology and arrhythmias
- Traditional Chinese Medicine Analysis
- Protease and Inhibitor Mechanisms
- Probabilistic and Robust Engineering Design
- Chromatography in Natural Products
Nanjing University of Chinese Medicine
2023
Guangxi Academy of Special Crops
2018
Affiliated Hospital of Guizhou Medical University
2018
Guiyang Medical University
2018
Shanghai Chest Hospital
2013-2017
Beijing Electronic Science and Technology Institute
2017
State Key Laboratory of Genetic Engineering
2016
Fudan University
2016
Shanghai Jiao Tong University
2011-2013
Atrial fibrillation (AF) is the most frequent cardiac arrhythmia and a major cause of morbidity mortality. Previous studies have established genetic defects as risk factor for AF in minority patients. However, substantial heterogeneity molecular determinants majority cases remain unclear. In this study, entire coding sequence splice junctions GATA4, which encodes zinc-finger transcription essential cardiogenesis, were sequenced 160 unrelated patients with lone AF. A total 200 ethnically...
OBJECTIVE:The aim of this study was to evaluate the prevalence and spectrum Nkx2.5 mutations associated with idiopathic atrial fibrillation (AF).METHODS: A cohort 136 unrelated patients 200 unrelated, ethnically matched healthy controls were enrolled.The coding exons splice junctions gene sequenced in patients, available relatives mutation carriers subsequently genotyped for identified mutations.The functional characteristics mutated analyzed using a dual-luciferase reporter assay...
<b><i>Objective:</i></b> Atrial remodeling is involved in atrial fibrillation (AF), and fibrosis an important marker of remodeling. On the basis our previous animal studies mitogen-activated protein kinases (MAPKs)/transforming growth factor β1 (TGF-β1)/tumor necrosis pathway fibrosis, we undertook investigation this signaling patients with chronic AF (CAF) rheumatic mitral valve disease. <b><i>Methods:</i></b> Fifty-six disease were divided...
Objectives To explore the relationship between MAPKs/TGF-β1/TRAF6 signaling pathway and atrial fibrosis in patients with rheumatic heart disease (RHD) its role fibrillation (AF) after cardiac surgery on basis of our previous animal study fibrosis. Methods A total 57 RHD without a history AF consented to left biopsy. Histopathology quantified percentage fibrosis, real-time PCR western blot assessed mRNA protein expression TGF-β1, TRAF6, connective tissue growth factor (CTGF), respectively....
To observe the clinical features of atrial fibrillation (AF) patients, and to explore correlation between routine detection index new-onset AF find out risk factors for new in critically ill patients.A prospective observational study was conducted. The patients with admitted intensive care unit (ICU) Affiliated Hospital Guizhou Medical University from March 2016 June 2017 were enrolled. divided into group past-existed according their past history (including persistent AF, paroxysmal or...
Although Qixue Shuangbu Prescription (QSP) is a classic Chinese medicine prescription for treating chronic heart failure. Low bioavailability due to the insolubility and poor biofilm permeability of main bioactive ingredients QSP still key factor limiting its efficacy. In this study, novel self‐microemulsifying drug delivery system was proposed effectively improve QSP. The qualified ultra‐high‐performance liquid chromatography‐tandem mass spectrometry methodology established investigate...
Atrial fibrillation (AF) is one of the most great challenges cardiology in twenty-first century. The prevalence AF increases with age, ranging from 1% youth to approximately 10% among those over age 80 years.1 Three million people United States are affected by AF, and number estimated increase 5.6 2050 owing both aging population alarming rise individuals risk factors for AF.1 Similar trends also found China.2 intense independent factor stroke heart failure, 20% strokes related while nearly...
An efficient method, namely fixed interface mode synthesis-interval factor method (FIMS-IFM), is proposed to calculate the natural frequency of structure considering elastic joint with interval uncertainty. In this uncertain treated as spatial beam element material parameters. Additionally, both and Monte-Carlo simulation are used a specially designed joint. A meaningful conclusion can be acquired via comparing calculation results two methods that, FIMS-IFM correct high-efficiency.
Objective The purpose of this study is to compare the short-term clinical effect and electrical parameters peri-left bundle pacing (peri-LBBP) right ventricular inflow tract septal (RVIP) . Methods Sixty patients with indications for permanent cardiac resynchronization therapy were divided into peri-LBBP RVIP groups in Beijing Anzhen Hospital from April 2017 September 2018. The Medtronic lead 3830 was used as lead, implanted left sites potentials or fascicular group closed distal...
Objective To compare the short-term clinical effect and electrical parameters of His-purkinje bundle pacing (HPBP) right ventricular inflow tract septal (RVIP) in elderly. Methods Between April 2017 September 2019, sixty patients with indications for permanent cardiac resynchronization therapy Beijing Anzhen Hospital were divided into HPBP RVIP groups, analyzed. A lead was implanted left sites potentials or His group. The placed close to distal His-bundle regions without from conduction...
Deep learning models are modern tools for spatio-temporal graph (STG) forecasting. Though successful, we argue that data scarcity is a key factor limiting their recent improvements. Meanwhile, contrastive has been an effective method providing self-supervision signals and addressing in various domains. In view of this, one may ask: can leverage the additional from to alleviate scarcity, so as benefit STG forecasting? To answer this question, present first systematic exploration on...