A5036958205- Liver Disease Diagnosis and Treatment
- Influenza Virus Research Studies
- Vaccine Coverage and Hesitancy
- Hepatitis B Virus Studies
- Inflammatory Bowel Disease
- Heme Oxygenase-1 and Carbon Monoxide
- Diverticular Disease and Complications
- Respiratory viral infections research
- Endoplasmic Reticulum Stress and Disease
- Cardiac pacing and defibrillation studies
- Liver Disease and Transplantation
- Cardiac Arrhythmias and Treatments
- Anorectal Disease Treatments and Outcomes
- Hepatocellular Carcinoma Treatment and Prognosis
- Child and Adolescent Health
- Viral gastroenteritis research and epidemiology
- Liver physiology and pathology
- Ferroptosis and cancer prognosis
- Tissue Engineering and Regenerative Medicine
- Microscopic Colitis
- Circular RNAs in diseases
- Cancer, Lipids, and Metabolism
- Acute Myocardial Infarction Research
- Acute Kidney Injury Research
- Alcohol Consumption and Health Effects
Third Hospital of Hebei Medical University
2014-2024
Hebei Medical University
2014-2024
Hospital of Hebei Province
2022
Second Military Medical University
2020-2021
University of Michigan
2011-2019
Beijing Anzhen Hospital
2019
Capital Medical University
2019
Michigan United
2019
Michigan Department of Education
2013
National Center for Immunization and Respiratory Diseases
2013
ABSTRACT Background: Although perianal complications of Crohn disease (CD) are commonly encountered in clinical practice, the epidemiology CD among populations children is poorly understood. We sought to characterize prevalence a large and diverse population pediatric patients with CD. Methods: conducted retrospective analyses from prospective observational cohort, ImproveCareNow Network (May 2006–October 2014), multicenter inflammatory bowel quality improvement collaborative. Clinicians...
Purpose: The incidence of non-B and non-C hepatocellular carcinoma (NBNC-HCC) is increasing globally. Metabolically associated fatty liver disease (MAFLD) has been a contributing factor to this rising trend in NBNC-HCC incidence. monocyte-to-high-density lipoprotein-cholesterol ratio (MHR) new prognostic marker that connects systemic inflammation with disorders lipid metabolism. Therefore, MHR may be potential predictor patients MAFLD-related HCC (MAFLD-HCC). This study aims investigate the...
Abstract Aim Nonalcoholic steatohepatitis (NASH) is a severe form of nonalcoholic fatty liver disease (NAFLD) and lacks effective treatment options. Heme oxygenase‐1 (HO‐1) critical defense against oxidative stress inflammation in the injury. This study aims to investigate protective role underlying mechanisms HO‐1 NASH pathogenesis. Methods The hepatocyte‐specific knockout (HO‐1 HEPKO ) mice on C57BL/6J background fl/fl /Alb‐Cre) were generated fed high‐fat/western‐style diet (HFD) or...
To effectively prevent recurrence, improve the prognosis and increase survival rate of primary liver cancer (PLC) patients with radical cure, Chinese Society Hepatology, Medical Association, invited clinical experts methodologists to develop Consensus on Tertiary Prevention Primary Liver Cancer, which was based scientific advances risk factors, histopathology, imaging finding, manifestation, prevention recurrence PLC. The purpose is provide a current basis for prevention, surveillance, early...
To assess the accuracy of using administrative data from state-managed programs to identify children with asthma in a statewide immunization information system. We wished understand degree which alternative case definitions applied influence cases identified an system.Children aged 2 18 years were sequentially classified into 3-case definition groups on basis Michigan Department Community Health (2005-2006): (1) Children's Special Care Services (CSHCS) Program qualifying diagnosis (CSHCS...
As the major subtype of liver cancer, hepatocellular carcinoma (HCC) suffers from high mortality and is prone to recurrence. Long non-coding RNAs (lncRNAs) are well characterized be pivotal players contributing HCC pathogenesis progression. Therefore, this study intended probe biological functions LINC00886 in hepatocarcinogenesis.Quantitative real-time polymerase chain reaction (qRT-PCR) was applied analysis LINC00886, microRNA-409-3p (miR-409-3p), microRNA-214-5p (miR-214-5p), RAB10 E2F2...
The aim of this study was to find novel biomarkers and develop a non-invasive, effective diagnostic model for hepatitis B Virus-related chronic liver fibrosis/cirrhosis.
We evaluated the use of a statewide immunization information system (IIS) to target influenza vaccine reminders high-risk children during pandemic.We used Michigan's IIS identify (i.e., those with ≥ 1 chronic condition) aged 6 months 18 years no record pH1N1 vaccination among currently or previously enrolled in Medicaid (n = 202,133). Reminders were mailed on December 7, 2009. retrospectively assessed children's eligibility for evaluation and compared rates across 3 groups basis their...
Objective. Immunization information systems (IISs) are valuable surveillance tools; however, population relocation may introduce bias when determining immunization coverage We explored alternative methods for estimating the vaccine-eligible calculating adolescent levels using a statewide IIS. Methods. performed retrospective analysis of Michigan State Care Improvement Registry (MCIR) all adolescents aged 11–18 years registered in MCIR as October 2010. four denominators: (1) including with...
Objective: To explore whether Integrated Early Childhood Development (IECD) program has effectively improved the nurturing care for children aged 0-35 months in rural China. Methods: IECD been implemented by government of China with support from United Nations Children's Fund (UNICEF) four poverty-stricken counties since 2014. The interventions targeting five key components (i.e. child and caregiver health, nutrition, early learning support, protection social security) were delivered through...
The aim of this study was to identify potential plasma biomarkers for hepatitis B virus (HBV)-related liver diseases. High-throughput transcriptome sequencing analysis performed on five patients with chronic (CHB), HBV-associated fibrosis/liver cirrhosis (LF/LC), and four healthy participants. By short time-series expression miner functional analysis, aquaporin 1 (AQP1), dystroglycan (DAG1), hemoglobin subunit beta (HBB) were identified as biomarkers. Immunohistochemical revealed that the...
Purpose: The aim of this study was to identify and validate novel biomarkers for distinguishing among hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC), liver fibrosis/liver cirrhosis (LF/LC) chronic (CHB). Patients Methods: Transcriptomic sequencing conducted on the tissues 5 patients with HCC, LF/LC, CHB, 4 healthy controls. expression levels selected mRNAs proteins were assessed by quantitative real-time polymerase chain reaction (qRT-PCR) immunohistochemical (IHC) staining,...
Background: Computed tomography-derived fractional flow reserve (CT-FFR) has emerged as a promising non-invasive substitute for (FFR) measurement. Normally, CT-FFR providing functional significance of coronary artery disease (CAD) by using simplified total resistance index (TCRI) model. Yet the error or discrepancy caused this model remains unclear. Methods: A 20 consecutive patients with suspected CAD who underwent CTA and invasive FFR measurement were retrospectively analyzed....
The Yiqi Huoxue (YQHX) recipe has been shown to attenuate liver fibrosis, but precise mechanisms have not yet elucidated. Recently, Yes-associated protein (YAP)/transcriptional coactivator with PDZ-binding motif (TAZ) signaling implicated in fibrogenesis. This study investigated whether the YAP/TAZ is involved therapeutic effect of YQHX on hepatic fibrosis.
Although perianal fistulas occur commonly in pediatric Crohn's disease (CD), evaluations of health services have been limited since no validated claims-based methods exist for identifying cases.To develop and validate accurate case definitions among patients with CD from administrative claims.Retrospective cohort study which we developed tested candidate fistula. Patients (age 5-21 years between 2005-2012) enrolled Michigan Medicaid healthcare at University were identified via claims....
Objective To evaluate the effect of methylene blue pertreatment on acute kidney injury induced by sepsis in rats.Methods Ninety male Sprague-Dawley rats,aged 1.5-2.5 months,weighing 200-250 g,were randomly assigned into 3 groups (n =30 each) using a random number table:sham operation group (S group),cecal ligation and puncture (CLP) (MB group).The rats were anesthetized with 10％ chloral hydrate 350 mg/kg.Normal saline 0.8 ml was injected via caudal vein CLP groups,while 15 mg/kg (in normal...