- Sepsis Diagnosis and Treatment
- Hemodynamic Monitoring and Therapy
- Heart Failure Treatment and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Renal function and acid-base balance
- Hydrogen's biological and therapeutic effects
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- S100 Proteins and Annexins
- Ferroptosis and cancer prognosis
- Cancer, Lipids, and Metabolism
- Venous Thromboembolism Diagnosis and Management
- Lipoproteins and Cardiovascular Health
- Alcoholism and Thiamine Deficiency
- Nosocomial Infections in ICU
- GDF15 and Related Biomarkers
- Healthcare cost, quality, practices
- MicroRNA in disease regulation
- Intensive Care Unit Cognitive Disorders
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Circular RNAs in diseases
- Pneumonia and Respiratory Infections
- Biomarkers in Disease Mechanisms
- Respiratory Support and Mechanisms
- Atrial Fibrillation Management and Outcomes
First Affiliated Hospital of Jinan University
2021-2023
Creative Commons
2023
Nanjing Medical University
2022
Abstract Background Previous studies have indicated that the ratio of lactate/albumin (L/A) has predictive value for prognosis critically ill patients with heart failure. Some also a low serum bicarbonate concentration is inversely related to mortality risk cardiogenic shock. However, and L/A predicting acute myocardial infarction (AMI) still unclear. We therefore conducted retrospective study research this problem. Methods The subjects were AMI, data source was Medical Information Mart...
Background: Ventilator-associated pneumonia (VAP) is a common infection complication in intensive care units (ICU). It not only prolongs mechanical ventilation and ICU hospital stays, but also increases medical costs the mortality risk of patients. Although many studies have found that thiamine supplementation critically ill patients may improve prognoses, there still no research or evidence beneficial for with VAP. The purpose this study was to determine association between prognoses...
Background: In intensive care units (ICUs), the morbidity and mortality of ventilator-associated pneumonia (VAP) are relatively high, this condition also increases medical expenses for mechanically ventilated patients, which will seriously affect prognoses critically ill patients. The purpose study was to determine impact bronchoscopy on prognosis patients with VAP undergoing invasive mechanical ventilation (IMV). Methods: This a retrospective based from Medical Information Mart Intensive...
Phenylephrine (PE) and norepinephrine (NE) may be used to maintain adequate blood pressure tissue perfusion in patients with septic shock, but the effect of NE combined PE (NE-PE) on mortality remains unclear. We hypothesized that NE-PE would not inferior alone for all-cause hospital shock.This single-center, retrospective cohort study included adult shock. According infusion type, were divided into or group. Multivariate logistic regression, propensity score matching doubly robust...
Type 2 diabetes leads to an increase in the prevalence of lipid abnormalities, which increases risk cardiovascular disease. Therefore, current guidelines generally recommend use moderate or high-intensity statins patients with type diabetes. There are still few studies on overall benefit balance for acute myocardial infarction (AMI) Compared other types lipid-lowering drugs, advantage prognosis AMI has not yet been determined. We investigated effects and non-statins intensive care unit (ICU)...
ABSTRACT Sepsis is considered a life-threatening organ dysfunction resulting from dysregulation of the body's response to infection, syndrome physiological, pathological, and biochemical abnormalities caused by infection. The prevention treatment sepsis-related acute lung injury has become hot spot in sepsis research recent years. Neutrophil elastase (NE) multifunctional serine protease released neutrophils cells, which can participate regulation inflammatory body directly affect occurrence...
ABSTRACT Background: Acute kidney injury (AKI) is a rapid decline in renal function characterized by decrease glomerular filtration rate short period. Ferroptosis affects the development of various diseases. Therefore, searching for genes related to ferroptosis crucial understanding occurrence and AKI. Methods: We obtained data from 18 samples (8 with acute 10 non-pathological tissue) GSE53769 48 (39 9 GSE139061. differentially expressed (DEGs) AKI/Control both two datasets intersected them...
Abstract BACKGROUND Phenylephrine (PE) and norepinephrine (NE) may be used to maintain adequate blood pressure tissue perfusion in patients with septic shock, but the effect of NE combined PE (NE-PE) on mortality remains unclear. We hypothesized that NE-PE would not inferior alone for all-cause hospital shock. METHODS This single-center, retrospective cohort study included adult According infusion type, were divided into or group. Multivariate logistic regression, propensity score matching...
Abstract Sepsis is one of the most common severe diseases in clinic. With progression disease, it very likely to occur acute lung injury (ALI)/acute respiratory distress syndrome (ARDS). Despite years research, mortality rate from sepsis-associated remains high. MicroRNAs (miRNAs) are a class non-coding small RNAs with function regulating gene expression. In recent years, miRNAs have become research hotspot field biomedicine. Therefore, this review summarizes large body evidence implicating...