A5071251829- Viral Infections and Vectors
- Fire effects on ecosystems
- Vector-borne infectious diseases
- Vector-Borne Animal Diseases
- Viral Infections and Outbreaks Research
- Malaria Research and Control
- Parasitic Infections and Diagnostics
- Healthcare and Venom Research
- Mosquito-borne diseases and control
- Bartonella species infections research
- Microbial infections and disease research
- Rheumatoid Arthritis Research and Therapies
- Hepatitis B Virus Studies
- Child Nutrition and Water Access
- Viral gastroenteritis research and epidemiology
- Virus-based gene therapy research
- Multiple Sclerosis Research Studies
- Clostridium difficile and Clostridium perfringens research
- Herpesvirus Infections and Treatments
- Autism Spectrum Disorder Research
- CRISPR and Genetic Engineering
- Retinal Imaging and Analysis
- Aquaculture disease management and microbiota
- Retinopathy of Prematurity Studies
- Virology and Viral Diseases
Affiliated Hospital of Jining Medical University
2024-2025
Kyungpook National University
2024
Korea University
2001-2024
Agency for Defense Development
2018
United States Army Medical Research Institute of Infectious Diseases
2018
National Eye Institute
2011
Jeonbuk National University
2005
National Institute of Neurological Disorders and Stroke
1996
National Institutes of Health
1996
University of New Mexico
1995
We investigated the prevalence of Bartonella infections in ticks, mites and small mammals (rodents, insectivores weasels) collected during 2001 through 2004, from various military installations training sites Korea, using PCR sequence analysis 16S rRNA, 23S rRNA groEL heat shock protein genes. The spp. was 5.2% (n = 1,305 sample pools) 19.1% 21) mesostigmatid 13.7% 424 individuals) mammals. within family Ixodidae was, 4.4% 1,173) Haemaphysalis longicornis (scrub tick), 2.7% 74) H. flava,...
The complete M segment sequences of hantaviruses amplified from tissues a patient with hantavirus pulmonary syndrome in the northeastern United States and white-footed mice, Peromyscus leucopus, New York were 99% identical differed those Four Corners virus by 23%. serum this failed to recognize conserved, immunodominant epitope G1 glycoprotein. Collectively, these findings indicate that P. leucopus harbors genetically antigenically distinct causes syndrome.
Seoul virus (SEOV) poses a worldwide public health threat.This virus, which is harbored by Rattus norvegicus and R. rattus rats, the causative agent of hemorrhagic fever with renal syndrome (HFRS) in humans, has been reported Asia, Europe, Americas, Africa.Defining SEOV genome sequences plays critical role development preventive therapeutic strategies against unique hantavirus.We applied multiplex PCR-based next-generation sequencing to obtain from clinical reservoir host...
Retinal dystrophy (RD) is a broad group of hereditary disorders with heterogeneous genotypes and phenotypes. Current available genetic testing for these diseases complicated, time consuming, expensive. This study was conducted to develop apply microarray-based, high-throughput resequencing system detect sequence alterations in genes related inherited RD.A customized 300-kb chip, Retina-Array, developed 267,550 bases both sense antisense 1470 exons spanning 93 involved RD. Retina-Array...
The merozoite surface protein-1 (MSP-1) of Plasmodium vivax exhibits great antigenic diversity among different isolates this parasite. This antigen is a useful genetic marker for studying the polymorphism natural P. parasite populations. One or more these populations has been responsible resurgent malaria now occurring in Korea. paper reports analysis highly polymorphic region between interspecies conserved blocks 5 and 6 MSP-1 gene, using polymerase chain reaction to amplify DNA fragment...
The amino-acid sequences corresponding to the circumsporozoite protein (CSP) of Plasmodium vivax fall into two main types, VK210 and VK247, each which has a characteristic tandem repeat. When repetitive domains CSP gene from six isolates P. South Korea were sequenced they found show total 20 repeats, repeat patterns that are regular distinct those other isolates. Korean parasites be most similar three China (CH-3, CH-4, CH-5) and, particularly, one North Korea. A sequence (AGGNAANKKAEDAGGNA)...
To determine the prevalence of Bartonella species and identify which naturally infects striped field mouse (Apodemus agrarius) in Republic Korea (ROK), spleens from 200 mice were assayed by nested polymerase chain reaction (nPCR) targeting RNA subunit beta (rpoB) gene 16S-23S internal transcribed spacer (ITS) region for members genus Bartonella. Utilizing PCR techniques, spp. ranged 31.5% (63/200) to 62.0% (124/200) rpoB ITS fragments, respectively. The most prevalent species, grahamii, was...
The prevalence of tick-borne pathogens (TBP), Orientia tsutsugamushi, Rickettsia and Borrelia spp. in wild small animals, namely rodents, is now widely investigated. This study to present the distribution O. animals ticks collected from Gyeonggi Gangwon provinces, Republic Korea (ROK) 2014. A total 131 rodents shrews, 2,954 were provinces May November (KR1-9) (K1-17) grouped accordance with capture dates locations. Among a 393 tissues blood samples extracted six selected animal series...
The amino-acid sequences corresponding to the circumsporozoite protein (CSP) of Plasmodium vivax fall into two main types, VK210 and VK247, each which has a characteristic tandem repeat. When repetitive domains CSP gene from six isolates P. South Korea were sequenced they found show total 20 repeats, repeat patterns that are regular distinct those other isolates. Korean parasites be most similar three China (CH-3, CH-4, CH-5) and, particularly, one North Korea. A sequence (AGGNAANKKAEDAGGNA)...
In February 2019, the order Bunyavirales, previously family Bunyaviridae, was amended by new of 10 families including Hantaviridae family, and now accepted International Committee on Taxonomy Viruses (ICTV). is a prototype virus species Hantaan orthohantavirus. The divided into four subfamilies Mammantavirinae, Repantavirinae, Actantavirinae Agantavirinae. subfamily Mammantavirinae genera Orthohantavirus, Loanvirus, Mobatvirus Thottimvirus. Hantavirus have been found in Korea three...